Ligand ID: QMR

Drugbank ID:
Varenicline
(DB01273)

Indication:
Varenicline is a partial agonist at nicotinic acetylcholine receptors used as an aid in smoking cessation.


LIST OF BINDING INTERFACES for query 'DB01273'
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DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
4AFG_A_QMRA12144afg QMRVarenicline
(DB01273) 		Capitella teleta CAPITELLA TELETA ACHBP Neur_chan_LBD 13PHE A 102
GLN B 116
ILE B 118
LEU B 126
ILE B 128
SER A 152
TRP A 153
VAL A 154
PHE B 175
TYR A 194
CYS A 196
CYS A 197
TYR A 201
QMR A1214
5AIN_A_QMRA12075ain QMRVarenicline
(DB01273) 		Aplysia californica SOLUBLE ACETYLCHOLINE RECEPTOR Neur_chan_LBD 14TYR B  53
ARG B  77
TYR A  91
ILE B 104
VAL B 106
MET B 114
ILE B 116
SER A 144
TRP A 145
VAL A 146
TYR A 186
CYS A 188
CYS A 189
TYR A 193
QMR A1207
6UR8_A_QMRA7026ur8 QMRVarenicline
(DB01273) 		Homo sapiens;
escherichia coli 		CHIMERA OF SOLUBLE CYTOCHROME B562 (BRIL) AND NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-4;
NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-2 		Neur_chan_LBD
Neur_chan_memb 		14TRP B  57
TYR A 100
SER B 108
ASN B 109
VAL B 111
PHE B 119
LEU B 121
SER A 155
TRP A 156
THR A 157
TYR A 197
CYS A 199
CYS A 200
TYR A 204
QMR A 702
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details