Ligand ID: TA1

Drugbank ID:
Paclitaxel
(DB01229)

Indication:
Paclitaxel is a taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer.

LIST OF BINDING INTERFACES for query 'TA1'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
5W3J_B_TA1B502	5w3j	TA1	Paclitaxel (DB01229)	Saccharomyces cerevisiae (strain atcc 204508 / s288c)	TUBULIN BETA CHAIN	Tubulin Tubulin_C	13	GLU B  22 VAL B  23 ASP B  26 GLU B  27 HIS B 227 LEU B 228 THR B 274 ILE B 276 GLN B 279 PRO B 358 GLN B 359 GLY B 360 LEU B 361	TA1 B 502		Details
6QEX_A_TA1A1320	6qex	TA1	Paclitaxel (DB01229)	Homo sapiens; mus musculus	MULTIDRUG RESISTANCE PROTEIN 1	ABC_membrane ABC_tran	25	MET A  68 MET A  69 TRP A 232 PHE A 303 ILE A 306 TYR A 307 TYR A 310 PHE A 336 LEU A 339 ILE A 340 PHE A 343 SER A 344 GLN A 347 GLN A 725 PHE A 728 ALA A 871 GLU A 875 GLN A 946 MET A 949 TYR A 953 VAL A 982 PHE A 983 MET A 986 ALA A 987 GLN A 990	TA1 A1320		Details
6WWR_B_TA1B502	6wwr	TA1	Paclitaxel (DB01229)	Mus musculus; sus scrofa	TUBULIN BETA-2B CHAIN	Tubulin Tubulin_C	21	GLU B  22 VAL B  23 ASP B  26 GLU B  27 LEU B 215 ASP B 224 HIS B 227 LEU B 228 ALA B 231 SER B 234 PHE B 270 PRO B 272 LEU B 273 THR B 274 ARG B 276 GLN B 279 ARG B 318 PRO B 358 ARG B 359 GLY B 360 LEU B 361	TA1 B 502		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["5W3J_B_TA1B502","5w3j","TA1","Paclitaxel (DB01229)","Saccharomyces cerevisiae (strain atcc 204508 \/ s288c)","TUBULIN BETA CHAIN","Tubulin;Tubulin_C",13,"GLU B 22;VAL B 23;ASP B 26;GLU B 27;HIS B 227;LEU B 228;THR B 274;ILE B 276;GLN B 279;PRO B 358;GLN B 359;GLY B 360;LEU B 361","TA1 B 502\r"],["6QEX_A_TA1A1320","6qex","TA1","Paclitaxel (DB01229)","Homo sapiens;mus musculus","MULTIDRUG RESISTANCE PROTEIN 1","ABC_membrane;ABC_tran",25,"MET A 68;MET A 69;TRP A 232;PHE A 303;ILE A 306;TYR A 307;TYR A 310;PHE A 336;LEU A 339;ILE A 340;PHE A 343;SER A 344;GLN A 347;GLN A 725;PHE A 728;ALA A 871;GLU A 875;GLN A 946;MET A 949;TYR A 953;VAL A 982;PHE A 983;MET A 986;ALA A 987;GLN A 990","TA1 A1320\r"],["6WWR_B_TA1B502","6wwr","TA1","Paclitaxel (DB01229)","Mus musculus;sus scrofa","TUBULIN BETA-2B CHAIN","Tubulin;Tubulin_C",21,"GLU B 22;VAL B 23;ASP B 26;GLU B 27;LEU B 215;ASP B 224;HIS B 227;LEU B 228;ALA B 231;SER B 234;PHE B 270;PRO B 272;LEU B 273;THR B 274;ARG B 276;GLN B 279;ARG B 318;PRO B 358;ARG B 359;GLY B 360;LEU B 361","TA1 B 502\r"]]