Results: Ligand

Ligand ID: FI8

Drugbank ID:
Fidaxomicin
(DB08874)

Indication:
Fidaxomicin is a macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection.

LIST OF BINDING INTERFACES for query 'DB08874'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
6BZO_C_FI8C1201	6bzo	FI8	Fidaxomicin (DB08874)	Mycobacterium tuberculosis; synthetic construct	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA; DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'; RNA POLYMERASE SIGMA FACTOR SIGA; RNA POLYMERASE-BINDING PROTEIN RBPA	RNA_pol_Rpb1_1 RNA_pol_Rpb1_2 RNA_pol_Rpb1_3 RNA_pol_Rpb1_4 RNA_pol_Rpb1_5 RNA_pol_Rpb2_1 RNA_pol_Rpb2_2 RNA_pol_Rpb2_3 RNA_pol_Rpb2_45 RNA_pol_Rpb2_6 RNA_pol_Rpb2_7 RbpA Sigma70_r1_2 Sigma70_r2 Sigma70_r3 Sigma70_r4	33	ARG J 10 VAL J 14 ASP D 57 ARG D 84 ALA D 85 LYS D 86 ARG D 89 GLU D 323 LEU D 324 PRO D 326 SER D 338 LEU D 405 ARG D 412 GLN D 415 LEU F 423 ASP F 424 GLN F 434 VAL F 445 ALA F 450 MET C1051 ILE C1052 THR C1053 GLN C1054 ASP C1094 ASP C1095 THR C1096 VAL C1097 VAL C1100 LYS C1101 GLU C1119 SER C1120 VAL C1123 GLU C1127	FI8 C1201
6FBV_D_FI8D1904	6fbv	FI8	Fidaxomicin (DB08874)	Mycobacterium tuberculosis (strain atcc 25618 / h37rv)	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA; DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'; RNA POLYMERASE SIGMA FACTOR SIGA	RNA_pol_Rpb1_1 RNA_pol_Rpb1_2 RNA_pol_Rpb1_3 RNA_pol_Rpb1_4 RNA_pol_Rpb1_5 RNA_pol_Rpb2_1 RNA_pol_Rpb2_2 RNA_pol_Rpb2_3 RNA_pol_Rpb2_45 RNA_pol_Rpb2_6 RNA_pol_Rpb2_7 Sigma70_r1_2 Sigma70_r2 Sigma70_r3 Sigma70_r4	26	ASP D 57 ARG D 84 ALA D 85 LYS D 86 ARG D 89 GLU D 323 LEU D 324 PRO D 326 VAL D 328 SER D 338 LEU D 405 ARG D 412 GLN D 415 LEU F 423 ASP F 424 MET C1051 ILE C1052 GLN C1054 ASP C1094 ASP C1095 THR C1096 VAL C1097 VAL C1100 LYS C1101 GLU C1119 SER C1120	FI8 D1904
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["6BZO_C_FI8C1201","6bzo","FI8","Fidaxomicin (DB08874)","Mycobacterium tuberculosis;synthetic construct","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA;DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA';RNA POLYMERASE SIGMA FACTOR SIGA;RNA POLYMERASE-BINDING PROTEIN RBPA","RNA_pol_Rpb1_1;RNA_pol_Rpb1_2;RNA_pol_Rpb1_3;RNA_pol_Rpb1_4;RNA_pol_Rpb1_5;RNA_pol_Rpb2_1;RNA_pol_Rpb2_2;RNA_pol_Rpb2_3;RNA_pol_Rpb2_45;RNA_pol_Rpb2_6;RNA_pol_Rpb2_7;RbpA;Sigma70_r1_2;Sigma70_r2;Sigma70_r3;Sigma70_r4",33,"ARG J  10;VAL J  14;ASP D  57;ARG D  84;ALA D  85;LYS D  86;ARG D  89;GLU D 323;LEU D 324;PRO D 326;SER D 338;LEU D 405;ARG D 412;GLN D 415;LEU F 423;ASP F 424;GLN F 434;VAL F 445;ALA F 450;MET C1051;ILE C1052;THR C1053;GLN C1054;ASP C1094;ASP C1095;THR C1096;VAL C1097;VAL C1100;LYS C1101;GLU C1119;SER C1120;VAL C1123;GLU C1127","FI8 C1201\r"],["6FBV_D_FI8D1904","6fbv","FI8","Fidaxomicin (DB08874)","Mycobacterium tuberculosis (strain atcc 25618 \/ h37rv)","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA;DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA';RNA POLYMERASE SIGMA FACTOR SIGA","RNA_pol_Rpb1_1;RNA_pol_Rpb1_2;RNA_pol_Rpb1_3;RNA_pol_Rpb1_4;RNA_pol_Rpb1_5;RNA_pol_Rpb2_1;RNA_pol_Rpb2_2;RNA_pol_Rpb2_3;RNA_pol_Rpb2_45;RNA_pol_Rpb2_6;RNA_pol_Rpb2_7;Sigma70_r1_2;Sigma70_r2;Sigma70_r3;Sigma70_r4",26,"ASP D  57;ARG D  84;ALA D  85;LYS D  86;ARG D  89;GLU D 323;LEU D 324;PRO D 326;VAL D 328;SER D 338;LEU D 405;ARG D 412;GLN D 415;LEU F 423;ASP F 424;MET C1051;ILE C1052;GLN C1054;ASP C1094;ASP C1095;THR C1096;VAL C1097;VAL C1100;LYS C1101;GLU C1119;SER C1120","FI8 D1904\r"]]