Ligand ID: GZX

Drugbank ID:
Ixabepilone
(DB04845)


Indication:
Ixabepilone is a microtubule inhibitor administered in combination with capecitabine or alone in the treatment of metastatic or locally advanced breast cancer that has shown inadequate response to taxanes and anthracyclines.


LIST OF BINDING INTERFACES for query 'GZX'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
7DAF_D_GZXD5037daf GZXIxabepilone
(DB04845)
Mus musculus;
gallus gallus;
sus scrofa
TUBULIN BETA CHAIN Tubulin
Tubulin_C
16LEU D 215
LEU D 217
ASP D 224
HIS D 227
LEU D 228
ALA D 231
PHE D 270
PRO D 272
LEU D 273
THR D 274
SER D 275
ARG D 276
GLN D 279
ARG D 282
LEU D 284
LEU D 369
GZX D 503
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details