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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 1dtl | BEP | Bepridil (DB01244) | A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts... | CARDIAC TROPONIN C (Gallus gallus) | EF-hand_7EF-hand_8 | ||
| 1n4f | ASR | Arsanilic acid (DB03006) | An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals. [PubChem] | LYSOZYME C (Gallus gallus) | Lys | ||
| 2fbw | CBE | Carboxin (DB04657) | A systemic agricultural fungicide and seed treatment agent. | SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL;SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL;SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL (Gallus gallus) | Fer2_3Fer4_17Sdh_cyt | ||
| 2jn3 | JN3 | Chenodeoxycholic acid (DB06777) | Chenodeoxycholic acid is a bile acid used for the treatment of primary biliary cirrhosis. | FATTY ACID-BINDING PROTEIN, LIVER (Gallus gallus) | Lipocalin | ||
| 2oiq | STI | Imatinib (DB00619) | Imatinib is a tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Gallus gallus) | PK_Tyr_Ser-Thr | ||
| 2z18 | HDZ | Nitrogen (DB09152) | Nitrogen is a cryogenic agent used to treat various benign and malignant skin lesions. | LYSOZYME C (Gallus gallus) | Lys | ||
| 3g5d | 1N1 | Dasatinib (DB01254) | Dasatinib is a tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy. | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Gallus gallus) | PK_Tyr_Ser-Thr | ||
| 3p73 | 16A | Cetrimonium (DB01718) | Cetrimonium is a compound that can be used as a topical antiseptic. | MHC RFP-Y CLASS I ALPHA CHAIN (Gallus gallus) | C1-setMHC_I | ||
| 3txi | QPT | Carboplatin (DB00958) | Carboplatin is a alkylating agent used to treat advanced ovarian cancer. | LYSOZYME C (Gallus gallus) | Lys | ||
| 4ii8 | 010 | Benzyl alcohol (DB06770) | Benzyl alcohol is an antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older. | LYSOZYME C (Gallus gallus) | Lys | ||
| 4ntx | AMR | Amiloride (DB00594) | Amiloride is a pyrizine compound used to treat hypertension and congestive heart failure. | ACID-SENSING ION CHANNEL 1 (Gallus gallus;micrurus tener tener) | ASC | ||
| 4ntx | AMR | Amiloride (DB00594) | Amiloride is a pyrizine compound used to treat hypertension and congestive heart failure. | ACID-SENSING ION CHANNEL 1;BASIC PHOSPHOLIPASE A2 HOMOLOG TX-BETA (Gallus gallus;micrurus tener tener) | ASCPhospholip_A2_1 | ||
| 4xyy | EDN | Ethylenediamine (DB14189) | Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products. It is also used as an excipient in many pharmacological... | LYSOZYME C (Gallus gallus) | Lys | ||
| 4yeo | CPT | Cisplatin (DB00515) | Cisplatin is a platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors. | LYSOZYME C (Gallus gallus) | Lys | ||
| 5j2t | VLB | Vinblastine (DB00570) | Vinblastine is a vinca alkaloid used to treat breast cancer, testicular cancer, neuroblastoma, Hodgkin's and non-Hodgkins lymphoma, mycosis fungoides, histiocytosis, and Kaposi's sarcoma. | TUBULIN ALPHA-1B CHAIN;TUBULIN BETA-2B CHAIN (Rattus norvegicus;gallus gallus;bos taurus) | TubulinTubulin_C | ||
| 5jh7 | 6K9 | Eribulin (DB08871) | Eribulin is a microtubule inhibitor used to treat metastatic breast cancer and metastatic or unresectable liposarcoma. | TUBULIN ALPHA-1B CHAIN;TUBULIN BETA-2B CHAIN (Rattus norvegicus;gallus gallus;bos taurus) | TubulinTubulin_C | ||
| 5lur | STR | Progesterone (DB00396) | Progesterone is a hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. | AVIDIN (Gallus gallus) | Avidin | ||
| 5lxw | NH3 | Ammonia (DB11118) | Ammonia is a naturally-occurring compound with a chemical formula NH3 and structure of trigonal pyramidal geometry. It is a colorless gas with a pungent smell, and become NH4, or ammonium... | LYSOZYME C (Gallus gallus) | Lys | ||
| 6agn | 9Y6 | Cinnamaldehyde (DB14184) | Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour. It occurs naturally in the bark of cinnamon trees and other species of the genus... | LYSOZYME C (Gallus gallus) | Lys | ||
| 6l8l | 1E8 | Ibrutinib (DB09053) | Ibrutinib is an antineoplastic agent used to treat chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom's Macroglobulinemia. | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC (Gallus gallus) | PK_Tyr_Ser-Thr | ||
| 7daf | GZX | Ixabepilone (DB04845) | Ixabepilone is a microtubule inhibitor administered in combination with capecitabine or alone in the treatment of metastatic or locally advanced breast cancer that has shown inadequate response to taxanes and anthracyclines. | TUBULIN BETA CHAIN (Mus musculus;gallus gallus;sus scrofa) | TubulinTubulin_C | ||
| 7o0k | CHD | Cholic acid (DB02659) | Cholic Acid is a bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function. | FATTY ACID-BINDING PROTEIN, LIVER (Gallus gallus) | Lipocalin | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |