Results: Ligand

Ligand ID: AIC

Drugbank ID:
Ampicillin
(DB00415)

Indication:
Ampicillin is a penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes.

LIST OF BINDING INTERFACES for query 'DB00415'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1H8S_A_AICA1000	1h8s	AIC	Ampicillin (DB00415)	Mus musculus	MUTANT AL2 6E7P9G	NA	15	TYR A 39 GLN A 92 TYR A 94 TYR A 97 LEU A 99 PHE A 101 TRP A 164 ASN A 166 VAL A 168 TRP A 178 ASN A 181 ALA A 228 ARG A 229 TRP A 230 TRP A 233	AIC A1000
1NX9_A_AICA5001	1nx9	AIC	Ampicillin (DB00415)	Acetobacter pasteurianus	ALPHA-AMINO ACID ESTER HYDROLASE	PepX_C Peptidase_S15	10	TYR A 112 ARG A 117 TYR A 154 ALA A 205 GLU A 207 SER A 256 GLN A 257 HIS A 370 SER A 371 TYR A 375	AIC A5001
2RDD_A_AICA1109	2rdd	AIC	Ampicillin (DB00415)	Escherichia coli	ACRIFLAVINE RESISTANCE PROTEIN B	ACR_tran	5	SER A 96 GLY A 97 PHE A 458 GLY A 460 ARG A 468	AIC A1109
2RDD_A_AICA1110	2rdd	AIC	Ampicillin (DB00415)	Escherichia coli	ACRIFLAVINE RESISTANCE PROTEIN B	ACR_tran	5	LYS A 29 ALA A 384 ALA A 385 PHE A 386 GLY A 387	AIC A1110
3ITA_D_AICD501	3ita	AIC	Ampicillin (DB00415)	Escherichia coli	D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACC	PBP5_C Peptidase_S11	9	PRO D 264 ILE D 265 PHE D 271 VAL D 272 LEU D 304 LYS D 305 ALA D 306 TYR D 308 PHE D 330	AIC D 501
3KP3_B_AICB2001	3kp3	AIC	Ampicillin (DB00415)	Staphylococcus epidermidis rp62a	TRANSCRIPTIONAL REGULATOR TCAR	MarR_2	14	GLU A 13 ASN B 20 THR B 23 ALA B 24 LEU B 27 GLN B 31 ALA B 38 GLU B 39 SER B 41 HIS B 42 ASN B 45 GLN B 61 TYR B 106 ARG B 110	AIC B2001
3KP3_B_AICB2002	3kp3	AIC	Ampicillin (DB00415)	Staphylococcus epidermidis rp62a	TRANSCRIPTIONAL REGULATOR TCAR	MarR_2	4	ALA B 66 SER B 69 ARG B 70 LYS B 74	AIC B2002
3NDV_A_AICA375	3ndv	AIC	Ampicillin (DB00415)	Sphingosinicella xenopeptidilytica	BETA-PEPTIDYL AMINOPEPTIDASE	Peptidase_S58	16	THR A 76 GLY A 77 THR A 100 PHE B 124 LEU B 127 LEU B 128 GLU A 133 THR A 134 LEU A 135 ASN A 137 ARG A 138 ASN A 207 SER A 250 LEU A 287 SER A 288 GLY A 289	AIC A 375
4GCP_A_AICA401	4gcp	AIC	Ampicillin (DB00415)	Escherichia coli	OUTER MEMBRANE PROTEIN F	Porin_1	12	TYR A 22 TYR A 32 GLY A 33 PHE A 118 GLY A 119 GLY A 120 ASP A 121 ALA A 123 TYR A 124 SER A 125 ARG A 167 ARG A 168	AIC A 401
4KR4_C_AICC401	4kr4	AIC	Ampicillin (DB00415)	Salmonella enterica subsp. enterica serovar typhi	OUTER MEMBRANE PROTEIN F	Porin_1	15	LYS C 16 ARG C 20 TYR C 36 ARG C 60 ARG C 77 ASP C 108 TYR C 112 PHE C 113 SER C 114 GLY C 115 GLU C 116 GLY C 120 ALA C 121 THR C 123 ARG C 130	AIC C 401
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1H8S_A_AICA1000","1h8s","AIC","Ampicillin (DB00415)","Mus musculus","MUTANT AL2 6E7P9G","NA",15,"TYR A  39;GLN A  92;TYR A  94;TYR A  97;LEU A  99;PHE A 101;TRP A 164;ASN A 166;VAL A 168;TRP A 178;ASN A 181;ALA A 228;ARG A 229;TRP A 230;TRP A 233","AIC A1000\r"],["1NX9_A_AICA5001","1nx9","AIC","Ampicillin (DB00415)","Acetobacter pasteurianus","ALPHA-AMINO ACID ESTER HYDROLASE","PepX_C;Peptidase_S15",10,"TYR A 112;ARG A 117;TYR A 154;ALA A 205;GLU A 207;SER A 256;GLN A 257;HIS A 370;SER A 371;TYR A 375","AIC A5001\r"],["2RDD_A_AICA1109","2rdd","AIC","Ampicillin (DB00415)","Escherichia coli","ACRIFLAVINE RESISTANCE PROTEIN B","ACR_tran",5,"SER A  96;GLY A  97;PHE A 458;GLY A 460;ARG A 468","AIC A1109\r"],["2RDD_A_AICA1110","2rdd","AIC","Ampicillin (DB00415)","Escherichia coli","ACRIFLAVINE RESISTANCE PROTEIN B","ACR_tran",5,"LYS A  29;ALA A 384;ALA A 385;PHE A 386;GLY A 387","AIC A1110\r"],["3ITA_D_AICD501","3ita","AIC","Ampicillin (DB00415)","Escherichia coli","D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACC","PBP5_C;Peptidase_S11",9,"PRO D 264;ILE D 265;PHE D 271;VAL D 272;LEU D 304;LYS D 305;ALA D 306;TYR D 308;PHE D 330","AIC D 501\r"],["3KP3_B_AICB2001","3kp3","AIC","Ampicillin (DB00415)","Staphylococcus epidermidis rp62a","TRANSCRIPTIONAL REGULATOR TCAR","MarR_2",14,"GLU A  13;ASN B  20;THR B  23;ALA B  24;LEU B  27;GLN B  31;ALA B  38;GLU B  39;SER B  41;HIS B  42;ASN B  45;GLN B  61;TYR B 106;ARG B 110","AIC B2001\r"],["3KP3_B_AICB2002","3kp3","AIC","Ampicillin (DB00415)","Staphylococcus epidermidis rp62a","TRANSCRIPTIONAL REGULATOR TCAR","MarR_2",4,"ALA B  66;SER B  69;ARG B  70;LYS B  74","AIC B2002\r"],["3NDV_A_AICA375","3ndv","AIC","Ampicillin (DB00415)","Sphingosinicella xenopeptidilytica","BETA-PEPTIDYL AMINOPEPTIDASE","Peptidase_S58",16,"THR A  76;GLY A  77;THR A 100;PHE B 124;LEU B 127;LEU B 128;GLU A 133;THR A 134;LEU A 135;ASN A 137;ARG A 138;ASN A 207;SER A 250;LEU A 287;SER A 288;GLY A 289","AIC A 375\r"],["4GCP_A_AICA401","4gcp","AIC","Ampicillin (DB00415)","Escherichia coli","OUTER MEMBRANE PROTEIN F","Porin_1",12,"TYR A  22;TYR A  32;GLY A  33;PHE A 118;GLY A 119;GLY A 120;ASP A 121;ALA A 123;TYR A 124;SER A 125;ARG A 167;ARG A 168","AIC A 401\r"],["4KR4_C_AICC401","4kr4","AIC","Ampicillin (DB00415)","Salmonella enterica subsp. enterica serovar typhi","OUTER MEMBRANE PROTEIN F","Porin_1",15,"LYS C  16;ARG C  20;TYR C  36;ARG C  60;ARG C  77;ASP C 108;TYR C 112;PHE C 113;SER C 114;GLY C 115;GLU C 116;GLY C 120;ALA C 121;THR C 123;ARG C 130","AIC C 401\r"]]