LIST OF BINDING INTERFACES for query 'Naegleria fowleri' in category 'SOURCE ORGANISM'

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PDB Ligand Drug Indication Macromolecule/
Organism
Pfam Binding_Interfaces (View) Details
5tl8 X2NPosaconazole
(DB01263)
Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.PROTEIN CYP51
(Naegleria fowleri)
p450
6ay4 TPFFluconazole
(DB00196)
Fluconazole is a triazole antifungal used to treat various fungal infections including candidiasis.CYP51, STEROL 14ALPHA-DEMETHYLASE
(Naegleria fowleri)
p450
6ay6 VORVoriconazole
(DB00582)
Voriconazole is a triazole compound used to treat fungal infections.CYP51, STEROL 14ALPHA-DEMETHYLASE
(Naegleria fowleri)
p450
6ayb KKKKetoconazole
(DB01026)
Ketoconazole is a broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.CYP51, STEROL 14ALPHA-DEMETHYLASE
(Naegleria fowleri)
p450
6ayc 1YNItraconazole
(DB01167)
Itraconazole is an antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.PROTEIN CYP51
(Naegleria fowleri)
p450
6mke FK5Tacrolimus
(DB00864)
Tacrolimus is a calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis.PEPTIDYLPROLYL ISOMERASE
(Naegleria fowleri)
FKBP_C
6uyh HFGHalofuginone
(DB04866)
Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis...PROLYL-TRNA SYNTHETASE
(Naegleria fowleri)
HGTP_anticodon
ProRS-C_1
tRNA-synt_2b
PDB Ligand Drug Indication Macromolecule/
Organism
Pfam Binding_Interfaces (View) Details