Results: Ligand

Ligand ID: PRL

Drugbank ID:
Proflavine
(DB01123)

Indication:
Proflavine is a topical antiseptic agent used in wound dressings to prevent infections.

LIST OF BINDING INTERFACES for query 'PRL'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1BCU_H_PRLH280	1bcu	PRL	Proflavine (DB01123)	Hirudo medicinalis; homo sapiens	ALPHA-THROMBIN	Trypsin	12	ASP H 189 ALA H 190 CYS H 191 GLU H 192 SER H 195 VAL H 213 SER H 214 TRP H 215 GLY H 216 GLY H 219 CYS H 220 GLY H 226	PRL H 280
1QVT_A_PRLA311	1qvt	PRL	Proflavine (DB01123)	Staphylococcus aureus	TRANSCRIPTIONAL REGULATOR QACR	TetR_C_5 TetR_N	10	LEU A 54 GLU A 57 GLU A 58 TRP A 61 THR A 89 GLU A 90 TYR A 93 ILE A 99 TYR A 103 LEU A 119	PRL A 311
2V57_A_PRLA1188	2v57	PRL	Proflavine (DB01123)	Mycobacterium smegmatis	TETR FAMILY TRANSCRIPTIONAL REPRESSOR LFRR	TetR_N	12	HIS A 67 SER A 70 ASN A 71 ILE A 74 TYR A 106 PHE A 121 ASP A 122 ILE A 123 GLY A 124 ASP A 125 ARG A 148 TRP A 152	PRL A1188
3HTH_A_PRLA201	3hth	PRL	Proflavine (DB01123)	Streptomyces lividans	EBRA REPRESSOR	TetR_C_31 TetR_N	13	GLY A 66 PHE A 67 VAL A 70 VAL A 91 LEU A 92 TRP A 95 GLU A 106 TYR A 107 TYR A 110 TRP A 126 LEU A 150 ASP A 151 CYS A 154	PRL A 201
4ZPH_A_PRLA501	4zph	PRL	Proflavine (DB01123)	Mus musculus	ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1	HLH PAS PAS_3	7	ARG A 266 VAL A 305 GLN B 306 TRP B 318 LEU B 344 SER B 345 GLU B 348	PRL A 501
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1BCU_H_PRLH280","1bcu","PRL","Proflavine (DB01123)","Hirudo medicinalis;homo sapiens","ALPHA-THROMBIN","Trypsin",12,"ASP H 189;ALA H 190;CYS H 191;GLU H 192;SER H 195;VAL H 213;SER H 214;TRP H 215;GLY H 216;GLY H 219;CYS H 220;GLY H 226","PRL H 280\r"],["1QVT_A_PRLA311","1qvt","PRL","Proflavine (DB01123)","Staphylococcus aureus","TRANSCRIPTIONAL REGULATOR QACR","TetR_C_5;TetR_N",10,"LEU A  54;GLU A  57;GLU A  58;TRP A  61;THR A  89;GLU A  90;TYR A  93;ILE A  99;TYR A 103;LEU A 119","PRL A 311\r"],["2V57_A_PRLA1188","2v57","PRL","Proflavine (DB01123)","Mycobacterium smegmatis","TETR FAMILY TRANSCRIPTIONAL REPRESSOR LFRR","TetR_N",12,"HIS A  67;SER A  70;ASN A  71;ILE A  74;TYR A 106;PHE A 121;ASP A 122;ILE A 123;GLY A 124;ASP A 125;ARG A 148;TRP A 152","PRL A1188\r"],["3HTH_A_PRLA201","3hth","PRL","Proflavine (DB01123)","Streptomyces lividans","EBRA REPRESSOR","TetR_C_31;TetR_N",13,"GLY A  66;PHE A  67;VAL A  70;VAL A  91;LEU A  92;TRP A  95;GLU A 106;TYR A 107;TYR A 110;TRP A 126;LEU A 150;ASP A 151;CYS A 154","PRL A 201\r"],["4ZPH_A_PRLA501","4zph","PRL","Proflavine (DB01123)","Mus musculus","ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR;ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1","HLH;PAS;PAS_3",7,"ARG A 266;VAL A 305;GLN B 306;TRP B 318;LEU B 344;SER B 345;GLU B 348","PRL A 501\r"]]