Results: Ligand

Ligand ID: BLM

Drugbank ID:
Bleomycin
(DB00290)

Indication:
Bleomycin is a chemotherapy agent used to treat various malignancies, including head and neck malignancy, lymphoma, and testicular tumors, among others.

LIST OF BINDING INTERFACES for query 'DB00290'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1EWJ_A_BLMA1001	1ewj	BLM	Bleomycin (DB00290)	Klebsiella pneumoniae	BLEOMYCIN RESISTANCE DETERMINANT	NA	31	PHE B 30 GLY B 34 TRP B 35 ILE B 37 MET B 44 GLU B 46 PHE B 48 PRO A 55 LEU A 56 ALA A 57 SER A 58 TRP A 59 PHE A 60 SER A 61 ARG A 65 SER A 85 SER A 86 GLY A 87 ARG A 90 GLN A 97 TRP A 99 MET A 103 ALA A 105 VAL A 107 GLY A 111 THR A 112 LEU A 113 ARG A 115 ILE A 117 ASN A 119 GLU A 120	BLM A1001
1JIF_B_BLMB401	1jif	BLM	Bleomycin (DB00290)	Streptomyces verticillus	BLEOMYCIN-BINDING PROTEIN	NA	26	ASP A 32 PHE A 33 PHE A 38 ARG A 42 HIS A 49 SER A 51 ARG A 52 THR A 53 ALA B 259 ASP B 260 ASN B 261 THR B 262 TRP B 265 TYR B 286 ALA B 287 THR B 289 THR B 295 PRO B 301 ALA B 302 GLU B 305 ALA B 307 ARG B 309 GLY B 313 ASN B 314 CYS B 315 HIS B 317	BLM B 401
1JIF_B_BLMB402	1jif	BLM	Bleomycin (DB00290)	Streptomyces verticillus	BLEOMYCIN-BINDING PROTEIN	NA	26	ALA A 59 ASP A 60 ASN A 61 THR A 62 TRP A 65 GLU A 67 TYR A 86 ALA A 87 THR A 89 THR A 95 PRO A 101 ALA A 102 ALA A 107 ARG A 109 GLY A 113 ASN A 114 CYS A 115 HIS A 117 ASP B 232 PHE B 233 PHE B 238 ARG B 247 HIS B 249 SER B 251 ARG B 252 THR B 253	BLM B 402
1XRK_A_BLMA402	1xrk	BLM	Bleomycin (DB00290)	Streptoalloteichus hindustanus	BLEOMYCIN RESISTANCE PROTEIN	Glyoxalase_7	24	VAL B 32 PHE B 33 GLU B 35 PHE B 38 PHE B 49 SER B 51 ALA B 52 VAL B 53 PRO A 59 ASP A 60 ASN A 61 THR A 62 GLN A 63 TRP A 65 PHE A 86 ARG A 87 THR A 95 TRP A 102 ALA A 107 ARG A 109 GLY A 113 ASN A 114 CYS A 115 HIS A 117	BLM A 402
2A4X_A_BLMA700	2a4x	BLM	Bleomycin (DB00290)	Streptomyces caespitosus	MITOMYCIN-BINDING PROTEIN	Glyoxalase	17	HIS A 71 ALA A 74 GLU A 78 TRP A 108 GLN A 110 TYR A 112 ILE A 114 VAL A 122 ASP A 124 PHE A 126 SER B 206 HIS B 238 GLU B 240 ARG B 248 ASP B 252 THR B 256 TYR B 260	BLM A 700
2ZW7_A_BLMA402	2zw7	BLM	Bleomycin (DB00290)	Streptomyces verticillus	BLEOMYCIN ACETYLTRANSFERASE	Acetyltransf_1 Glyoxalase_6	27	TRP A 43 TRP A 44 THR A 45 LEU A 87 GLY A 88 THR A 90 VAL A 92 GLY A 94 LEU A 95 THR A 96 GLU A 130 TRP A 132 LEU A 155 ALA A 156 GLN A 157 HIS A 158 TYR A 159 PRO A 160 GLU B 188 PHE B 211 GLU B 218 PHE B 219 SER B 228 ARG B 234 ALA B 236 TRP A 280 GLY A 281	BLM A 402
