Ligand ID: GD4

Drugbank ID:
Troglitazone
(DB00197)

Indication:
Troglitazone was withdrawn in 2000 due to risk of hepatotoxicity. It was superseded by pioglitazone and rosiglitazone.

LIST OF BINDING INTERFACES for query 'DB00197'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
6DGO_A_GD4A501	6dgo	GD4	Troglitazone (DB00197)	Homo sapiens	PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA	Hormone_recep	25	HIS A 266 ILE A 281 PHE A 282 GLY A 284 CYS A 285 PHE A 287 ARG A 288 SER A 289 HIS A 323 ILE A 326 TYR A 327 LEU A 330 VAL A 339 LEU A 340 ILE A 341 SER A 342 MET A 348 LEU A 353 MET A 364 LYS A 367 HIS A 449 LEU A 453 LEU A 465 LEU A 469 TYR A 473	GD4 A 501		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["6DGO_A_GD4A501","6dgo","GD4","Troglitazone (DB00197)","Homo sapiens","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","Hormone_recep",25,"HIS A 266;ILE A 281;PHE A 282;GLY A 284;CYS A 285;PHE A 287;ARG A 288;SER A 289;HIS A 323;ILE A 326;TYR A 327;LEU A 330;VAL A 339;LEU A 340;ILE A 341;SER A 342;MET A 348;LEU A 353;MET A 364;LYS A 367;HIS A 449;LEU A 453;LEU A 465;LEU A 469;TYR A 473","GD4 A 501\r"]]