Ligand ID: CPT

Drugbank ID:
Cisplatin
(DB00515)

Indication:
Cisplatin is a platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors.

LIST OF BINDING INTERFACES for query 'CPT'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2AEO_A_CPTA284	2aeo	CPT	Cisplatin (DB00515)	Bos taurus	SUPEROXIDE DISMUTASE [CU-ZN]	Sod_Cu	4	THR A  17 HIS A  19 GLY A  31 SER A  32	CPT A 284		Details
3IWX_A_CPTA69	3iwx	CPT	Cisplatin (DB00515)	Homo sapiens	COPPER TRANSPORT PROTEIN ATOX1	HMA	8	THR B  11 THR A  11 CYS A  12 CYS B  12 GLY A  13 GLY B  14 CYS B  15 CYS A  15	CPT A  69		Details
3RE0_B_CPTB201	3re0	CPT	Cisplatin (DB00515)	Homo sapiens	SUPEROXIDE DISMUTASE [CU-ZN]	Sod_Cu	11	LEU B 106 LEU A 106 SER A 107 SER B 107 GLY B 108 CYS B 111 CYS A 111 ILE B 113 ILE A 113 ILE A 151 ILE B 151	CPT B 201		Details
4N0Z_A_CPTA203	4n0z	CPT	Cisplatin (DB00515)	Plasmodium falciparum	GLUTAREDOXIN	Glutaredoxin	3	ASN A  19 MET A  48 HIS A  49	CPT A 203		Details
4OT4_A_CPTA200	4ot4	CPT	Cisplatin (DB00515)	Bos taurus	RIBONUCLEASE PANCREATIC	RnaseA	5	GLN A  28 MET A  29 SER A  32 ASP B  53 ALA B  56	CPT A 200		Details
4OT4_A_CPTA201	4ot4	CPT	Cisplatin (DB00515)	Bos taurus	RIBONUCLEASE PANCREATIC	RnaseA	6	ASP A  14 SER A  16 TYR A  25 MET A  29 ALA B  56 SER B  59	CPT A 201		Details
4RSZ_A_CPTA202	4rsz	CPT	Cisplatin (DB00515)	Equus caballus	CYTOCHROME C	Cytochrom_C	4	GLU A  61 MET A  65 LYS A  88 GLU A  92	CPT A 202		Details
4S1Y_A_CPTA602	4s1y	CPT	Cisplatin (DB00515)	Homo sapiens	SERUM ALBUMIN	Serum_albumin	5	PHE A 228 PHE A 309 MET A 329 TYR A 332 GLU A 333	CPT A 602		Details
4YEO_A_CPTA201	4yeo	CPT	Cisplatin (DB00515)	Gallus gallus	LYSOZYME C	Lys	3	ARG A  14 HIS A  15 THR A  89	CPT A 201		Details
5ERJ_A_CPTA218	5erj	CPT	Cisplatin (DB00515)	Equus caballus	FERRITIN LIGHT CHAIN	Ferritin	4	ARG A  64 SER A 131 HIS A 132 GLU A 136	CPT A 218		Details
5I0A_A_CPTA501	5i0a	CPT	Cisplatin (DB00515)	Mycobacterium tuberculosis	INTEIN	NA	3	HIS A 429 HIS A 439 CYS A 441	CPT A 501		Details
5I0A_A_CPTA502	5i0a	CPT	Cisplatin (DB00515)	Mycobacterium tuberculosis	INTEIN	NA	5	CYS A   1 THR A  70 ASP A  72 HIS A  73 ASP A 422	CPT A 502		Details
5L4R_A_CPTA504	5l4r	CPT	Cisplatin (DB00515)	Thaumatococcus daniellii	THAUMATIN-1	Thaumatin	6	GLY A  81 PRO A  83 LYS A 106 CYS A 149 THR A 150 GLN A 153	CPT A 504		Details
5L4R_A_CPTA506	5l4r	CPT	Cisplatin (DB00515)	Thaumatococcus daniellii	THAUMATIN-1	Thaumatin	4	GLY A  47 LYS A  49 PHE A  80 GLU A  89	CPT A 506		Details
5L4R_A_CPTA507	5l4r	CPT	Cisplatin (DB00515)	Thaumatococcus daniellii	THAUMATIN-1	Thaumatin	4	LYS A  97 THR A 192 CYS A 193 PRO A 194	CPT A 507		Details
5L4R_A_CPTA510	5l4r	CPT	Cisplatin (DB00515)	Thaumatococcus daniellii	THAUMATIN-1	Thaumatin	4	ASN A  40 VAL A  41 GLU A  42 PRO A  43	CPT A 510		Details
5L4R_A_CPTA513	5l4r	CPT	Cisplatin (DB00515)	Thaumatococcus daniellii	THAUMATIN-1	Thaumatin	3	LYS A  19 ASP A  21 ALA A  22	CPT A 513		Details
5N26_A_CPTA201	5n26	CPT	Cisplatin (DB00515)	Homo sapiens	FERRITIN HEAVY CHAIN	Ferritin	3	LYS A  68 THR A 135 HIS A 136	CPT A 201		Details
5N26_A_CPTA203	5n26	CPT	Cisplatin (DB00515)	Homo sapiens	FERRITIN HEAVY CHAIN	Ferritin	7	ASP A  89 CYS A  90 TRP A  93 ASN A  98 GLU A 101 CYS A 102 HIS A 105	CPT A 203		Details
5N26_A_CPTA204	5n26	CPT	Cisplatin (DB00515)	Homo sapiens	FERRITIN HEAVY CHAIN	Ferritin	7	ASP A  89 CYS A  90 ASP A  91 ASP A  92 TRP A  93 ASN A  98 CYS A 102	CPT A 204		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2AEO_A_CPTA284","2aeo","CPT","Cisplatin (DB00515)","Bos taurus","SUPEROXIDE DISMUTASE [CU-ZN]","Sod_Cu",4,"THR A 17;HIS A 19;GLY A 31;SER A 32","CPT A 284\r"],["3IWX_A_CPTA69","3iwx","CPT","Cisplatin (DB00515)","Homo sapiens","COPPER TRANSPORT PROTEIN ATOX1","HMA",8,"THR B 11;THR A 11;CYS A 12;CYS B 12;GLY A 13;GLY B 14;CYS B 15;CYS A 15","CPT A 69\r"],["3RE0_B_CPTB201","3re0","CPT","Cisplatin (DB00515)","Homo sapiens","SUPEROXIDE DISMUTASE [CU-ZN]","Sod_Cu",11,"LEU B 106;LEU A 106;SER A 107;SER B 107;GLY B 108;CYS B 111;CYS A 111;ILE B 113;ILE A 113;ILE A 151;ILE B 151","CPT B 201\r"],["4N0Z_A_CPTA203","4n0z","CPT","Cisplatin (DB00515)","Plasmodium falciparum","GLUTAREDOXIN","Glutaredoxin",3,"ASN A 19;MET A 48;HIS A 49","CPT A 203\r"],["4OT4_A_CPTA200","4ot4","CPT","Cisplatin (DB00515)","Bos taurus","RIBONUCLEASE PANCREATIC","RnaseA",5,"GLN A 28;MET A 29;SER A 32;ASP B 53;ALA B 56","CPT A 200\r"],["4OT4_A_CPTA201","4ot4","CPT","Cisplatin (DB00515)","Bos taurus","RIBONUCLEASE PANCREATIC","RnaseA",6,"ASP A 14;SER A 16;TYR A 25;MET A 29;ALA B 56;SER B 59","CPT A 201\r"],["4RSZ_A_CPTA202","4rsz","CPT","Cisplatin (DB00515)","Equus caballus","CYTOCHROME C","Cytochrom_C",4,"GLU A 61;MET A 65;LYS A 88;GLU A 92","CPT A 202\r"],["4S1Y_A_CPTA602","4s1y","CPT","Cisplatin (DB00515)","Homo sapiens","SERUM ALBUMIN","Serum_albumin",5,"PHE A 228;PHE A 309;MET A 329;TYR A 332;GLU A 333","CPT A 602\r"],["4YEO_A_CPTA201","4yeo","CPT","Cisplatin (DB00515)","Gallus gallus","LYSOZYME C","Lys",3,"ARG A 14;HIS A 15;THR A 89","CPT A 201\r"],["5ERJ_A_CPTA218","5erj","CPT","Cisplatin (DB00515)","Equus caballus","FERRITIN LIGHT CHAIN","Ferritin",4,"ARG A 64;SER A 131;HIS A 132;GLU A 136","CPT A 218\r"],["5I0A_A_CPTA501","5i0a","CPT","Cisplatin (DB00515)","Mycobacterium tuberculosis","INTEIN","NA",3,"HIS A 429;HIS A 439;CYS A 441","CPT A 501\r"],["5I0A_A_CPTA502","5i0a","CPT","Cisplatin (DB00515)","Mycobacterium tuberculosis","INTEIN","NA",5,"CYS A 1;THR A 70;ASP A 72;HIS A 73;ASP A 422","CPT A 502\r"],["5L4R_A_CPTA504","5l4r","CPT","Cisplatin (DB00515)","Thaumatococcus daniellii","THAUMATIN-1","Thaumatin",6,"GLY A 81;PRO A 83;LYS A 106;CYS A 149;THR A 150;GLN A 153","CPT A 504\r"],["5L4R_A_CPTA506","5l4r","CPT","Cisplatin (DB00515)","Thaumatococcus daniellii","THAUMATIN-1","Thaumatin",4,"GLY A 47;LYS A 49;PHE A 80;GLU A 89","CPT A 506\r"],["5L4R_A_CPTA507","5l4r","CPT","Cisplatin (DB00515)","Thaumatococcus daniellii","THAUMATIN-1","Thaumatin",4,"LYS A 97;THR A 192;CYS A 193;PRO A 194","CPT A 507\r"],["5L4R_A_CPTA510","5l4r","CPT","Cisplatin (DB00515)","Thaumatococcus daniellii","THAUMATIN-1","Thaumatin",4,"ASN A 40;VAL A 41;GLU A 42;PRO A 43","CPT A 510\r"],["5L4R_A_CPTA513","5l4r","CPT","Cisplatin (DB00515)","Thaumatococcus daniellii","THAUMATIN-1","Thaumatin",3,"LYS A 19;ASP A 21;ALA A 22","CPT A 513\r"],["5N26_A_CPTA201","5n26","CPT","Cisplatin (DB00515)","Homo sapiens","FERRITIN HEAVY CHAIN","Ferritin",3,"LYS A 68;THR A 135;HIS A 136","CPT A 201\r"],["5N26_A_CPTA203","5n26","CPT","Cisplatin (DB00515)","Homo sapiens","FERRITIN HEAVY CHAIN","Ferritin",7,"ASP A 89;CYS A 90;TRP A 93;ASN A 98;GLU A 101;CYS A 102;HIS A 105","CPT A 203\r"],["5N26_A_CPTA204","5n26","CPT","Cisplatin (DB00515)","Homo sapiens","FERRITIN HEAVY CHAIN","Ferritin",7,"ASP A 89;CYS A 90;ASP A 91;ASP A 92;TRP A 93;ASN A 98;CYS A 102","CPT A 204\r"]]