Results: Ligand

Ligand ID: DAH

Drugbank ID:
Levodopa
(DB01235)

Indication:
Levodopa is a dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism.

LIST OF BINDING INTERFACES for query 'DAH'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1IVV_A_DAHA382	1ivv	DAH	Levodopa (DB01235)	Arthrobacter globiformis	AMINE OXIDASE	Cu_amine_oxid	17	TYR A 284 THR A 377 THR A 378 ILE A 379 GLY A 380 ASN A 381 ASP A 383 TYR A 384 THR A 403 GLY A 404 VAL A 405 VAL A 406 PHE A 407 HIS A 431 HIS A 433 HIS A 592 MET A 602	DAH A 382
1RNR_A_DAHA208	1rnr	DAH	Levodopa (DB01235)	Escherichia coli	RIBONUCLEOTIDE REDUCTASE R1 PROTEIN	Ribonuc_red_sm	16	LEU A 83 ASP A 84 GLN A 87 GLU A 115 HIS A 118 TYR A 122 LEU A 203 GLU A 204 ILE A 206 ARG A 207 TYR A 209 VAL A 210 SER A 211 PHE A 212 ILE A 234 GLU A 238	DAH A 208
2VH3_A_DAHA2	2vh3	DAH	Levodopa (DB01235)	Polypedates leucomystax	RANASMURFIN	NA	12	ALA A 1 ALA A 3 CYS A 4 SER A 5 PHE A 6 GLY A 27 PHE A 28 LYS A 31 ASP A 55 SER A 58 ALA A 59 CYS A 62	DAH A 2
3TEG_A_DAHA416	3teg	DAH	Levodopa (DB01235)	Homo sapiens	PHENYLALANYL-TRNA SYNTHETASE, MITOCHONDRIAL	FDX-ACB tRNA-synt_2d	15	HIS A 119 SER A 121 GLN A 124 ARG A 143 GLN A 157 GLU A 159 PHE A 232 PHE A 234 THR A 235 GLY A 254 CYS A 255 GLY A 256 ALA A 275 PHE A 276 GLY A 277	DAH A 416
3TEH_A_DAHA351	3teh	DAH	Levodopa (DB01235)	Thermus thermophilus	PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN	Phe_tRNA-synt_N tRNA-synt_2d	18	TRP A 149 THR A 177 HIS A 178 SER A 180 GLN A 183 ARG A 204 GLN A 218 GLU A 220 GLY A 221 PHE A 258 PHE A 260 VAL A 261 GLY A 282 ALA A 283 GLY A 284 ALA A 314 PHE A 315 GLY A 316	DAH A 351
3TEH_B_DAHB786	3teh	DAH	Levodopa (DB01235)	Thermus thermophilus	PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN	B3_4 B5 FDX-ACB tRNA_bind tRNA_synthFbeta	13	PRO B 259 MET B 260 HIS B 261 LEU B 286 ALA B 314 GLY B 315 VAL B 316 MET B 317 GLY B 318 GLU B 334 PHE B 338 ALA B 356 PHE B 360	DAH B 786
4EIS_A_DAHA24	4eis	DAH	Levodopa (DB01235)	Neurospora crassa	POLYSACCHARIDE MONOOXYGENASE-3	AA9	11	PRO A 19 TYR A 20 TYR B 20 GLN A 21 ASP A 22 PRO A 23 MET A 25 GLY A 26 ASN B 39 PRO B 79 HIS B 82	DAH A 24
4P6S_A_DAHA304	4p6s	DAH	Levodopa (DB01235)	Bacillus megaterium	TYROSINASE	Tyrosinase	5	ASN A 10 LEU A 12 HIS A 13 GLU A 93 THR A 96	DAH A 304
4P6S_A_DAHA305	4p6s	DAH	Levodopa (DB01235)	Bacillus megaterium	TYROSINASE	Tyrosinase	14	HIS A 42 HIS A 60 PHE A 197 PRO A 201 HIS A 204 ASN A 205 HIS A 208 ARG A 209 MET A 215 GLY A 216 VAL A 217 VAL A 218 ALA A 221 PHE A 227	DAH A 305
5XDH_A_DAHA60	5xdh	DAH	Levodopa (DB01235)	Candidatus jettenia caeni	PUTATIVE CYTOCHROME C	NA	11	HIS A 15 GLN C 27 SER A 50 MET A 51 THR A 55 ASN A 57 PRO A 58 ASN A 59 VAL A 61 LYS A 62 LEU A 63	DAH A 60
5Z0F_B_DAHB98	5z0f	DAH	Levodopa (DB01235)	Streptomyces castaneoglobisporus	MELC; TYROSINASE	MelC1 Tyrosinase	16	HIS A 38 ILE A 42 HIS A 54 SER B 96 HIS B 97 ASP B 99 PRO B 100 TRP A 184 HIS A 190 ASN A 191 HIS A 194 VAL A 195 MET A 201 ALA A 202 THR A 203 SER A 206	DAH B 98
6EBP_A_DAHA123	6ebp	DAH	Levodopa (DB01235)	Aerococcus urinae (strain acs-120-v-col10a)	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE, BETA SUBUNIT	Ribonuc_red_sm	16	PHE A 78 LEU A 81 THR A 82 ASP A 85 HIS A 119 ALA A 120 ARG A 121 SER A 122 GLY A 124 THR A 125 ILE A 126 PHE A 127 LEU A 180 PHE A 184 ILE A 203 ILE A 206	DAH A 123
6GP2_A_DAHA126	6gp2	DAH	Levodopa (DB01235)	Mesoplasma florum (strain atcc 33453 / nbrc 100688 / nctc 11704 / l1)	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE BETA CHAIN	Ribonuc_red_sm	16	PHE A 81 LEU A 84 THR A 85 ASP A 88 HIS A 122 ALA A 123 ARG A 124 SER A 125 GLY A 127 SER A 128 ILE A 129 PHE A 130 PHE A 187 ILE A 206 ILE A 209 LYS A 213	DAH A 126
6JU5_A_DAHA513	6ju5	DAH	Levodopa (DB01235)	Aspergillus oryzae	TYROSINASE	Tyosinase_C Tyrosinase	16	HIS A 67 HIS A 94 HIS A 328 ASN A 329 HIS A 332 MET A 356 SER A 357 SER A 358 VAL A 359 ALA A 362 PHE A 368 ARG A 476 PHE A 511 ASN A 512 TYR A 513 SER A 514	DAH A 513
6ON3_A_DAHA204	6on3	DAH	Levodopa (DB01235)	Streptomyces sclerotialus	L-DOPA EXTRADIOL DIOXYGENASE	Glyoxalase	14	HIS A 19 TRP A 44 LEU A 46 LYS A 48 PHE A 49 SER A 50 THR A 53 ARG A 56 LEU A 63 HIS A 74 HIS B 95 ASP B 136 TYR B 144 GLU B 154	DAH A 204
6PAH_A_DAHA600	6pah	DAH	Levodopa (DB01235)	Homo sapiens	PHENYLALANINE 4-MONOOXYGENASE	NA	8	LEU A 248 SER A 251 PHE A 254 PRO A 281 HIS A 285 HIS A 290 TYR A 325 GLU A 330	DAH A 600
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1IVV_A_DAHA382","1ivv","DAH","Levodopa (DB01235)","Arthrobacter globiformis","AMINE OXIDASE","Cu_amine_oxid",17,"TYR A 284;THR A 377;THR A 378;ILE A 379;GLY A 380;ASN A 381;ASP A 383;TYR A 384;THR A 403;GLY A 404;VAL A 405;VAL A 406;PHE A 407;HIS A 431;HIS A 433;HIS A 592;MET A 602","DAH A 382\r"],["1RNR_A_DAHA208","1rnr","DAH","Levodopa (DB01235)","Escherichia coli","RIBONUCLEOTIDE REDUCTASE R1 PROTEIN","Ribonuc_red_sm",16,"LEU A  83;ASP A  84;GLN A  87;GLU A 115;HIS A 118;TYR A 122;LEU A 203;GLU A 204;ILE A 206;ARG A 207;TYR A 209;VAL A 210;SER A 211;PHE A 212;ILE A 234;GLU A 238","DAH A 208\r"],["2VH3_A_DAHA2","2vh3","DAH","Levodopa (DB01235)","Polypedates leucomystax","RANASMURFIN","NA",12,"ALA A   1;ALA A   3;CYS A   4;SER A   5;PHE A   6;GLY A  27;PHE A  28;LYS A  31;ASP A  55;SER A  58;ALA A  59;CYS A  62","DAH A   2\r"],["3TEG_A_DAHA416","3teg","DAH","Levodopa (DB01235)","Homo sapiens","PHENYLALANYL-TRNA SYNTHETASE, MITOCHONDRIAL","FDX-ACB;tRNA-synt_2d",15,"HIS A 119;SER A 121;GLN A 124;ARG A 143;GLN A 157;GLU A 159;PHE A 232;PHE A 234;THR A 235;GLY A 254;CYS A 255;GLY A 256;ALA A 275;PHE A 276;GLY A 277","DAH A 416\r"],["3TEH_A_DAHA351","3teh","DAH","Levodopa (DB01235)","Thermus thermophilus","PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN","Phe_tRNA-synt_N;tRNA-synt_2d",18,"TRP A 149;THR A 177;HIS A 178;SER A 180;GLN A 183;ARG A 204;GLN A 218;GLU A 220;GLY A 221;PHE A 258;PHE A 260;VAL A 261;GLY A 282;ALA A 283;GLY A 284;ALA A 314;PHE A 315;GLY A 316","DAH A 351\r"],["3TEH_B_DAHB786","3teh","DAH","Levodopa (DB01235)","Thermus thermophilus","PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN","B3_4;B5;FDX-ACB;tRNA_bind;tRNA_synthFbeta",13,"PRO B 259;MET B 260;HIS B 261;LEU B 286;ALA B 314;GLY B 315;VAL B 316;MET B 317;GLY B 318;GLU B 334;PHE B 338;ALA B 356;PHE B 360","DAH B 786\r"],["4EIS_A_DAHA24","4eis","DAH","Levodopa (DB01235)","Neurospora crassa","POLYSACCHARIDE MONOOXYGENASE-3","AA9",11,"PRO A  19;TYR A  20;TYR B  20;GLN A  21;ASP A  22;PRO A  23;MET A  25;GLY A  26;ASN B  39;PRO B  79;HIS B  82","DAH A  24\r"],["4P6S_A_DAHA304","4p6s","DAH","Levodopa (DB01235)","Bacillus megaterium","TYROSINASE","Tyrosinase",5,"ASN A  10;LEU A  12;HIS A  13;GLU A  93;THR A  96","DAH A 304\r"],["4P6S_A_DAHA305","4p6s","DAH","Levodopa (DB01235)","Bacillus megaterium","TYROSINASE","Tyrosinase",14,"HIS A  42;HIS A  60;PHE A 197;PRO A 201;HIS A 204;ASN A 205;HIS A 208;ARG A 209;MET A 215;GLY A 216;VAL A 217;VAL A 218;ALA A 221;PHE A 227","DAH A 305\r"],["5XDH_A_DAHA60","5xdh","DAH","Levodopa (DB01235)","Candidatus jettenia caeni","PUTATIVE CYTOCHROME C","NA",11,"HIS A  15;GLN C  27;SER A  50;MET A  51;THR A  55;ASN A  57;PRO A  58;ASN A  59;VAL A  61;LYS A  62;LEU A  63","DAH A  60\r"],["5Z0F_B_DAHB98","5z0f","DAH","Levodopa (DB01235)","Streptomyces castaneoglobisporus","MELC;TYROSINASE","MelC1;Tyrosinase",16,"HIS A  38;ILE A  42;HIS A  54;SER B  96;HIS B  97;ASP B  99;PRO B 100;TRP A 184;HIS A 190;ASN A 191;HIS A 194;VAL A 195;MET A 201;ALA A 202;THR A 203;SER A 206","DAH B  98\r"],["6EBP_A_DAHA123","6ebp","DAH","Levodopa (DB01235)","Aerococcus urinae (strain acs-120-v-col10a)","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE, BETA SUBUNIT","Ribonuc_red_sm",16,"PHE A  78;LEU A  81;THR A  82;ASP A  85;HIS A 119;ALA A 120;ARG A 121;SER A 122;GLY A 124;THR A 125;ILE A 126;PHE A 127;LEU A 180;PHE A 184;ILE A 203;ILE A 206","DAH A 123\r"],["6GP2_A_DAHA126","6gp2","DAH","Levodopa (DB01235)","Mesoplasma florum (strain atcc 33453 \/ nbrc 100688 \/ nctc 11704 \/ l1)","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE BETA CHAIN","Ribonuc_red_sm",16,"PHE A  81;LEU A  84;THR A  85;ASP A  88;HIS A 122;ALA A 123;ARG A 124;SER A 125;GLY A 127;SER A 128;ILE A 129;PHE A 130;PHE A 187;ILE A 206;ILE A 209;LYS A 213","DAH A 126\r"],["6JU5_A_DAHA513","6ju5","DAH","Levodopa (DB01235)","Aspergillus oryzae","TYROSINASE","Tyosinase_C;Tyrosinase",16,"HIS A  67;HIS A  94;HIS A 328;ASN A 329;HIS A 332;MET A 356;SER A 357;SER A 358;VAL A 359;ALA A 362;PHE A 368;ARG A 476;PHE A 511;ASN A 512;TYR A 513;SER A 514","DAH A 513\r"],["6ON3_A_DAHA204","6on3","DAH","Levodopa (DB01235)","Streptomyces sclerotialus","L-DOPA EXTRADIOL DIOXYGENASE","Glyoxalase",14,"HIS A  19;TRP A  44;LEU A  46;LYS A  48;PHE A  49;SER A  50;THR A  53;ARG A  56;LEU A  63;HIS A  74;HIS B  95;ASP B 136;TYR B 144;GLU B 154","DAH A 204\r"],["6PAH_A_DAHA600","6pah","DAH","Levodopa (DB01235)","Homo sapiens","PHENYLALANINE 4-MONOOXYGENASE","NA",8,"LEU A 248;SER A 251;PHE A 254;PRO A 281;HIS A 285;HIS A 290;TYR A 325;GLU A 330","DAH A 600\r"]]