Ligand ID: KKK

Drugbank ID:
Ketoconazole
(DB01026)

Indication:
Ketoconazole is a broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.

LIST OF BINDING INTERFACES for query 'KKK'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3LD6_A_KKKA602	3ld6	KKK	Ketoconazole (DB01026)	Homo sapiens	LANOSTEROL 14-ALPHA DEMETHYLASE	p450	17	PHE A  77 PHE A 105 TYR A 131 LEU A 134 THR A 135 PHE A 139 TYR A 145 PHE A 234 HIS A 236 TRP A 239 GLY A 307 ALA A 311 THR A 315 ILE A 377 ILE A 379 MET A 381 MET A 487	KKK A 602		Details
3OZW_A_KKKA413	3ozw	KKK	Ketoconazole (DB01026)	Ralstonia eutropha	FLAVOHEMOGLOBIN	FAD_binding_6 Globin NAD_binding_1	16	ILE A  25 PHE A  28 TYR A  29 PHE A  43 ASN A  44 ALA A  46 GLN A  50 GLN A  52 GLN A  53 ALA A  56 LEU A  57 HIS A  85 VAL A  98 LEU A 102 GLY A 397 PRO A 398	KKK A 413		Details
5LI8_A_KKKA502	5li8	KKK	Ketoconazole (DB01026)	Mycobacterium tuberculosis (strain cdc 1551 / oshkosh)	PUTATIVE CYTOCHROME P450 126	p450	21	LEU A  12 THR A  13 PRO A  46 PHE A  51 VAL A  94 ASN A  96 PHE A 246 LEU A 249 LEU A 250 ALA A 253 GLY A 254 THR A 257 SER A 300 SER A 302 LYS A 303 ARG A 304 VAL A 325 TRP A 327 CYS A 363 ASN A 399 ARG A 400	KKK A 502		Details
6AYB_A_KKKA508	6ayb	KKK	Ketoconazole (DB01026)	Naegleria fowleri	CYP51, STEROL 14ALPHA-DEMETHYLASE	p450	21	PHE A  53 PRO A  57 TYR A 107 PHE A 109 MET A 110 PHE A 114 VAL A 119 TYR A 120 PRO A 213 PHE A 216 PHE A 217 ALA A 289 GLY A 290 PHE A 292 ALA A 293 THR A 297 LEU A 358 ILE A 359 MET A 360 MET A 362 LEU A 467	KKK A 508		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3LD6_A_KKKA602","3ld6","KKK","Ketoconazole (DB01026)","Homo sapiens","LANOSTEROL 14-ALPHA DEMETHYLASE","p450",17,"PHE A 77;PHE A 105;TYR A 131;LEU A 134;THR A 135;PHE A 139;TYR A 145;PHE A 234;HIS A 236;TRP A 239;GLY A 307;ALA A 311;THR A 315;ILE A 377;ILE A 379;MET A 381;MET A 487","KKK A 602\r"],["3OZW_A_KKKA413","3ozw","KKK","Ketoconazole (DB01026)","Ralstonia eutropha","FLAVOHEMOGLOBIN","FAD_binding_6;Globin;NAD_binding_1",16,"ILE A 25;PHE A 28;TYR A 29;PHE A 43;ASN A 44;ALA A 46;GLN A 50;GLN A 52;GLN A 53;ALA A 56;LEU A 57;HIS A 85;VAL A 98;LEU A 102;GLY A 397;PRO A 398","KKK A 413\r"],["5LI8_A_KKKA502","5li8","KKK","Ketoconazole (DB01026)","Mycobacterium tuberculosis (strain cdc 1551 \/ oshkosh)","PUTATIVE CYTOCHROME P450 126","p450",21,"LEU A 12;THR A 13;PRO A 46;PHE A 51;VAL A 94;ASN A 96;PHE A 246;LEU A 249;LEU A 250;ALA A 253;GLY A 254;THR A 257;SER A 300;SER A 302;LYS A 303;ARG A 304;VAL A 325;TRP A 327;CYS A 363;ASN A 399;ARG A 400","KKK A 502\r"],["6AYB_A_KKKA508","6ayb","KKK","Ketoconazole (DB01026)","Naegleria fowleri","CYP51, STEROL 14ALPHA-DEMETHYLASE","p450",21,"PHE A 53;PRO A 57;TYR A 107;PHE A 109;MET A 110;PHE A 114;VAL A 119;TYR A 120;PRO A 213;PHE A 216;PHE A 217;ALA A 289;GLY A 290;PHE A 292;ALA A 293;THR A 297;LEU A 358;ILE A 359;MET A 360;MET A 362;LEU A 467","KKK A 508\r"]]