Ligand ID: VOR

Drugbank ID:
Voriconazole
(DB00582)

Indication:
Voriconazole is a triazole compound used to treat fungal infections.

LIST OF BINDING INTERFACES for query 'DB00582'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3MDT_A_VORA506	3mdt	VOR	Voriconazole (DB00582)	Homo sapiens	CHOLESTEROL 24-HYDROXYLASE	NA	14	TYR A 109 LEU A 112 PHE A 121 VAL A 126 SER A 127 LEU A 219 ILE A 222 ILE A 301 ALA A 302 THR A 306 ALA A 367 CYS A 437 ALA A 474 THR A 475	VOR A 506		Details
4UYM_A_VORA590	4uym	VOR	Voriconazole (DB00582)	Aspergillus fumigatus	14-ALPHA STEROL DEMETHYLASE	p450	13	TYR A 122 PHE A 130 VAL A 135 TYR A 136 ALA A 303 ALA A 307 SER A 311 ILE A 373 SER A 375 ILE A 376 CYS A 463 LEU A 503 PHE A 504	VOR A 590		Details
5HS1_A_VORA602	5hs1	VOR	Voriconazole (DB00582)	Saccharomyces cerevisiae	LANOSTEROL 14-ALPHA DEMETHYLASE	p450	15	TYR A 126 THR A 130 PHE A 134 ILE A 139 TYR A 140 PHE A 236 GLY A 310 VAL A 311 GLY A 314 GLY A 315 THR A 318 LEU A 380 SER A 382 LEU A 383 MET A 509	VOR A 602		Details
6AY6_A_VORA501	6ay6	VOR	Voriconazole (DB00582)	Naegleria fowleri	CYP51, STEROL 14ALPHA-DEMETHYLASE	p450	14	TYR A 107 MET A 110 PHE A 114 VAL A 119 TYR A 120 ALA A 289 GLY A 290 PHE A 292 ALA A 293 THR A 297 LEU A 358 MET A 360 CYS A 430 LEU A 467	VOR A 501		Details
6H1O_A_VORA502	6h1o	VOR	Voriconazole (DB00582)	Bacillus megaterium	BIFUNCTIONAL CYTOCHROME P450/NADPH--P450 REDUCTASE	p450	14	LEU A  75 VAL A  78 PHE A  82 VAL A  87 THR A  88 MET A 177 LEU A 181 THR A 260 ILE A 263 ALA A 264 GLU A 267 THR A 268 LEU A 437 THR A 438	VOR A 502		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3MDT_A_VORA506","3mdt","VOR","Voriconazole (DB00582)","Homo sapiens","CHOLESTEROL 24-HYDROXYLASE","NA",14,"TYR A 109;LEU A 112;PHE A 121;VAL A 126;SER A 127;LEU A 219;ILE A 222;ILE A 301;ALA A 302;THR A 306;ALA A 367;CYS A 437;ALA A 474;THR A 475","VOR A 506\r"],["4UYM_A_VORA590","4uym","VOR","Voriconazole (DB00582)","Aspergillus fumigatus","14-ALPHA STEROL DEMETHYLASE","p450",13,"TYR A 122;PHE A 130;VAL A 135;TYR A 136;ALA A 303;ALA A 307;SER A 311;ILE A 373;SER A 375;ILE A 376;CYS A 463;LEU A 503;PHE A 504","VOR A 590\r"],["5HS1_A_VORA602","5hs1","VOR","Voriconazole (DB00582)","Saccharomyces cerevisiae","LANOSTEROL 14-ALPHA DEMETHYLASE","p450",15,"TYR A 126;THR A 130;PHE A 134;ILE A 139;TYR A 140;PHE A 236;GLY A 310;VAL A 311;GLY A 314;GLY A 315;THR A 318;LEU A 380;SER A 382;LEU A 383;MET A 509","VOR A 602\r"],["6AY6_A_VORA501","6ay6","VOR","Voriconazole (DB00582)","Naegleria fowleri","CYP51, STEROL 14ALPHA-DEMETHYLASE","p450",14,"TYR A 107;MET A 110;PHE A 114;VAL A 119;TYR A 120;ALA A 289;GLY A 290;PHE A 292;ALA A 293;THR A 297;LEU A 358;MET A 360;CYS A 430;LEU A 467","VOR A 501\r"],["6H1O_A_VORA502","6h1o","VOR","Voriconazole (DB00582)","Bacillus megaterium","BIFUNCTIONAL CYTOCHROME P450\/NADPH--P450 REDUCTASE","p450",14,"LEU A 75;VAL A 78;PHE A 82;VAL A 87;THR A 88;MET A 177;LEU A 181;THR A 260;ILE A 263;ALA A 264;GLU A 267;THR A 268;LEU A 437;THR A 438","VOR A 502\r"]]