LIST OF BINDING INTERFACES for query 'Mycobacterium tuberculosis (strain atcc 25618 / h37rv)' in category 'SOURCE ORGANISM'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details
4xt7	TOP	Trimethoprim (DB00440)	Trimethoprim is an antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract.	RV2671 (Mycobacterium tuberculosis (strain atcc 25618 / h37rv))	RibD_C	4XT7_A_TOPA302	Details
4xt8	TMQ	Trimetrexate (DB01157)	Trimetrexate is a folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin.	RV2671 (Mycobacterium tuberculosis (strain atcc 25618 / h37rv))	RibD_C	4XT8_A_TMQA302	Details
5yk2	ERY	Erythromycin (DB00199)	Erythromycin is a macrolide antibiotic used to treat and prevent a variety of bacterial infections.	PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER (Mycobacterium tuberculosis (strain atcc 25618 / h37rv))	ABC1	5YK2_A_ERYA501	Details
6b6d	9F2	Ceftriaxone (DB01212)	Ceftriaxone is a broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract.	BETA-LACTAMASE (Mycobacterium tuberculosis (strain atcc 25618 / h37rv))	Beta-lactamase2	6B6D_A_9F2A302	Details
6fbv	FI8	Fidaxomicin (DB08874)	Fidaxomicin is a macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection.	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA; DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'; RNA POLYMERASE SIGMA FACTOR SIGA (Mycobacterium tuberculosis (strain atcc 25618 / h37rv))	RNA_pol_Rpb1_1 RNA_pol_Rpb1_2 RNA_pol_Rpb1_3 RNA_pol_Rpb1_4 RNA_pol_Rpb1_5 RNA_pol_Rpb2_1 RNA_pol_Rpb2_2 RNA_pol_Rpb2_3 RNA_pol_Rpb2_45 RNA_pol_Rpb2_6 RNA_pol_Rpb2_7 Sigma70_r1_2 Sigma70_r2 Sigma70_r3 Sigma70_r4	6FBV_D_FI8D1904	Details
6kgu	AZR	Aztreonam (DB00355)	Aztreonam is a beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria.	PENICILLIN-BINDING PROTEIN PBPB (Mycobacterium tuberculosis (strain atcc 25618 / h37rv))	PBP_dimer Transpeptidase	6KGU_A_AZRA701	Details
6nl4	GEO	Gemcitabine (DB00441)	Gemcitabine is a nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer.	ATP-DEPENDENT DETHIOBIOTIN SYNTHETASE BIOD (Mycobacterium tuberculosis (strain atcc 25618 / h37rv))	AAA_26	6NL4_A_GEOA302	Details
6za5	SAL	Salicylic acid (DB00936)	Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.	SALICYLATE SYNTHASE (Mycobacterium tuberculosis (strain atcc 25618 / h37rv))	Chorismate_bind	6ZA5_B_SALB502	Details
PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details

[["4xt7","TOP","Trimethoprim (DB00440)","Mycobacterium tuberculosis (strain atcc 25618 \/ h37rv)","RV2671","RibD_C"],["4xt8","TMQ","Trimetrexate (DB01157)","Mycobacterium tuberculosis (strain atcc 25618 \/ h37rv)","RV2671","RibD_C"],["5yk2","ERY","Erythromycin (DB00199)","Mycobacterium tuberculosis (strain atcc 25618 \/ h37rv)","PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER","ABC1"],["6b6d","9F2","Ceftriaxone (DB01212)","Mycobacterium tuberculosis (strain atcc 25618 \/ h37rv)","BETA-LACTAMASE","Beta-lactamase2"],["6fbv","FI8","Fidaxomicin (DB08874)","Mycobacterium tuberculosis (strain atcc 25618 \/ h37rv)","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA;DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA';RNA POLYMERASE SIGMA FACTOR SIGA","RNA_pol_Rpb1_1;RNA_pol_Rpb1_2;RNA_pol_Rpb1_3;RNA_pol_Rpb1_4;RNA_pol_Rpb1_5;RNA_pol_Rpb2_1;RNA_pol_Rpb2_2;RNA_pol_Rpb2_3;RNA_pol_Rpb2_45;RNA_pol_Rpb2_6;RNA_pol_Rpb2_7;Sigma70_r1_2;Sigma70_r2;Sigma70_r3;Sigma70_r4"],["6kgu","AZR","Aztreonam (DB00355)","Mycobacterium tuberculosis (strain atcc 25618 \/ h37rv)","PENICILLIN-BINDING PROTEIN PBPB","PBP_dimer;Transpeptidase"],["6nl4","GEO","Gemcitabine (DB00441)","Mycobacterium tuberculosis (strain atcc 25618 \/ h37rv)","ATP-DEPENDENT DETHIOBIOTIN SYNTHETASE BIOD","AAA_26"],["6za5","SAL","Salicylic acid (DB00936)","Mycobacterium tuberculosis (strain atcc 25618 \/ h37rv)","SALICYLATE SYNTHASE","Chorismate_bind"]]