Ligand ID: ERM

Drugbank ID:
Ergotamine
(DB00696)

Indication:
Ergotamine is a alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches.

LIST OF BINDING INTERFACES for query 'ERM'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4IAR_A_ERMA2001	4iar	ERM	Ergotamine (DB00696)	Homo sapiens; escherichia coli	CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 1B AND E. COLI SOLUBLE CYTOCHROME B562	7tm_1 Cytochrom_B562	22	TYR A 109 TRP A 125 LEU A 126 ASP A 129 ILE A 130 CYS A 133 THR A 134 CYS A 199 VAL A 200 VAL A 201 SER A 212 ALA A 216 TRP A 327 PHE A 330 PHE A 331 SER A 334 MET A 337 LEU A 348 PHE A 351 ASP A 352 THR A 355 TYR A 359	ERM A2001		Details
4IB4_A_ERMA2001	4ib4	ERM	Ergotamine (DB00696)	Homo sapiens; escherichia coli	CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562	7tm_1 Cytochrom_B562	27	TRP A 131 LEU A 132 ASP A 135 VAL A 136 SER A 139 THR A 140 CYS A 207 VAL A 208 LEU A 209 THR A 210 LYS A 211 PHE A 217 MET A 218 GLY A 221 SER A 222 ALA A 225 TRP A 337 PHE A 340 PHE A 341 ASN A 344 LEU A 347 VAL A 348 GLN A 359 LEU A 362 GLU A 363 VAL A 366 TYR A 370	ERM A2001		Details
6BQG_A_ERMA1201	6bqg	ERM	Ergotamine (DB00696)	Homo sapiens; escherichia coli	5-HYDROXYTRYPTAMINE RECEPTOR 2C,SOLUBLE CYTOCHROME B562	7tm_1 Cytochrom_B562	24	TRP A 130 ASP A 134 VAL A 135 SER A 138 THR A 139 CYS A 207 VAL A 208 LEU A 209 PHE A 214 VAL A 215 GLY A 218 SER A 219 ALA A 222 TRP A 324 PHE A 327 PHE A 328 ASN A 331 SER A 334 VAL A 335 GLU A 347 LEU A 350 ASN A 351 VAL A 354 TYR A 358	ERM A1201		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4IAR_A_ERMA2001","4iar","ERM","Ergotamine (DB00696)","Homo sapiens;escherichia coli","CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 1B AND E. COLI SOLUBLE CYTOCHROME B562","7tm_1;Cytochrom_B562",22,"TYR A 109;TRP A 125;LEU A 126;ASP A 129;ILE A 130;CYS A 133;THR A 134;CYS A 199;VAL A 200;VAL A 201;SER A 212;ALA A 216;TRP A 327;PHE A 330;PHE A 331;SER A 334;MET A 337;LEU A 348;PHE A 351;ASP A 352;THR A 355;TYR A 359","ERM A2001\r"],["4IB4_A_ERMA2001","4ib4","ERM","Ergotamine (DB00696)","Homo sapiens;escherichia coli","CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562","7tm_1;Cytochrom_B562",27,"TRP A 131;LEU A 132;ASP A 135;VAL A 136;SER A 139;THR A 140;CYS A 207;VAL A 208;LEU A 209;THR A 210;LYS A 211;PHE A 217;MET A 218;GLY A 221;SER A 222;ALA A 225;TRP A 337;PHE A 340;PHE A 341;ASN A 344;LEU A 347;VAL A 348;GLN A 359;LEU A 362;GLU A 363;VAL A 366;TYR A 370","ERM A2001\r"],["6BQG_A_ERMA1201","6bqg","ERM","Ergotamine (DB00696)","Homo sapiens;escherichia coli","5-HYDROXYTRYPTAMINE RECEPTOR 2C,SOLUBLE CYTOCHROME B562","7tm_1;Cytochrom_B562",24,"TRP A 130;ASP A 134;VAL A 135;SER A 138;THR A 139;CYS A 207;VAL A 208;LEU A 209;PHE A 214;VAL A 215;GLY A 218;SER A 219;ALA A 222;TRP A 324;PHE A 327;PHE A 328;ASN A 331;SER A 334;VAL A 335;GLU A 347;LEU A 350;ASN A 351;VAL A 354;TYR A 358","ERM A1201\r"]]