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1EWJ_A_BLMA1001","1ewj","BLM","Bleomycin (DB00290)","Klebsiella pneumoniae","BLEOMYCIN RESISTANCE DETERMINANT","NA",31,"PHE B  30;GLY B  34;TRP B  35;ILE B  37;MET B  44;GLU B  46;PHE B  48;PRO A  55;LEU A  56;ALA A  57;SER A  58;TRP A  59;PHE A  60;SER A  61;ARG A  65;SER A  85;SER A  86;GLY A  87;ARG A  90;GLN A  97;TRP A  99;MET A 103;ALA A 105;VAL A 107;GLY A 111;THR A 112;LEU A 113;ARG A 115;ILE A 117;ASN A 119;GLU A 120","BLM A1001\r"],["1JIF_B_BLMB401","1jif","BLM","Bleomycin (DB00290)","Streptomyces verticillus","BLEOMYCIN-BINDING PROTEIN","NA",26,"ASP A  32;PHE A  33;PHE A  38;ARG A  42;HIS A  49;SER A  51;ARG A  52;THR A  53;ALA B 259;ASP B 260;ASN B 261;THR B 262;TRP B 265;TYR B 286;ALA B 287;THR B 289;THR B 295;PRO B 301;ALA B 302;GLU B 305;ALA B 307;ARG B 309;GLY B 313;ASN B 314;CYS B 315;HIS B 317","BLM B 401\r"],["1JIF_B_BLMB402","1jif","BLM","Bleomycin (DB00290)","Streptomyces verticillus","BLEOMYCIN-BINDING PROTEIN","NA",26,"ALA A  59;ASP A  60;ASN A  61;THR A  62;TRP A  65;GLU A  67;TYR A  86;ALA A  87;THR A  89;THR A  95;PRO A 101;ALA A 102;ALA A 107;ARG A 109;GLY A 113;ASN A 114;CYS A 115;HIS A 117;ASP B 232;PHE B 233;PHE B 238;ARG B 247;HIS B 249;SER B 251;ARG B 252;THR B 253","BLM B 402\r"],["1XRK_A_BLMA402","1xrk","BLM","Bleomycin (DB00290)","Streptoalloteichus hindustanus","BLEOMYCIN RESISTANCE PROTEIN","Glyoxalase_7",24,"VAL B  32;PHE B  33;GLU B  35;PHE B  38;PHE B  49;SER B  51;ALA B  52;VAL B  53;PRO A  59;ASP A  60;ASN A  61;THR A  62;GLN A  63;TRP A  65;PHE A  86;ARG A  87;THR A  95;TRP A 102;ALA A 107;ARG A 109;GLY A 113;ASN A 114;CYS A 115;HIS A 117","BLM A 402\r"],["2A4X_A_BLMA700","2a4x","BLM","Bleomycin (DB00290)","Streptomyces caespitosus","MITOMYCIN-BINDING PROTEIN","Glyoxalase",17,"HIS A  71;ALA A  74;GLU A  78;TRP A 108;GLN A 110;TYR A 112;ILE A 114;VAL A 122;ASP A 124;PHE A 126;SER B 206;HIS B 238;GLU B 240;ARG B 248;ASP B 252;THR B 256;TYR B 260","BLM A 700\r"],["2ZW7_A_BLMA402","2zw7","BLM","Bleomycin (DB00290)","Streptomyces verticillus","BLEOMYCIN ACETYLTRANSFERASE","Acetyltransf_1;Glyoxalase_6",27,"TRP A  43;TRP A  44;THR A  45;LEU A  87;GLY A  88;THR A  90;VAL A  92;GLY A  94;LEU A  95;THR A  96;GLU A 130;TRP A 132;LEU A 155;ALA A 156;GLN A 157;HIS A 158;TYR A 159;PRO A 160;GLU B 188;PHE B 211;GLU B 218;PHE B 219;SER B 228;ARG B 234;ALA B 236;TRP A 280;GLY A 281","BLM A 402\r"]]