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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 1dzm | BZM | Benzyl benzoate (DB00676) | Benzyl benzoate is a topical treatment for scabies and lice. | ODORANT-BINDING PROTEIN (Sus scrofa) | Lipocalin | ||
| 1h7x | URF | Fluorouracil (DB00544) | Fluorouracil is a pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment. | DIHYDROPYRIMIDINE DEHYDROGENASE (Sus scrofa) | DHO_dhFer4_20Fer4_21Pyr_redox_2 | ||
| 1js3 | 142 | Carbidopa (DB00190) | Carbidopa is a dopa decarboxylase inhibitor used in combination with levodopa for the symptomatic treatment of idiopathic Parkinson disease and other conditions associated with parkinsonian symptoms. | DOPA DECARBOXYLASE (Sus scrofa) | Pyridoxal_deC | ||
| 1tub | TXL | Docetaxel (DB01248) | Docetaxel is a taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer. | TUBULIN (Sus scrofa) | TubulinTubulin_C | ||
| 2azy | CHD | Cholic acid (DB02659) | Cholic Acid is a bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function. | PHOSPHOLIPASE A2, MAJOR ISOENZYME (Sus scrofa) | Phospholip_A2_1 | ||
| 3mth | MPB | Methylparaben (DB14212) | Methylparaben is used in allergenic testing. | METHYLPARABEN INSULIN (Sus scrofa) | NA | ||
| 3sfe | TMG | Thiabendazole (DB00730) | Thiabendazole is a benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections. | SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL;SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL;SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL (Sus scrofa) | Fer2_3Fer4_17Sdh_cyt | ||
| 4dbk | BER | Berberine (DB04115) | An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal... | PHOSPHOLIPASE A2, MAJOR ISOENZYME (Sus scrofa) | Phospholip_A2_1 | ||
| 6m11 | B49 | Sunitinib (DB01268) | Sunitinib is a receptor tyrosine kinase inhibitor and chemotherapeutic agent used for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). | RIBONUCLEASE L (Sus scrofa) | Ank_2Ank_3Ank_4PkinaseRibonuc_2-5A | ||
| 6wwr | TA1 | Paclitaxel (DB01229) | Paclitaxel is a taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer. | TUBULIN BETA-2B CHAIN (Mus musculus;sus scrofa) | TubulinTubulin_C | ||
| 7daf | GZX | Ixabepilone (DB04845) | Ixabepilone is a microtubule inhibitor administered in combination with capecitabine or alone in the treatment of metastatic or locally advanced breast cancer that has shown inadequate response to taxanes and anthracyclines. | TUBULIN BETA CHAIN (Mus musculus;gallus gallus;sus scrofa) | TubulinTubulin_C | ||
| 7ddh | DGX | Digoxin (DB00390) | Digoxin is a cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation. | SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1;SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1 (Sus scrofa) | Cation_ATPaseCation_ATPase_CCation_ATPase_NE1-E2_ATPaseNa_K-ATPase | ||
| 7ddi | F9R | Digitoxin (DB01396) | Digitoxin is a cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure. | SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1;SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1 (Sus scrofa) | Cation_ATPaseCation_ATPase_CCation_ATPase_NE1-E2_ATPaseNa_K-ATPase | ||
| 7ddj | OBN | Ouabain (DB01092) | A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. It is commonly used in cell... | SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1 (Sus scrofa) | Cation_ATPaseCation_ATPase_CCation_ATPase_NE1-E2_ATPase | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |