Results: Ligand

Ligand ID: PNN

Drugbank ID:
Benzylpenicillin
(DB01053)

Indication:
Benzylpenicillin is a penicillin used for the treatment of infections caused by gram-positive cocci, in particular streptococcal infections. This form of penicillin is typically used in intravenous or long-acting injectable formulations due to poor oral absorption.

LIST OF BINDING INTERFACES for query 'DB01053'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1GM7_B_PNNB1577	1gm7	PNN	Benzylpenicillin (DB01053)	Escherichia coli	PENICILLIN G ACYLASE ALPHA SUBUNIT; PENICILLIN G ACYLASE BETA SUBUNIT	NA	13	SER B 1 PRO B 22 GLN B 23 PHE B 24 SER B 67 THR B 68 ALA B 69 PHE B 71 MET A 142 ARG A 145 PHE A 146 SER A 149 ILE B 177	PNN B1577
1UOF_A_PNNA1312	1uof	PNN	Benzylpenicillin (DB01053)	Streptomyces clavuligerus	DEACETOXYCEPHALOSPORIN C SYNTHETASE	2OG-FeII_Oxy DIOX_N	17	PHE A 164 ARG A 179 MET A 180 HIS A 183 ASP A 185 THR A 190 ILE A 192 SER A 203 LEU A 204 PHE A 225 HIS A 243 VAL A 245 ARG A 258 SER A 260 VAL A 262 PHE A 264 ILE A 305	PNN A1312
3HUO_A_PNNA300	3huo	PNN	Benzylpenicillin (DB01053)	Escherichia coli	CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE	Beta-lactamase2	14	CYS A 69 GLY A 70 LYS A 73 ASN A 104 TYR A 105 SER A 130 ASN A 132 ASN A 170 LYS A 234 THR A 235 GLY A 236 SER A 237 GLY A 238 ASP A 240	PNN A 300
3HUO_A_PNNA302	3huo	PNN	Benzylpenicillin (DB01053)	Escherichia coli	CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE	Beta-lactamase2	8	THR A 51 GLN A 188 ARG A 191 GLN A 192 LEU A 195 GLY A 196 ALA A 257 PRO A 258	PNN A 302
3HUO_A_PNNA303	3huo	PNN	Benzylpenicillin (DB01053)	Escherichia coli	CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE	Beta-lactamase2	5	GLN A 188 GLN A 192 GLY A 196 HIS A 197 ALA A 198	PNN A 303
3HUO_A_PNNA304	3huo	PNN	Benzylpenicillin (DB01053)	Escherichia coli	CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE	Beta-lactamase2	4	GLN A 93 PRO A 94 VAL A 95 GLU A 96	PNN A 304
3KP2_A_PNNA5001	3kp2	PNN	Benzylpenicillin (DB01053)	Staphylococcus epidermidis rp62a	TRANSCRIPTIONAL REGULATOR TCAR	MarR_2	10	ASN A 20 ASN B 20 THR A 23 LEU A 27 GLN A 31 ALA A 38 GLU A 39 SER A 41 HIS A 42 ARG A 110	PNN A5001
5KMW_A_PNNA305	5kmw	PNN	Benzylpenicillin (DB01053)	Escherichia coli	BETA-LACTAMASE TOHO-1	Beta-lactamase2	5	ASN A 103 PRO A 166 ASN A 169 THR A 170 ASP A 238	PNN A 305
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1GM7_B_PNNB1577","1gm7","PNN","Benzylpenicillin (DB01053)","Escherichia coli","PENICILLIN G ACYLASE ALPHA SUBUNIT;PENICILLIN G ACYLASE BETA SUBUNIT","NA",13,"SER B   1;PRO B  22;GLN B  23;PHE B  24;SER B  67;THR B  68;ALA B  69;PHE B  71;MET A 142;ARG A 145;PHE A 146;SER A 149;ILE B 177","PNN B1577\r"],["1UOF_A_PNNA1312","1uof","PNN","Benzylpenicillin (DB01053)","Streptomyces clavuligerus","DEACETOXYCEPHALOSPORIN C SYNTHETASE","2OG-FeII_Oxy;DIOX_N",17,"PHE A 164;ARG A 179;MET A 180;HIS A 183;ASP A 185;THR A 190;ILE A 192;SER A 203;LEU A 204;PHE A 225;HIS A 243;VAL A 245;ARG A 258;SER A 260;VAL A 262;PHE A 264;ILE A 305","PNN A1312\r"],["3HUO_A_PNNA300","3huo","PNN","Benzylpenicillin (DB01053)","Escherichia coli","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","Beta-lactamase2",14,"CYS A  69;GLY A  70;LYS A  73;ASN A 104;TYR A 105;SER A 130;ASN A 132;ASN A 170;LYS A 234;THR A 235;GLY A 236;SER A 237;GLY A 238;ASP A 240","PNN A 300\r"],["3HUO_A_PNNA302","3huo","PNN","Benzylpenicillin (DB01053)","Escherichia coli","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","Beta-lactamase2",8,"THR A  51;GLN A 188;ARG A 191;GLN A 192;LEU A 195;GLY A 196;ALA A 257;PRO A 258","PNN A 302\r"],["3HUO_A_PNNA303","3huo","PNN","Benzylpenicillin (DB01053)","Escherichia coli","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","Beta-lactamase2",5,"GLN A 188;GLN A 192;GLY A 196;HIS A 197;ALA A 198","PNN A 303\r"],["3HUO_A_PNNA304","3huo","PNN","Benzylpenicillin (DB01053)","Escherichia coli","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","Beta-lactamase2",4,"GLN A  93;PRO A  94;VAL A  95;GLU A  96","PNN A 304\r"],["3KP2_A_PNNA5001","3kp2","PNN","Benzylpenicillin (DB01053)","Staphylococcus epidermidis rp62a","TRANSCRIPTIONAL REGULATOR TCAR","MarR_2",10,"ASN A  20;ASN B  20;THR A  23;LEU A  27;GLN A  31;ALA A  38;GLU A  39;SER A  41;HIS A  42;ARG A 110","PNN A5001\r"],["5KMW_A_PNNA305","5kmw","PNN","Benzylpenicillin (DB01053)","Escherichia coli","BETA-LACTAMASE TOHO-1","Beta-lactamase2",5,"ASN A 103;PRO A 166;ASN A 169;THR A 170;ASP A 238","PNN A 305\r"]]