Ligand ID: JN3

Drugbank ID:
Chenodeoxycholic acid
(DB06777)

Indication:
Chenodeoxycholic acid is a bile acid used for the treatment of primary biliary cirrhosis.

LIST OF BINDING INTERFACES for query 'JN3'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2JN3_A_JN3A130	2jn3	JN3	Chenodeoxycholic acid (DB06777)	Gallus gallus	FATTY ACID-BINDING PROTEIN, LIVER	Lipocalin	32	GLN A  11 TYR A  14 PHE A  17 LEU A  18 LEU A  21 LEU A  23 PRO A  24 LEU A  27 ILE A  28 MET A  30 ALA A  31 ARG A  32 ILE A  34 LYS A  35 PRO A  36 VAL A  38 SER A  51 THR A  53 PRO A  54 ARG A  55 GLN A  56 THR A  72 MET A  73 ASP A  74 GLY A  75 LYS A  76 HIS A  98 GLU A 109 ILE A 111 PHE A 113 LEU A 118 ARG A 120	JN3 A 130		Details
2JN3_A_JN3A131	2jn3	JN3	Chenodeoxycholic acid (DB06777)	Gallus gallus	FATTY ACID-BINDING PROTEIN, LIVER	Lipocalin	32	PHE A   2 PHE A  17 LEU A  21 LEU A  23 VAL A  38 ILE A  40 PHE A  47 VAL A  49 SER A  51 ASN A  60 PHE A  62 ILE A  70 THR A  71 THR A  72 MET A  73 ASP A  74 LYS A  76 LEU A  78 CYS A  80 VAL A  82 LEU A  89 THR A  91 SER A  93 LYS A  95 PHE A  96 SER A  97 HIS A  98 GLN A 100 GLU A 109 ILE A 111 PHE A 113 ARG A 120	JN3 A 131		Details
3O02_B_JN3B1	3o02	JN3	Chenodeoxycholic acid (DB06777)	Salmonella enterica	CELL INVASION PROTEIN SIPD	NA	12	ARG A  41 ILE A  45 ASN B 104 ALA B 108 SER B 317 LEU B 318 ASN B 321 LEU B 322 VAL B 325 ALA A 337 LYS A 338 PHE A 340	JN3 B   1		Details
6HL1_A_JN3A501	6hl1	JN3	Chenodeoxycholic acid (DB06777)	Homo sapiens; synthetic construct	BILE ACID RECEPTOR	Hormone_recep	20	MET A 265 LEU A 287 MET A 290 ALA A 291 HIS A 294 MET A 328 PHE A 329 ARG A 331 SER A 332 ILE A 335 PHE A 336 LEU A 348 ILE A 352 ILE A 357 TYR A 361 TYR A 369 HIS A 447 MET A 450 TRP A 454 TRP A 469	JN3 A 501		Details
6IE9_A_JN3A200	6ie9	JN3	Chenodeoxycholic acid (DB06777)	Salmonella typhimurium (strain 14028s / sgsc 2262)	REGULATORY PROTEIN	TetR_N	18	TYR A  59 LYS A  63 LEU A  66 MET A  70 ALA A  81 THR A  85 ILE A  88 TYR A  92 ILE A 106 ALA A 110 ARG A 136 SER A 137 LEU A 139 MET A 140 ARG A 148 ASP A 152 PHE A 155 LEU A 156	JN3 A 200		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2JN3_A_JN3A130","2jn3","JN3","Chenodeoxycholic acid (DB06777)","Gallus gallus","FATTY ACID-BINDING PROTEIN, LIVER","Lipocalin",32,"GLN A 11;TYR A 14;PHE A 17;LEU A 18;LEU A 21;LEU A 23;PRO A 24;LEU A 27;ILE A 28;MET A 30;ALA A 31;ARG A 32;ILE A 34;LYS A 35;PRO A 36;VAL A 38;SER A 51;THR A 53;PRO A 54;ARG A 55;GLN A 56;THR A 72;MET A 73;ASP A 74;GLY A 75;LYS A 76;HIS A 98;GLU A 109;ILE A 111;PHE A 113;LEU A 118;ARG A 120","JN3 A 130\r"],["2JN3_A_JN3A131","2jn3","JN3","Chenodeoxycholic acid (DB06777)","Gallus gallus","FATTY ACID-BINDING PROTEIN, LIVER","Lipocalin",32,"PHE A 2;PHE A 17;LEU A 21;LEU A 23;VAL A 38;ILE A 40;PHE A 47;VAL A 49;SER A 51;ASN A 60;PHE A 62;ILE A 70;THR A 71;THR A 72;MET A 73;ASP A 74;LYS A 76;LEU A 78;CYS A 80;VAL A 82;LEU A 89;THR A 91;SER A 93;LYS A 95;PHE A 96;SER A 97;HIS A 98;GLN A 100;GLU A 109;ILE A 111;PHE A 113;ARG A 120","JN3 A 131\r"],["3O02_B_JN3B1","3o02","JN3","Chenodeoxycholic acid (DB06777)","Salmonella enterica","CELL INVASION PROTEIN SIPD","NA",12,"ARG A 41;ILE A 45;ASN B 104;ALA B 108;SER B 317;LEU B 318;ASN B 321;LEU B 322;VAL B 325;ALA A 337;LYS A 338;PHE A 340","JN3 B 1\r"],["6HL1_A_JN3A501","6hl1","JN3","Chenodeoxycholic acid (DB06777)","Homo sapiens;synthetic construct","BILE ACID RECEPTOR","Hormone_recep",20,"MET A 265;LEU A 287;MET A 290;ALA A 291;HIS A 294;MET A 328;PHE A 329;ARG A 331;SER A 332;ILE A 335;PHE A 336;LEU A 348;ILE A 352;ILE A 357;TYR A 361;TYR A 369;HIS A 447;MET A 450;TRP A 454;TRP A 469","JN3 A 501\r"],["6IE9_A_JN3A200","6ie9","JN3","Chenodeoxycholic acid (DB06777)","Salmonella typhimurium (strain 14028s \/ sgsc 2262)","REGULATORY PROTEIN","TetR_N",18,"TYR A 59;LYS A 63;LEU A 66;MET A 70;ALA A 81;THR A 85;ILE A 88;TYR A 92;ILE A 106;ALA A 110;ARG A 136;SER A 137;LEU A 139;MET A 140;ARG A 148;ASP A 152;PHE A 155;LEU A 156","JN3 A 200\r"]]