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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 4laj | ACA | Aminocaproic acid (DB00513) | Aminocaproic acid is an antifibrinolytic agent used to induce clotting postoperatively. | HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN (Human immunodeficiency virus 1;lama glama;synthetic construct) | NA | ||
| 4ldo | ALE | Epinephrine (DB00668) | Epinephrine is a hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. | LYSOZYME, BETA-2 ADRENERGIC RECEPTOR (Enterobacteria phage t4;homo sapiens;lama glama) | 7tm_1Phage_lysozyme | ||
| 5vl2 | 9EG | Triclocarban (DB11155) | Triclocarban is an antibacterial agent used in liquid soaps and body washes. | T4 NANOBODY (Lama glama) | NA | ||
| 5vm0 | 9EG | Triclocarban (DB11155) | Triclocarban is an antibacterial agent used in liquid soaps and body washes. | CAMELID NANOBODY VHH T9 (Lama glama) | NA | ||
| 5vm6 | 9EG | Triclocarban (DB11155) | Triclocarban is an antibacterial agent used in liquid soaps and body washes. | SINGLE DOMAIN CAMELID NANOBODY VHH T10 (Lama glama) | NA | ||
| 5y80 | IRE | Gefitinib (DB00317) | Gefitinib is a tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria. | CYCLIN-G-ASSOCIATED KINASE (Homo sapiens;lama glama) | Pkinase | ||
| 6a96 | ABU | Gamma-aminobutyric acid (DB02530) | The most common inhibitory neurotransmitter in the central nervous system. | GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-5,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-5;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3 (Lama glama;homo sapiens) | Neur_chan_LBDNeur_chan_memb | ||
| 6gs4 | F9E | Valganciclovir (DB01610) | Valganciclovir is an antiviral medication used to treat cytomegalovirus (CMV) retinitis in patients diagnosed with acquired immunodeficiency syndrome (AIDS). | DIPEPTIDE AND TRIPEPTIDE PERMEASE A (Escherichia coli k-12;lama glama) | PTR2 | ||
| 6h7j | 5FW | Isoprenaline (DB01064) | Isoprenaline is a catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block. | BETA-1 ADRENERGIC RECEPTOR (Escherichia coli (strain k12);meleagris gallopavo;lama glama) | 7tm_1 | ||
| 6h7l | Y00 | Dobutamine (DB00841) | Dobutamine is a beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. | BETA-1 ADRENERGIC RECEPTOR (Escherichia coli (strain k12);meleagris gallopavo;lama glama) | 7tm_1 | ||
| 6h7m | 68H | Levosalbutamol (DB13139) | Levosalbutamol is a beta-2 adrenergic receptor agonist used to treat COPD and asthma. | BETA-1 ADRENERGIC RECEPTOR (Escherichia coli (strain k12);meleagris gallopavo;lama glama) | 7tm_1 | ||
| 6h7n | FVK | Xamoterol (DB13781) | Xamoterol is a β1-adrenoceptor partial agonist that has shown to improve systolic and diastolic function in studies with heart failure patients. It modulates the sympathetic control of the heart but... | BETA-1 ADRENERGIC RECEPTOR (Escherichia coli (strain k12);meleagris gallopavo;lama glama) | 7tm_1 | ||
| 6huj | ABU | Gamma-aminobutyric acid (DB02530) | The most common inhibitory neurotransmitter in the central nervous system. | GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3 (Bos taurus;homo sapiens;lama glama) | Neur_chan_LBDNeur_chan_memb | ||
| 6huo | 08H | Alprazolam (DB00404) | Alprazolam is a triazolobenzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression. | GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2 (Bos taurus;homo sapiens;lama glama) | Neur_chan_LBDNeur_chan_memb | ||
| 6huo | ABU | Gamma-aminobutyric acid (DB02530) | The most common inhibitory neurotransmitter in the central nervous system. | GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3 (Bos taurus;homo sapiens;lama glama) | Neur_chan_LBDNeur_chan_memb | ||
| 6hup | DZP | Diazepam (DB00829) | Diazepam is a long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures. | GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3 (Bos taurus;homo sapiens;lama glama) | Neur_chan_LBDNeur_chan_memb | ||
| 6hup | DZP | Diazepam (DB00829) | Diazepam is a long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures. | GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2 (Bos taurus;homo sapiens;lama glama) | Neur_chan_LBDNeur_chan_memb | ||
| 6ibl | H98 | Arformoterol (DB01274) | Arformoterol is a beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. | THIOREDOXIN 1,BETA-1 ADRENERGIC RECEPTOR (Escherichia coli (strain k12);meleagris gallopavo;lama glama) | 7tm_1Thioredoxin | ||
| 6mxt | K5Y | Salmeterol (DB00938) | Salmeterol is a long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD. | ENDOLYSIN, BETA-2 ADRENERGIC RECEPTOR CHIMERA (Enterobacteria phage t4;homo sapiens;lama glama) | 7tm_1Phage_lysozyme | ||
| 6rum | TOP | Trimethoprim (DB00440) | Trimethoprim is an antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract. | GFP-LAMA-G97 A GFP ENHANCER NANOBODY WITH CPDHFR INSERTION (Lama glama;escherichia coli (strain k12)) | NA | ||
| 6ssi | ABU | Gamma-aminobutyric acid (DB02530) | The most common inhibitory neurotransmitter in the central nervous system. | CYS-LOOP LIGAND-GATED ION CHANNEL (Dickeya chrysanthemi;lama glama) | NA | ||
| 7a5v | HSM | Histamine (DB05381) | Histamine is an ingredient of topical drugs for the relief of joint pain or muscle aches and pains. | GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3 (Homo sapiens;lama glama) | Neur_chan_LBDNeur_chan_memb | ||
| 7bz2 | H98 | Arformoterol (DB01274) | Arformoterol is a beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. | BETA2 ADRENERGIC RECEPTOR (Homo sapiens;bos taurus;lama glama) | 7tm_1 | ||
| 7ckw | G3C | Fenoldopam (DB00800) | Fenoldopam is a dopamine D1 receptor agonist used for the short term management of hypertension. | D(1A) DOPAMINE RECEPTOR (Homo sapiens;lama glama) | 7tm_1 | ||
| 7ckz | LDP | Dopamine (DB00988) | Dopamine is a catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension. | D(1A) DOPAMINE RECEPTOR (Homo sapiens;lama glama) | 7tm_1 | ||
| 7d7m | P2E | Dinoprostone (DB00917) | Dinoprostone is a prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease. | PROSTAGLANDIN E2 RECEPTOR EP4 SUBTYPE (Homo sapiens;lama glama) | 7tm_1 | ||
| 7dhi | 68H | Levosalbutamol (DB13139) | Levosalbutamol is a beta-2 adrenergic receptor agonist used to treat COPD and asthma. | BETA-2 ADRENERGIC RECEPTOR (Homo sapiens;bos taurus;lama glama) | 7tm_1 | ||
| 7dhr | 5FW | Isoprenaline (DB01064) | Isoprenaline is a catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block. | BETA-2 ADRENERGIC RECEPTOR (Homo sapiens;bos taurus;lama glama) | 7tm_1 | ||
| 7jjo | 5FW | Isoprenaline (DB01064) | Isoprenaline is a catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block. | BETA1-ADRENERGIC RECEPTOR (Bos taurus;lama glama;meleagris gallopavo) | 7tm_1 | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |