Results: Ligand

Ligand ID: HXA

Drugbank ID:
Doconexent
(DB03756)

Indication:
Doconexent is an omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health.

LIST OF BINDING INTERFACES for query 'DB03756'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1FDQ_A_HXAA133	1fdq	HXA	Doconexent (DB03756)	Homo sapiens	FATTY ACID-BINDING PROTEIN, BRAIN	Lipocalin	23	PHE A 16 MET A 20 LEU A 23 THR A 29 GLY A 33 PRO A 38 VAL A 40 THR A 53 THR A 60 ILE A 62 GLU A 72 THR A 73 THR A 74 ALA A 75 ASP A 76 ARG A 78 GLN A 95 PHE A 104 ARG A 106 MET A 115 LEU A 117 ARG A 126 TYR A 128	HXA A 133
1MV9_A_HXAA200	1mv9	HXA	Doconexent (DB03756)	Homo sapiens; synthetic construct	RXR RETINOID X RECEPTOR	Hormone_recep	21	VAL A 265 ILE A 268 ALA A 271 ALA A 272 GLN A 275 TRP A 305 ASN A 306 LEU A 309 ILE A 310 PHE A 313 ARG A 316 ILE A 324 LEU A 326 ALA A 327 VAL A 342 ILE A 345 PHE A 346 CYS A 432 HIS A 435 LEU A 436 PHE A 439	HXA A 200
2BYO_A_HXAA1215	2byo	HXA	Doconexent (DB03756)	Mycobacterium tuberculosis	LIPOPROTEIN LPPX	LppX_LprAFG	23	ILE A 28 LEU A 32 THR A 35 LYS A 36 VAL A 41 VAL A 43 VAL A 64 GLY A 120 VAL A 121 GLN A 123 LEU A 125 VAL A 128 ILE A 147 THR A 148 GLY A 149 ILE A 151 ALA A 169 THR A 170 VAL A 171 LEU A 181 ALA A 184 LEU A 195 GLN A 197	HXA A1215
2G7Z_A_HXAA9136	2g7z	HXA	Doconexent (DB03756)	Streptococcus pyogenes	CONSERVED HYPOTHETICAL PROTEIN SPY1493	DegV	27	LEU A 29 THR A 62 SER A 63 GLN A 64 LEU A 90 LEU A 94 SER A 95 GLY A 96 THR A 97 THR A 120 ASP A 121 LEU A 157 ILE A 159 ARG A 172 LEU A 192 LEU A 197 SER A 231 TYR A 232 ALA A 233 THR A 259 ILE A 262 ILE A 263 HIS A 266 THR A 267 ALA A 271 PHE A 272 ALA A 273	HXA A9136
2VV0_A_HXAA1476	2vv0	HXA	Doconexent (DB03756)	Homo sapiens	PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA	Hormone_recep	19	ILE A 281 GLY A 284 CYS A 285 ARG A 288 SER A 289 HIS A 323 ILE A 326 TYR A 327 LEU A 330 VAL A 339 LEU A 340 ILE A 341 SER A 342 MET A 348 MET A 364 HIS A 449 LEU A 453 LEU A 469 TYR A 473	HXA A1476
3HS7_A_HXAA1	3hs7	HXA	Doconexent (DB03756)	Mus musculus	PROSTAGLANDIN G/H SYNTHASE 2	An_peroxidase EGF	27	VAL A 116 ARG A 120 PHE A 205 PHE A 209 GLY A 227 VAL A 228 TYR A 348 VAL A 349 LEU A 352 SER A 353 TYR A 355 ASN A 375 ILE A 377 PHE A 381 LEU A 384 TYR A 385 TRP A 387 PHE A 518 MET A 522 VAL A 523 GLY A 526 ALA A 527 PHE A 529 SER A 530 LEU A 531 GLY A 533 LEU A 534	HXA A 1
5J0Z_A_HXAA408	5j0z	HXA	Doconexent (DB03756)	Gloeobacter violaceus (strain pcc 7421)	PROTON-GATED ION CHANNEL	NA	4	ARG A 117 ARG A 118 PHE E 195 MET A 252	HXA A 408
5Y5C_B_HXAB201	5y5c	HXA	Doconexent (DB03756)	Bos taurus	BETA-LACTOGLOBULIN	Lipocalin	21	PRO B 38 PRO A 38 VAL A 41 LEU A 46 LEU A 54 ILE A 56 LEU A 58 LYS B 60 GLU B 62 LYS B 69 LYS A 69 ILE A 71 ILE A 84 ASP A 85 LEU B 87 VAL A 92 VAL A 94 LEU A 103 PHE A 105 MET A 107 LEU A 122	HXA B 201
5Y5C_B_HXAB202	5y5c	HXA	Doconexent (DB03756)	Bos taurus	BETA-LACTOGLOBULIN	Lipocalin	19	VAL B 41 VAL B 43 LEU B 46 ILE B 56 LEU B 58 ILE B 71 ILE B 84 ASP B 85 ALA A 86 LEU B 87 GLU A 89 ASN B 90 VAL B 92 LEU B 103 PHE B 105 MET B 107 ASN B 109 SER B 116 LEU B 122	HXA B 202
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1FDQ_A_HXAA133","1fdq","HXA","Doconexent (DB03756)","Homo sapiens","FATTY ACID-BINDING PROTEIN, BRAIN","Lipocalin",23,"PHE A  16;MET A  20;LEU A  23;THR A  29;GLY A  33;PRO A  38;VAL A  40;THR A  53;THR A  60;ILE A  62;GLU A  72;THR A  73;THR A  74;ALA A  75;ASP A  76;ARG A  78;GLN A  95;PHE A 104;ARG A 106;MET A 115;LEU A 117;ARG A 126;TYR A 128","HXA A 133\r"],["1MV9_A_HXAA200","1mv9","HXA","Doconexent (DB03756)","Homo sapiens;synthetic construct","RXR RETINOID X RECEPTOR","Hormone_recep",21,"VAL A 265;ILE A 268;ALA A 271;ALA A 272;GLN A 275;TRP A 305;ASN A 306;LEU A 309;ILE A 310;PHE A 313;ARG A 316;ILE A 324;LEU A 326;ALA A 327;VAL A 342;ILE A 345;PHE A 346;CYS A 432;HIS A 435;LEU A 436;PHE A 439","HXA A 200\r"],["2BYO_A_HXAA1215","2byo","HXA","Doconexent (DB03756)","Mycobacterium tuberculosis","LIPOPROTEIN LPPX","LppX_LprAFG",23,"ILE A  28;LEU A  32;THR A  35;LYS A  36;VAL A  41;VAL A  43;VAL A  64;GLY A 120;VAL A 121;GLN A 123;LEU A 125;VAL A 128;ILE A 147;THR A 148;GLY A 149;ILE A 151;ALA A 169;THR A 170;VAL A 171;LEU A 181;ALA A 184;LEU A 195;GLN A 197","HXA A1215\r"],["2G7Z_A_HXAA9136","2g7z","HXA","Doconexent (DB03756)","Streptococcus pyogenes","CONSERVED HYPOTHETICAL PROTEIN SPY1493","DegV",27,"LEU A  29;THR A  62;SER A  63;GLN A  64;LEU A  90;LEU A  94;SER A  95;GLY A  96;THR A  97;THR A 120;ASP A 121;LEU A 157;ILE A 159;ARG A 172;LEU A 192;LEU A 197;SER A 231;TYR A 232;ALA A 233;THR A 259;ILE A 262;ILE A 263;HIS A 266;THR A 267;ALA A 271;PHE A 272;ALA A 273","HXA A9136\r"],["2VV0_A_HXAA1476","2vv0","HXA","Doconexent (DB03756)","Homo sapiens","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","Hormone_recep",19,"ILE A 281;GLY A 284;CYS A 285;ARG A 288;SER A 289;HIS A 323;ILE A 326;TYR A 327;LEU A 330;VAL A 339;LEU A 340;ILE A 341;SER A 342;MET A 348;MET A 364;HIS A 449;LEU A 453;LEU A 469;TYR A 473","HXA A1476\r"],["3HS7_A_HXAA1","3hs7","HXA","Doconexent (DB03756)","Mus musculus","PROSTAGLANDIN G\/H SYNTHASE 2","An_peroxidase;EGF",27,"VAL A 116;ARG A 120;PHE A 205;PHE A 209;GLY A 227;VAL A 228;TYR A 348;VAL A 349;LEU A 352;SER A 353;TYR A 355;ASN A 375;ILE A 377;PHE A 381;LEU A 384;TYR A 385;TRP A 387;PHE A 518;MET A 522;VAL A 523;GLY A 526;ALA A 527;PHE A 529;SER A 530;LEU A 531;GLY A 533;LEU A 534","HXA A   1\r"],["5J0Z_A_HXAA408","5j0z","HXA","Doconexent (DB03756)","Gloeobacter violaceus (strain pcc 7421)","PROTON-GATED ION CHANNEL","NA",4,"ARG A 117;ARG A 118;PHE E 195;MET A 252","HXA A 408\r"],["5Y5C_B_HXAB201","5y5c","HXA","Doconexent (DB03756)","Bos taurus","BETA-LACTOGLOBULIN","Lipocalin",21,"PRO B  38;PRO A  38;VAL A  41;LEU A  46;LEU A  54;ILE A  56;LEU A  58;LYS B  60;GLU B  62;LYS B  69;LYS A  69;ILE A  71;ILE A  84;ASP A  85;LEU B  87;VAL A  92;VAL A  94;LEU A 103;PHE A 105;MET A 107;LEU A 122","HXA B 201\r"],["5Y5C_B_HXAB202","5y5c","HXA","Doconexent (DB03756)","Bos taurus","BETA-LACTOGLOBULIN","Lipocalin",19,"VAL B  41;VAL B  43;LEU B  46;ILE B  56;LEU B  58;ILE B  71;ILE B  84;ASP B  85;ALA A  86;LEU B  87;GLU A  89;ASN B  90;VAL B  92;LEU B 103;PHE B 105;MET B 107;ASN B 109;SER B 116;LEU B 122","HXA B 202\r"]]