
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
---|---|---|---|---|---|---|---|
3l1m | HQI | Oxyquinoline (DB11145) | Oxyquinoline is a medication used in combination with other medications to restore vaginal pH. | SOLUBLE CYTOCHROME B562 (Escherichia coli) | Cytochrom_B562 | ||
4iaq | 2GM | Dihydroergotamine (DB00320) | Dihydroergotamine is an ergot alkaloid used in the acute treatment of migraine headache and cluster headache. | CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 1B AND E. COLI SOLUBLE CYTOCHROME B562 (Homo sapiens;escherichia coli) | 7tm_1Cytochrom_B562 | ||
4iar | ERM | Ergotamine (DB00696) | Ergotamine is a alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. | CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 1B AND E. COLI SOLUBLE CYTOCHROME B562 (Homo sapiens;escherichia coli) | 7tm_1Cytochrom_B562 | ||
4ib4 | ERM | Ergotamine (DB00696) | Ergotamine is a alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. | CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562 (Homo sapiens;escherichia coli) | 7tm_1Cytochrom_B562 | ||
4zud | OLM | Olmesartan (DB00275) | Olmesartan is an angiotensin receptor blocker (ARB) used in the treatment of hypertension. | CHIMERA PROTEIN OF SOLUBLE CYTOCHROME B562 AND TYPE-1 ANGIOTENSIN II RECEPTOR (Escherichia coli;homo sapiens) | 7tm_1Cytochrom_B562 | ||
5l7i | VIS | Vismodegib (DB08828) | Vismodegib is a hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma. | SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG (Homo sapiens;escherichia coli) | FrizzledFz | ||
5mzj | TEP | Theophylline (DB00277) | Theophylline is a xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction. | ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A (Homo sapiens;escherichia coli) | 7tm_1Cytochrom_B562 | ||
5mzp | CFF | Caffeine (DB00201) | Caffeine is a stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth. | ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A (Homo sapiens;escherichia coli) | 7tm_1Cytochrom_B562 | ||
6a93 | 8NU | Risperidone (DB00734) | Risperidone is a second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression. | 5-HYDROXYTRYPTAMINE RECEPTOR 2A,SOLUBLE CYTOCHROME B562 (Homo sapiens;escherichia coli) | 7tm_1Cytochrom_B562 | ||
6a94 | ZOT | Zotepine (DB09225) | Zotepine, with the formula (2-chloro-11-(2-dimethyl-amino-ethoxy)-dibenzo thiepin, is a neuroleptic drug. It was designed and synthesized by Fujisawa Pharmaceutical Co Ltd. It has been used as an antipsychotic in Japan, India... | 5-HYDROXYTRYPTAMINE RECEPTOR 2A,SOLUBLE CYTOCHROME B562 (Homo sapiens;escherichia coli) | 7tm_1Cytochrom_B562 | ||
6ak3 | P2E | Dinoprostone (DB00917) | Dinoprostone is a prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease. | PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE,SOLUBLE CYTOCHROME B562 (Homo sapiens;escherichia coli) | 7tm_1 | ||
6bqg | ERM | Ergotamine (DB00696) | Ergotamine is a alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. | 5-HYDROXYTRYPTAMINE RECEPTOR 2C,SOLUBLE CYTOCHROME B562 (Homo sapiens;escherichia coli) | 7tm_1Cytochrom_B562 | ||
6me9 | JEV | Ramelteon (DB00980) | Ramelteon is a melatonin receptor agonist used to treat insomnia. | SOLUBLE CYTOCHROME B562,MELATONIN RECEPTOR TYPE 1B,RUBREDOXIN (Escherichia coli;homo sapiens;clostridium pasteurianum) | 7tm_1Cytochrom_B562Rubredoxin | ||
6ot4 | HAE | Acetohydroxamic acid (DB00551) | Acetohydroxamic acid is a synthetic urea derivative used to treat urea splitting bacterial infections of the urinary tract. | SOLUBLE CYTOCHROME B562 (Escherichia coli) | Cytochrom_B562 | ||
6pv7 | NCT | Nicotine (DB00184) | Nicotine is a stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation. | FUSION PROTEIN OF NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-3 AND SOLUBLE CYTOCHROME B562;FUSION PROTEIN OF NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-4 AND SOLUBLE CYTOCHROME B562 (Homo sapiens;escherichia coli o11;mus musculus) | Neur_chan_LBDNeur_chan_memb | ||
6rz5 | ZLK | Zafirlukast (DB00549) | Zafirlukast is a leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma. | CYSTEINYL LEUKOTRIENE RECEPTOR 1,SOLUBLE CYTOCHROME B562,CYSTEINYL LEUKOTRIENE RECEPTOR 1 (Homo sapiens;escherichia coli) | 7tm_1 | ||
6ur8 | QMR | Varenicline (DB01273) | Varenicline is a partial agonist at nicotinic acetylcholine receptors used as an aid in smoking cessation. | CHIMERA OF SOLUBLE CYTOCHROME B562 (BRIL) AND NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-4;NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-2 (Homo sapiens;escherichia coli) | Neur_chan_LBDNeur_chan_memb | ||
7cmu | G6L | Pramipexole (DB00413) | Pramipexole is a non-ergot dopamine agonist used to treat the signs and symptoms of idiopathic Parkinson's disease and Restless Legs Syndrome (RLS). | SOLUBLE CYTOCHROME B562,D(3) DOPAMINE RECEPTOR (Homo sapiens;mus musculus;escherichia coli) | 7tm_1Cytochrom_B562 | ||
7e2z | 9SC | Aripiprazole (DB01238) | Aripiprazole is an atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome. | SOLUBLE CYTOCHROME B562,5-HYDROXYTRYPTAMINE RECEPTOR 1A (Homo sapiens;escherichia coli) | 7tm_1Cytochrom_B562 | ||
7jvr | 08Y | Bromocriptine (DB01200) | Bromocriptine is a dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. | SOLUBLE CYTOCHROME B562,D(2) DOPAMINE RECEPTOR (Escherichia coli;homo sapiens;synthetic construct) | 7tm_1 | ||
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |