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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 1ewj | BLM | Bleomycin (DB00290) | Bleomycin is a chemotherapy agent used to treat various malignancies, including head and neck malignancy, lymphoma, and testicular tumors, among others. | BLEOMYCIN RESISTANCE DETERMINANT (Klebsiella pneumoniae) | NA | ||
| 1nd4 | KAN | Kanamycin (DB01172) | Kanamycin is an aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria. | AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE (Klebsiella pneumoniae) | APH | ||
| 1vm1 | TAZ | Tazobactam (DB01606) | Tazobactam is a beta lactamase inhibitor administered with antibiotics such as piperacillin and ceftolozane to prevent their degradation, resulting in increased efficacy. | BETA-LACTAMASE SHV-1 (Klebsiella pneumoniae) | Beta-lactamase2 | ||
| 3o7j | 2AL | Allantoin (DB11100) | Allantoin is an ingredient used in skin care products to relieve irritation and protect minor cuts, scrapes, and burns. | OHCU DECARBOXYLASE (Klebsiella pneumoniae subsp. pneumoniae) | OHCU_decarbox | ||
| 3qvk | 2AL | Allantoin (DB11100) | Allantoin is an ingredient used in skin care products to relieve irritation and protect minor cuts, scrapes, and burns. | PUTATIVE HYDANTOIN RACEMASE (Klebsiella pneumoniae subsp. pneumoniae) | Asp_Glu_race | ||
| 4ey2 | 0RM | Meticillin (DB01603) | One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection. | BETA-LACTAMASE NDM-1 (Klebsiella pneumoniae) | Lactamase_B | ||
| 4eyb | 0WO | Oxacillin (DB00713) | Oxacillin is a penicillin antibiotic used to treat a number of susceptible bacterial infections. | BETA-LACTAMASE NDM-1 (Klebsiella pneumoniae) | Lactamase_B | ||
| 4eyl | 0RV | Meropenem (DB00760) | Meropenem is a carbapenem antibiotic used to treat a wide variety of infections in the body. | BETA-LACTAMASE NDM-1 (Klebsiella pneumoniae) | Lactamase_B | ||
| 4fh2 | 0RN | Sulbactam (DB09324) | Sulbactam is an beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections. | BETA-LACTAMASE SHV-1 (Klebsiella pneumoniae) | Beta-lactamase2 | ||
| 4pm5 | CE3 | Cefotaxime (DB00493) | Cefotaxime is a third generation cephalosporin used to treat susceptible Gram negative and Gram positive bacterial infections. | BETA-LACTAMASE CTX-M-14 (Klebsiella pneumoniae subsp. pneumoniae) | Beta-lactamase2 | ||
| 4r88 | 1LD | Flucytosine (DB01099) | Flucytosine is an antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus. | CYTOSINE DEAMINASE (Klebsiella pneumoniae) | Amidohydro_3 | ||
| 4wbg | AZR | Aztreonam (DB00355) | Aztreonam is a beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria. | BETA-LACTAMASE (Klebsiella pneumoniae) | Beta-lactamase | ||
| 4wql | KAN | Kanamycin (DB01172) | Kanamycin is an aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria. | 2''-AMINOGLYCOSIDE NUCLEOTIDYLTRANSFERASE (Klebsiella pneumoniae) | Aminoglyc_resit | ||
| 4xuz | 4D6 | Vaborbactam (DB12107) | Vaborbactam is a beta lactamase inhibitor used to treat complicated urinary tract infections. | BETA-LACTAMASE (Klebsiella pneumoniae subsp. pneumoniae) | Beta-lactamase2 | ||
| 5a5z | WJZ | Tiopronin (DB06823) | Tiopronin is a thiol agent indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria. | BETA-LACTAMASE NDM-1 (Klebsiella pneumoniae) | Lactamase_B | ||
| 5v3d | FCN | Fosfomycin (DB00828) | Fosfomycin is a broad spectrum antibiotic used to treat uncomplicated urinary tract infections. | FOSFOMYCIN RESISTANCE PROTEIN (Klebsiella pneumoniae) | Glyoxalase | ||
| 5zio | X8Z | Captopril (DB01197) | Captopril is an ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy. | METALLO-BETA-LACTAMASE TYPE 2 (Klebsiella pneumoniae) | Lactamase_B | ||
| 5zj8 | 9DC | Dimercaprol (DB06782) | Dimercaprol is a chelating agent used as an antidote to arsenic, gold, and mercury poisoning, as well as acute lead poisoning in combination with edetate calcium disodium. | METALLO-BETA-LACTAMASE TYPE 2 (Klebsiella pneumoniae) | Lactamase_B | ||
| 6p99 | 1RG | Ertapenem (DB00303) | Ertapenem is a carbapenem antibiotic used for the treatment of moderate to severe bacterial infections caused by specific sensitive organisms. | BETA-LACTAMASE (Klebsiella pneumoniae) | Transpeptidase | ||
| 6p9c | O6P | Doripenem (DB06211) | Doripenem is an antibiotic of the penem class used to treat complicated intra-abdominal and urinary tract infections. | BETA-LACTAMASE (Klebsiella pneumoniae) | Transpeptidase | ||
| 6td0 | 4D6 | Vaborbactam (DB12107) | Vaborbactam is a beta lactamase inhibitor used to treat complicated urinary tract infections. | CARBAPENEM-HYDROLYZING BETA-LACTAMASE KPC (Klebsiella pneumoniae) | Beta-lactamase2 | ||
| 7lnl | 8YF | Imipenem (DB01598) | Imipenem is a carbapenem antibiotic normally administered with cilastatin to treat a variety of infections. | CARBAPENEM-HYDROLYZING BETA-LACTAMASE KPC (Klebsiella pneumoniae) | Beta-lactamase2 | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |