Ligand ID: AMR

Drugbank ID:
Amiloride
(DB00594)

Indication:
Amiloride is a pyrizine compound used to treat hypertension and congestive heart failure.

LIST OF BINDING INTERFACES for query 'DB00594'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1F5L_A_AMRA301	1f5l	AMR	Amiloride (DB00594)	Homo sapiens	UROKINASE-TYPE PLASMINOGEN ACTIVATOR	Trypsin	15	ASP A 189 SER A 190 CYS A 191 GLN A 192 SER A 195 VAL A 213 SER A 214 TRP A 215 GLY A 216 GLY A 219 CYS A 220 ALA A 221 LYS A 224 PRO A 225 GLY A 226	AMR A 301		Details
4NTX_A_AMRA507	4ntx	AMR	Amiloride (DB00594)	Gallus gallus; micrurus tener tener	ACID-SENSING ION CHANNEL 1	ASC	3	ALA A 428 GLY A 429 GLY A 432	AMR A 507		Details
4NTX_A_AMRA508	4ntx	AMR	Amiloride (DB00594)	Gallus gallus; micrurus tener tener	ACID-SENSING ION CHANNEL 1; BASIC PHOSPHOLIPASE A2 HOMOLOG TX-BETA	ASC Phospholip_A2_1	3	ASN C  83 GLU A 236 GLU A 354	AMR A 508		Details
4NTX_A_AMRA509	4ntx	AMR	Amiloride (DB00594)	Gallus gallus; micrurus tener tener	ACID-SENSING ION CHANNEL 1; BASIC PHOSPHOLIPASE A2 HOMOLOG TX-BETA	ASC Phospholip_A2_1	8	ASN C  83 THR C  84 ARG C  87 GLU A 236 THR A 237 ASP A 238 ASP A 350 GLU A 354	AMR A 509		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1F5L_A_AMRA301","1f5l","AMR","Amiloride (DB00594)","Homo sapiens","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","Trypsin",15,"ASP A 189;SER A 190;CYS A 191;GLN A 192;SER A 195;VAL A 213;SER A 214;TRP A 215;GLY A 216;GLY A 219;CYS A 220;ALA A 221;LYS A 224;PRO A 225;GLY A 226","AMR A 301\r"],["4NTX_A_AMRA507","4ntx","AMR","Amiloride (DB00594)","Gallus gallus;micrurus tener tener","ACID-SENSING ION CHANNEL 1","ASC",3,"ALA A 428;GLY A 429;GLY A 432","AMR A 507\r"],["4NTX_A_AMRA508","4ntx","AMR","Amiloride (DB00594)","Gallus gallus;micrurus tener tener","ACID-SENSING ION CHANNEL 1;BASIC PHOSPHOLIPASE A2 HOMOLOG TX-BETA","ASC;Phospholip_A2_1",3,"ASN C 83;GLU A 236;GLU A 354","AMR A 508\r"],["4NTX_A_AMRA509","4ntx","AMR","Amiloride (DB00594)","Gallus gallus;micrurus tener tener","ACID-SENSING ION CHANNEL 1;BASIC PHOSPHOLIPASE A2 HOMOLOG TX-BETA","ASC;Phospholip_A2_1",8,"ASN C 83;THR C 84;ARG C 87;GLU A 236;THR A 237;ASP A 238;ASP A 350;GLU A 354","AMR A 509\r"]]