Results: Ligand

Ligand ID: DZP

Drugbank ID:
Diazepam
(DB00829)

Indication:
Diazepam is a long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures.

LIST OF BINDING INTERFACES for query 'DB00829'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2BXF_A_DZPA2001	2bxf	DZP	Diazepam (DB00829)	Homo sapiens	SERUM ALBUMIN	Serum_albumin	16	PRO A 384 LEU A 387 ILE A 388 ASN A 391 CYS A 392 PHE A 403 LEU A 407 TYR A 411 LEU A 430 VAL A 433 GLY A 434 CYS A 438 ALA A 449 GLU A 450 LEU A 453 ARG A 485	DZP A2001
6HUP_B_DZPB502	6hup	DZP	Diazepam (DB00829)	Bos taurus; homo sapiens; lama glama	GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1; GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3	Neur_chan_LBD Neur_chan_memb	13	ILE A 228 LEU A 232 PRO A 233 MET A 236 THR A 237 MET B 261 THR B 262 THR A 265 ASN B 265 LEU A 269 LEU B 285 MET B 286 PHE B 289	DZP B 502
6HUP_D_DZPD2001	6hup	DZP	Diazepam (DB00829)	Bos taurus; homo sapiens; lama glama	GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1; GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2	Neur_chan_LBD Neur_chan_memb	12	TYR C 58 ASN C 60 PHE C 77 PHE D 100 HIS D 102 SER D 159 TYR D 160 VAL D 203 GLN D 204 SER D 205 SER D 206 TYR D 210	DZP D2001
6X3X_A_DZPA406	6x3x	DZP	Diazepam (DB00829)	Homo sapiens; mus musculus	GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1; GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-2	Neur_chan_LBD Neur_chan_memb	13	ILE B 228 LEU B 232 PRO B 233 MET B 236 THR B 237 MET A 261 THR A 262 ASN A 265 THR B 265 LEU B 269 LEU A 285 MET A 286 PHE A 289	DZP A 406
6X3X_D_DZPD404	6x3x	DZP	Diazepam (DB00829)	Homo sapiens; mus musculus	GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1; GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2	Neur_chan_LBD	12	TYR E 58 ASN E 60 PHE E 77 PHE D 100 HIS D 102 SER D 159 TYR D 160 VAL D 203 GLN D 204 SER D 205 SER D 206 TYR D 210	DZP D 404
6X3X_E_DZPE403	6x3x	DZP	Diazepam (DB00829)	Homo sapiens; mus musculus	GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-2; GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2	Neur_chan_LBD Neur_chan_memb	14	LEU A 223 GLN A 224 MET A 227 PRO A 228 LEU A 231 ILE A 264 MET E 276 THR E 277 SER E 280 THR E 281 ARG E 284 ASP E 297 SER E 301 PHE E 304	DZP E 403
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2BXF_A_DZPA2001","2bxf","DZP","Diazepam (DB00829)","Homo sapiens","SERUM ALBUMIN","Serum_albumin",16,"PRO A 384;LEU A 387;ILE A 388;ASN A 391;CYS A 392;PHE A 403;LEU A 407;TYR A 411;LEU A 430;VAL A 433;GLY A 434;CYS A 438;ALA A 449;GLU A 450;LEU A 453;ARG A 485","DZP A2001\r"],["6HUP_B_DZPB502","6hup","DZP","Diazepam (DB00829)","Bos taurus;homo sapiens;lama glama","GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-3","Neur_chan_LBD;Neur_chan_memb",13,"ILE A 228;LEU A 232;PRO A 233;MET A 236;THR A 237;MET B 261;THR B 262;THR A 265;ASN B 265;LEU A 269;LEU B 285;MET B 286;PHE B 289","DZP B 502\r"],["6HUP_D_DZPD2001","6hup","DZP","Diazepam (DB00829)","Bos taurus;homo sapiens;lama glama","GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2","Neur_chan_LBD;Neur_chan_memb",12,"TYR C  58;ASN C  60;PHE C  77;PHE D 100;HIS D 102;SER D 159;TYR D 160;VAL D 203;GLN D 204;SER D 205;SER D 206;TYR D 210","DZP D2001\r"],["6X3X_A_DZPA406","6x3x","DZP","Diazepam (DB00829)","Homo sapiens;mus musculus","GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-2","Neur_chan_LBD;Neur_chan_memb",13,"ILE B 228;LEU B 232;PRO B 233;MET B 236;THR B 237;MET A 261;THR A 262;ASN A 265;THR B 265;LEU B 269;LEU A 285;MET A 286;PHE A 289","DZP A 406\r"],["6X3X_D_DZPD404","6x3x","DZP","Diazepam (DB00829)","Homo sapiens;mus musculus","GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2","Neur_chan_LBD",12,"TYR E  58;ASN E  60;PHE E  77;PHE D 100;HIS D 102;SER D 159;TYR D 160;VAL D 203;GLN D 204;SER D 205;SER D 206;TYR D 210","DZP D 404\r"],["6X3X_E_DZPE403","6x3x","DZP","Diazepam (DB00829)","Homo sapiens;mus musculus","GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-2;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2","Neur_chan_LBD;Neur_chan_memb",14,"LEU A 223;GLN A 224;MET A 227;PRO A 228;LEU A 231;ILE A 264;MET E 276;THR E 277;SER E 280;THR E 281;ARG E 284;ASP E 297;SER E 301;PHE E 304","DZP E 403\r"]]