Ligand ID: VIS

Drugbank ID:
Vismodegib
(DB08828)

Indication:
Vismodegib is a hedgehog pathway inhibitor used to treat patients with locally advanced or metastatic basal cell carcinoma.

LIST OF BINDING INTERFACES for query 'VIS'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
5L7I_A_VISA1202	5l7i	VIS	Vismodegib (DB08828)	Homo sapiens; escherichia coli	SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG	Frizzled Fz	20	ASN A 219 LEU A 221 MET A 230 TRP A 281 ASP A 384 VAL A 386 SER A 387 TYR A 394 ARG A 400 HIS A 470 ASP A 473 GLN A 477 TRP A 480 GLU A 481 PHE A 484 PRO A 513 GLU A 518 ASN A 521 LEU A 522 MET A 525	VIS A1202		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["5L7I_A_VISA1202","5l7i","VIS","Vismodegib (DB08828)","Homo sapiens;escherichia coli","SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG","Frizzled;Fz",20,"ASN A 219;LEU A 221;MET A 230;TRP A 281;ASP A 384;VAL A 386;SER A 387;TYR A 394;ARG A 400;HIS A 470;ASP A 473;GLN A 477;TRP A 480;GLU A 481;PHE A 484;PRO A 513;GLU A 518;ASN A 521;LEU A 522;MET A 525","VIS A1202\r"]]