Results: Ligand

Ligand ID: TEP

Drugbank ID:
Theophylline
(DB00277)

Indication:
Theophylline is a xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.

LIST OF BINDING INTERFACES for query 'DB00277'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2A3A_A_TEPA1433	2a3a	TEP	Theophylline (DB00277)	Aspergillus fumigatus	CHITINASE	Glyco_hydro_18	11	TYR A 48 PHE A 76 GLY A 136 TRP A 137 ASP A 175 GLU A 177 MET A 243 TYR A 245 ASP A 246 TYR A 299 TRP A 384	TEP A1433
2A3A_A_TEPA1434	2a3a	TEP	Theophylline (DB00277)	Aspergillus fumigatus	CHITINASE	Glyco_hydro_18	4	TRP A 52 PHE A 76 THR A 138 TYR A 139	TEP A1434
2A3A_A_TEPA1435	2a3a	TEP	Theophylline (DB00277)	Aspergillus fumigatus	CHITINASE	Glyco_hydro_18	3	TRP A 137 GLU A 177 TYR A 178	TEP A1435
2A3A_A_TEPA1436	2a3a	TEP	Theophylline (DB00277)	Aspergillus fumigatus	CHITINASE	Glyco_hydro_18	4	ASP A 246 SER A 250 PHE A 251 ARG A 301	TEP A1436
3ROX_A_TEPA266	3rox	TEP	Theophylline (DB00277)	Mus musculus	APOLIPOPROTEIN A-I-BINDING PROTEIN	YjeF_N	13	ALA A 35 VAL A 38 ASP A 39 LEU A 42 PHE A 43 LEU A 53 ASP A 93 PHE A 160 ASP A 188 LEU A 211 THR A 212 ALA A 213 LYS A 215	TEP A 266
4EOH_A_TEPA402	4eoh	TEP	Theophylline (DB00277)	Homo sapiens	PYRIDOXAL KINASE	Phos_pyr_kin	9	SER A 12 VAL A 19 GLY A 20 HIS A 46 THR A 47 TYR A 84 VAL A 231 GLY A 232 ASP A 235	TEP A 402
5MZJ_A_TEPA2401	5mzj	TEP	Theophylline (DB00277)	Homo sapiens; escherichia coli	ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A	7tm_1 Cytochrom_B562	10	VAL A 84 LEU A 85 PHE A 168 GLU A 169 MET A 177 TRP A 246 LEU A 249 ASN A 253 MET A 270 ILE A 274	TEP A2401
6ICO_A_TEPA402	6ico	TEP	Theophylline (DB00277)	Pseudomonas putida	METHYLXANTHINE N1-DEMETHYLASE NDMA	Rieske VanA_C	11	PHE A 168 PHE A 174 LEU A 182 PRO A 219 PHE A 223 LEU A 235 LEU A 248 PHE A 281 ASN A 282 VAL A 285 PHE A 286	TEP A 402
6TUZ_A_TEPA531	6tuz	TEP	Theophylline (DB00277)	Homo sapiens	PALMITOLEOYL-PROTEIN CARBOXYLESTERASE NOTUM	PAE	11	TRP A 128 TYR A 129 VAL A 187 ALA A 233 THR A 236 PHE A 268 PRO A 287 ILE A 291 PHE A 319 PHE A 320 VAL A 346	TEP A 531
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2A3A_A_TEPA1433","2a3a","TEP","Theophylline (DB00277)","Aspergillus fumigatus","CHITINASE","Glyco_hydro_18",11,"TYR A  48;PHE A  76;GLY A 136;TRP A 137;ASP A 175;GLU A 177;MET A 243;TYR A 245;ASP A 246;TYR A 299;TRP A 384","TEP A1433\r"],["2A3A_A_TEPA1434","2a3a","TEP","Theophylline (DB00277)","Aspergillus fumigatus","CHITINASE","Glyco_hydro_18",4,"TRP A  52;PHE A  76;THR A 138;TYR A 139","TEP A1434\r"],["2A3A_A_TEPA1435","2a3a","TEP","Theophylline (DB00277)","Aspergillus fumigatus","CHITINASE","Glyco_hydro_18",3,"TRP A 137;GLU A 177;TYR A 178","TEP A1435\r"],["2A3A_A_TEPA1436","2a3a","TEP","Theophylline (DB00277)","Aspergillus fumigatus","CHITINASE","Glyco_hydro_18",4,"ASP A 246;SER A 250;PHE A 251;ARG A 301","TEP A1436\r"],["3ROX_A_TEPA266","3rox","TEP","Theophylline (DB00277)","Mus musculus","APOLIPOPROTEIN A-I-BINDING PROTEIN","YjeF_N",13,"ALA A  35;VAL A  38;ASP A  39;LEU A  42;PHE A  43;LEU A  53;ASP A  93;PHE A 160;ASP A 188;LEU A 211;THR A 212;ALA A 213;LYS A 215","TEP A 266\r"],["4EOH_A_TEPA402","4eoh","TEP","Theophylline (DB00277)","Homo sapiens","PYRIDOXAL KINASE","Phos_pyr_kin",9,"SER A  12;VAL A  19;GLY A  20;HIS A  46;THR A  47;TYR A  84;VAL A 231;GLY A 232;ASP A 235","TEP A 402\r"],["5MZJ_A_TEPA2401","5mzj","TEP","Theophylline (DB00277)","Homo sapiens;escherichia coli","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","7tm_1;Cytochrom_B562",10,"VAL A  84;LEU A  85;PHE A 168;GLU A 169;MET A 177;TRP A 246;LEU A 249;ASN A 253;MET A 270;ILE A 274","TEP A2401\r"],["6ICO_A_TEPA402","6ico","TEP","Theophylline (DB00277)","Pseudomonas putida","METHYLXANTHINE N1-DEMETHYLASE NDMA","Rieske;VanA_C",11,"PHE A 168;PHE A 174;LEU A 182;PRO A 219;PHE A 223;LEU A 235;LEU A 248;PHE A 281;ASN A 282;VAL A 285;PHE A 286","TEP A 402\r"],["6TUZ_A_TEPA531","6tuz","TEP","Theophylline (DB00277)","Homo sapiens","PALMITOLEOYL-PROTEIN CARBOXYLESTERASE NOTUM","PAE",11,"TRP A 128;TYR A 129;VAL A 187;ALA A 233;THR A 236;PHE A 268;PRO A 287;ILE A 291;PHE A 319;PHE A 320;VAL A 346","TEP A 531\r"]]