Ligand ID: P2E

Drugbank ID:
Dinoprostone
(DB00917)

Indication:
Dinoprostone is a prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease.

LIST OF BINDING INTERFACES for query 'DB00917'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3WFH_B_P2EB301	3wfh	P2E	Dinoprostone (DB00917)	Mus musculus	MAB FAB H FRAGMENT; MAB FAB L FRAGMENT	NA	20	HIS B  31 PHE A  33 HIS A  35 VAL A  37 TYR B  37 GLU B  39 TYR B  41 TRP A  47 TRP A  50 LEU B  94 GLY B  96 ALA A  97 HIS A  99 ALA A 100 TYR A 101 LEU B 101 ASP A 102 LYS A 103 PRO A 105 TRP A 107	P2E B 301		Details
6AK3_B_P2EB1201	6ak3	P2E	Dinoprostone (DB00917)	Homo sapiens; escherichia coli	PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE,SOLUBLE CYTOCHROME B562	7tm_1	24	PRO B  55 MET B  58 ASP B  99 GLY B 102 GLN B 103 THR B 106 THR B 107 VAL B 110 TYR B 114 MET B 137 GLY B 141 PRO B 204 THR B 206 TRP B 207 PHE B 209 TRP B 295 LEU B 298 LEU B 329 VAL B 332 ARG B 333 ALA B 335 SER B 336 GLN B 339 ILE B 340	P2E B1201		Details
7CX2_R_P2ER401	7cx2	P2E	Dinoprostone (DB00917)	Homo sapiens; synthetic construct	PROSTAGLANDIN E2 RECEPTOR EP2 SUBTYPE	7tm_1	23	GLU R  23 SER R  28 MET R  31 PHE R  32 GLY R  81 THR R  82 ILE R  85 SER R  86 VAL R  89 TYR R  93 MET R 116 SER R 120 THR R 123 MET R 124 THR R 185 TRP R 186 LEU R 298 LEU R 301 ARG R 302 LEU R 304 SER R 305 ASN R 307 SER R 308	P2E R 401		Details
7D7M_A_P2EA401	7d7m	P2E	Dinoprostone (DB00917)	Homo sapiens; lama glama	PROSTAGLANDIN E2 RECEPTOR EP4 SUBTYPE	7tm_1	22	PRO A  24 MET A  27 PHE A  28 GLY A  68 THR A  69 VAL A  72 SER A  73 THR A  76 TYR A  80 LEU A  99 SER A 103 PRO A 166 THR A 168 TRP A 169 LEU A 288 LEU A 312 ILE A 315 ARG A 316 ALA A 318 SER A 319 PRO A 322 ILE A 323	P2E A 401		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3WFH_B_P2EB301","3wfh","P2E","Dinoprostone (DB00917)","Mus musculus","MAB FAB H FRAGMENT;MAB FAB L FRAGMENT","NA",20,"HIS B 31;PHE A 33;HIS A 35;VAL A 37;TYR B 37;GLU B 39;TYR B 41;TRP A 47;TRP A 50;LEU B 94;GLY B 96;ALA A 97;HIS A 99;ALA A 100;TYR A 101;LEU B 101;ASP A 102;LYS A 103;PRO A 105;TRP A 107","P2E B 301\r"],["6AK3_B_P2EB1201","6ak3","P2E","Dinoprostone (DB00917)","Homo sapiens;escherichia coli","PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE,SOLUBLE CYTOCHROME B562","7tm_1",24,"PRO B 55;MET B 58;ASP B 99;GLY B 102;GLN B 103;THR B 106;THR B 107;VAL B 110;TYR B 114;MET B 137;GLY B 141;PRO B 204;THR B 206;TRP B 207;PHE B 209;TRP B 295;LEU B 298;LEU B 329;VAL B 332;ARG B 333;ALA B 335;SER B 336;GLN B 339;ILE B 340","P2E B1201\r"],["7CX2_R_P2ER401","7cx2","P2E","Dinoprostone (DB00917)","Homo sapiens;synthetic construct","PROSTAGLANDIN E2 RECEPTOR EP2 SUBTYPE","7tm_1",23,"GLU R 23;SER R 28;MET R 31;PHE R 32;GLY R 81;THR R 82;ILE R 85;SER R 86;VAL R 89;TYR R 93;MET R 116;SER R 120;THR R 123;MET R 124;THR R 185;TRP R 186;LEU R 298;LEU R 301;ARG R 302;LEU R 304;SER R 305;ASN R 307;SER R 308","P2E R 401\r"],["7D7M_A_P2EA401","7d7m","P2E","Dinoprostone (DB00917)","Homo sapiens;lama glama","PROSTAGLANDIN E2 RECEPTOR EP4 SUBTYPE","7tm_1",22,"PRO A 24;MET A 27;PHE A 28;GLY A 68;THR A 69;VAL A 72;SER A 73;THR A 76;TYR A 80;LEU A 99;SER A 103;PRO A 166;THR A 168;TRP A 169;LEU A 288;LEU A 312;ILE A 315;ARG A 316;ALA A 318;SER A 319;PRO A 322;ILE A 323","P2E A 401\r"]]