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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 1jt6 | DEQ | Dequalinium (DB04209) | Dequalinium is a quaternary ammonium cation antimicrobial agent used to treat common infections of the mouth and throat that has been studied in the treatment of vaginal candidiasis. | HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION (Staphylococcus aureus) | TetR_C_5TetR_N | ||
| 1jtx | CVI | Gentian violet cation (DB00406) | Gentian Violet is an antiseptic violet dye used to prevent various infections, including fungal and bacterial infections. | HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION (Staphylococcus aureus) | TetR_C_5TetR_N | ||
| 1qvt | PRL | Proflavine (DB01123) | Proflavine is a topical antiseptic agent used in wound dressings to prevent infections. | TRANSCRIPTIONAL REGULATOR QACR (Staphylococcus aureus) | TetR_C_5TetR_N | ||
| 1rkw | PNT | Pentamidine (DB00738) | Pentamidine is an antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV. | TRANSCRIPTIONAL REGULATOR QACR (Staphylococcus aureus) | TetR_C_5TetR_N | ||
| 2uxo | TAC | Tetracycline (DB00759) | Tetracycline is an antibiotic used to treat a wide variety of susceptible infections. | HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR (Pseudomonas putida) | TetR_C_2TetR_N | ||
| 2uxp | CLM | Chloramphenicol (DB00446) | Chloramphenicol is a broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity. | HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGR (Pseudomonas putida) | TetR_C_2TetR_N | ||
| 3bpx | SAL | Salicylic acid (DB00936) | Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. | TRANSCRIPTIONAL REGULATOR (Methanobacterium thermoautotrophicum) | MarR | ||
| 3bti | BER | Berberine (DB04115) | An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal... | HTH-TYPE TRANSCRIPTIONAL REGULATOR QACR (Staphylococcus aureus) | TetR_C_5TetR_N | ||
| 3deu | SAL | Salicylic acid (DB00936) | Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. | TRANSCRIPTIONAL REGULATOR SLYA (Salmonella typhimurium) | MarR | ||
| 3f8f | DM1 | Daunorubicin (DB00694) | Daunorubicin is an anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia. | TRANSCRIPTIONAL REGULATOR, PADR-LIKE FAMILY (Lactococcus lactis subsp. cremoris) | PadR | ||
| 3gf2 | SAL | Salicylic acid (DB00936) | Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. | 146AA LONG HYPOTHETICAL TRANSCRIPTIONAL REGULATOR (Sulfolobus tokodaii) | MarR_2 | ||
| 3kp2 | PNN | Benzylpenicillin (DB01053) | Benzylpenicillin is a penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption. | TRANSCRIPTIONAL REGULATOR TCAR (Staphylococcus epidermidis rp62a) | MarR_2 | ||
| 3kp3 | AIC | Ampicillin (DB00415) | Ampicillin is a penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes. | TRANSCRIPTIONAL REGULATOR TCAR (Staphylococcus epidermidis rp62a) | MarR_2 | ||
| 3kp5 | KAN | Kanamycin (DB01172) | Kanamycin is an aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria. | TRANSCRIPTIONAL REGULATOR TCAR (Staphylococcus epidermidis rp62a) | MarR_2 | ||
| 3kp6 | SAL | Salicylic acid (DB00936) | Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. | TRANSCRIPTIONAL REGULATOR TCAR (Staphylococcus epidermidis rp62a) | MarR_2 | ||
| 3zmd | SAL | Salicylic acid (DB00936) | Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. | PUTATIVE TRANSCRIPTIONAL REGULATOR (Streptomyces coelicolor) | MarR_2 | ||
| 4ejw | SRY | Streptomycin (DB01082) | Streptomycin is an aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections. | TRANSCRIPTIONAL REGULATOR TCAR (Staphylococcus epidermidis rp62a) | MarR_2 | ||
| 4em0 | KAN | Kanamycin (DB01172) | Kanamycin is an aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria. | UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349 (Staphylococcus aureus) | MarR | ||
| 4em2 | SAL | Salicylic acid (DB00936) | Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. | UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349 (Staphylococcus aureus) | MarR | ||
| 5nz0 | ZLD | Linezolid (DB00601) | Linezolid is an oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria. | HTH-TYPE TRANSCRIPTIONAL REGULATOR ETHR (Mycobacterium tuberculosis) | TetR_N | ||
| 5x03 | ABU | Gamma-aminobutyric acid (DB02530) | The most common inhibitory neurotransmitter in the central nervous system. | HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR (Bacillus subtilis (strain 168)) | Aminotran_1_2 | ||
| 5x7z | BHA | Aminosalicylic acid (DB00233) | Aminosalicylic acid is an aminosalicylate drug used to induce remission in ulcerative colitis. | UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887 (Mycobacterium tuberculosis h37rv) | MarR | ||
| 5x80 | SAL | Salicylic acid (DB00936) | Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. | UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887 (Mycobacterium tuberculosis h37rv) | MarR | ||
| 6wl5 | 16A | Cetrimonium (DB01718) | Cetrimonium is a compound that can be used as a topical antiseptic. | ECMRR TRANSCRIPTIONAL REGULATOR (Escherichia coli) | NA | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |