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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 2vv0 | HXA | Doconexent (DB03756) | Doconexent is an omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health. | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens) | Hormone_recep | ||
| 3adx | IMN | Indomethacin (DB00328) | Indomethacin is a nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens) | Hormone_recep | ||
| 3qt0 | 486 | Mifepristone (DB00834) | Mifepristone is a cortisol receptor blocker used to treat Cushing's syndrome, and to terminate pregnancies up to 70 days gestation. | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens) | Hormone_recep | ||
| 3vn2 | TLS | Telmisartan (DB00966) | Telmisartan is an ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure. | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens;synthetic construct) | Hormone_recep | ||
| 4oj4 | DIF | Diclofenac (DB00586) | Diclofenac is an NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens) | Hormone_recep | ||
| 5y2o | 8N6 | Pioglitazone (DB01132) | Pioglitazone is a thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus. | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens) | Hormone_recep | ||
| 6dgo | GD4 | Troglitazone (DB00197) | Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by pioglitazone and rosiglitazone. | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens) | Hormone_recep | ||
| 6ktn | STI | Imatinib (DB00619) | Imatinib is a tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens;synthetic construct) | Hormone_recep | ||
| 7awc | BRL | Rosiglitazone (DB00412) | Rosiglitazone is a thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes. | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens) | Hormone_recep | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |