Results: Keyword

LIST OF BINDING INTERFACES for query 'Human immunodeficiency virus 1' in category 'SOURCE ORGANISM'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details
1c6y	MK1	Indinavir (DB00224)	Indinavir is a protease inhibitor used to treat HIV infection.	PROTEIN (PROTEASE) (Human immunodeficiency virus 1)	RVP	1C6Y_B_MK1B524
1c6z	ROC	Saquinavir (DB01232)	Saquinavir is an HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.	PROTEIN (PROTEASE) (Human immunodeficiency virus 1)	RVP	1C6Z_B_ROCB505
1klm	SPP	Delavirdine (DB00705)	Delavirdine is a non-nucleoside reverse transcriptase inhibitor used to treat HIV infection.	HIV-1 REVERSE TRANSCRIPTASE (Human immunodeficiency virus 1)	RNase_H RVT_1 RVT_connect RVT_thumb	1KLM_A_SPPA999
1rl8	RIT	Ritonavir (DB00503)	Ritonavir is an HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.	PROTEASE RETROPEPSIN (Human immunodeficiency virus 1)	RVP	1RL8_A_RITA9001
1sdv	MK1	Indinavir (DB00224)	Indinavir is a protease inhibitor used to treat HIV infection.	PROTEASE RETROPEPSIN (Human immunodeficiency virus 1)	RVP	1SDV_B_MK1B902
1sgu	MK1	Indinavir (DB00224)	Indinavir is a protease inhibitor used to treat HIV infection.	POL POLYPROTEIN (Human immunodeficiency virus 1)	RVP	1SGU_B_MK1B2632
2aof	FRD	Amphetamine (DB00182)	Amphetamine is a CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).	PEPTIDE INHIBITOR; POL POLYPROTEIN (Human immunodeficiency virus 1; synthetic construct)	RVP	2AOF_C_FRDC305
2avo	MK1	Indinavir (DB00224)	Indinavir is a protease inhibitor used to treat HIV infection.	POL POLYPROTEIN (Human immunodeficiency virus 1)	RVP	2AVO_B_MK1B902
2b60	RIT	Ritonavir (DB00503)	Ritonavir is an HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.	GAG-POL POLYPROTEIN (Human immunodeficiency virus 1)	RVP	2B60_B_RITB100
2b7z	MK1	Indinavir (DB00224)	Indinavir is a protease inhibitor used to treat HIV infection.	HIV-1 PROTEASE (Human immunodeficiency virus 1)	RVP	2B7Z_B_MK1B200
2fxd	DR7	Atazanavir (DB01072)	Atazanavir is an antiviral protease inhibitor used in combination with other antiretrovirals for the treatment of HIV.	POL PROTEIN (Human immunodeficiency virus 1)	RVP	2FXD_A_DR7A102
2hs1	017	Darunavir (DB01264)	Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.	HIV-1 PROTEASE (Human immunodeficiency virus 1)	RVP	2HS1_A_017A201
2idw	017	Darunavir (DB01264)	Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.	PROTEASE (Human immunodeficiency virus 1)	RVP	2IDW_B_017B401
2nmz	ROC	Saquinavir (DB01232)	Saquinavir is an HIV protease inhibitor used in combination with other antiretroviral agents for the treatment of HIV-1 with advanced immunodeficiency.	PROTEASE (Human immunodeficiency virus 1)	RVP	2NMZ_B_ROCB401
2r5p	MK1	Indinavir (DB00224)	Indinavir is a protease inhibitor used to treat HIV infection.	PROTEASE (Human immunodeficiency virus 1)	RVP	2R5P_B_MK1B902
2r5q	1UN	Nelfinavir (DB00220)	Nelfinavir is a viral protease inhibitor used in the treatment of HIV infection.	PROTEASE (Human immunodeficiency virus 1)	RVP	2R5Q_B_1UNB900
2rkf	AB1	Lopinavir (DB01601)	Lopinavir is an HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.	PROTEASE RETROPEPSIN (Human immunodeficiency virus 1)	RVP	2RKF_A_AB1A501
3lzu	017	Darunavir (DB01264)	Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.	HIV-1 PROTEASE (Human immunodeficiency virus 1)	RVP	3LZU_A_017A200
3mws	017	Darunavir (DB01264)	Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.	HIV-1 PROTEASE (Human immunodeficiency virus 1)	RVP	3MWS_B_017B201
3ndx	RIT	Ritonavir (DB00503)	Ritonavir is an HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.	PROTEASE (Human immunodeficiency virus 1)	RVP	3NDX_A_RITA100
3nu3	478	Amprenavir (DB00701)	Amprenavir is a protease inhibitor used to treat HIV infection.	PROTEASE (Human immunodeficiency virus 1)	RVP	3NU3_B_478B401
3u7s	017	Darunavir (DB01264)	Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.	POL POLYPROTEIN (Human immunodeficiency virus 1)	RVP	3U7S_A_017A201 3U7S_A_017A202
3ucb	017	Darunavir (DB01264)	Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.	PROTEASE (Human immunodeficiency virus 1)	RVP	3UCB_A_017A201
4eyr	RIT	Ritonavir (DB00503)	Ritonavir is an HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.	HIV-1 PROTEASE (Human immunodeficiency virus 1)	RVP	4EYR_B_RITB301
4j5j	478	Amprenavir (DB00701)	Amprenavir is a protease inhibitor used to treat HIV infection.	PROTEASE (Human immunodeficiency virus 1)	RVP	4J5J_B_478B401 4J5J_B_478B402
4l1a	AB1	Lopinavir (DB01601)	Lopinavir is an HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.	MDR769 HIV-1 PROTEASE (Human immunodeficiency virus 1)	RVP	4L1A_A_AB1A101
4laj	ACA	Aminocaproic acid (DB00513)	Aminocaproic acid is an antifibrinolytic agent used to induce clotting postoperatively.	HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN (Human immunodeficiency virus 1; lama glama; synthetic construct)	NA	4LAJ_B_ACAB512
4ncg	2KW	Doravirine (DB12301)	Doravirine is a non-nucleoside reverse transcriptase inhibitor used in combination with other antiretrovirals to treat HIV-1 infections.	REVERSE TRANSCRIPTASE/RIBONUCLEASE H (Human immunodeficiency virus 1)	RNase_H RVT_1 RVT_connect RVT_thumb	4NCG_A_2KWA601
4njt	017	Darunavir (DB01264)	Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.	PROTEASE (Human immunodeficiency virus 1)	RVP	4NJT_B_017B101
4nju	TPV	Tipranavir (DB00932)	Tipranavir is a protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor.	PROTEASE (Human immunodeficiency virus 1)	RVP	4NJU_A_TPVA500
4njv	RIT	Ritonavir (DB00503)	Ritonavir is an HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection.	PROTEASE (Human immunodeficiency virus 1)	RVP	4NJV_A_RITA500
4npt	017	Darunavir (DB01264)	Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.	PROTEASE (Human immunodeficiency virus 1)	RVP	4NPT_A_017A401
4q1y	017	Darunavir (DB01264)	Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.	ASPARTYL PROTEASE (Human immunodeficiency virus 1)	RVP	4Q1Y_A_017A106
4rvj	478	Amprenavir (DB00701)	Amprenavir is a protease inhibitor used to treat HIV infection.	HIV-1 PROTEASE (Human immunodeficiency virus 1)	RVP	4RVJ_B_478B101
4yoa	017	Darunavir (DB01264)	Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.	HIV-1 PROTEASE (Human immunodeficiency virus 1)	RVP	4YOA_A_017A100
5t2z	017	Darunavir (DB01264)	Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.	PROTEASE (Human immunodeficiency virus 1)	NA	5T2Z_B_017B201
6bsg	EFZ	Efavirenz (DB00625)	Efavirenz is a non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.	REVERSE TRANSCRIPTASE P66 SUBUNIT (Human immunodeficiency virus 1; synthetic construct)	RNase_H RVT_1 RVT_connect RVT_thumb	6BSG_A_EFZA601
6dif	TPV	Tipranavir (DB00932)	Tipranavir is a protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor.	HIV-1 PROTEASE (Human immunodeficiency virus 1)	RVP	6DIF_B_TPVB201
6dj1	AB1	Lopinavir (DB01601)	Lopinavir is an HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.	HIV-1 PROTEASE (Human immunodeficiency virus 1)	RVP	6DJ1_B_AB1B201
6g9i	CXX	Clomipramine (DB01242)	Clomipramine is a tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder.	ENVELOPE GLYCOPROTEIN (Ebola virus - mayinga; zaire; 1976; human immunodeficiency virus 1)	NA	6G9I_B_CXXB707
6opv	017	Darunavir (DB01264)	Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.	PROTEASE NL4-3 (Human immunodeficiency virus 1)	RVP	6OPV_B_017B101
6puw	KLQ	Bictegravir (DB11799)	Bictegravir is an integrase inhibitor used to treat HIV infections.	CHIMERIC SSO7D AND HIV-1 INTEGRASE (Saccharolobus solfataricus (strain atcc 35092 / dsm 1617 / jcm 11322 / p2); human immunodeficiency virus 1; synthetic construct)	7kD_DNA_binding IN_DBD_C Integrase_Zn rve	6PUW_A_KLQA304
6vdk	DLU	Dolutegravir (DB08930)	Dolutegravir is an antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents.	INTEGRASE (Human immunodeficiency virus 1; synthetic construct)	IN_DBD_C Integrase_Zn rve	6VDK_A_DLUA303
PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details

[["1c6y","MK1","Indinavir (DB00224)","Human immunodeficiency virus 1","PROTEIN (PROTEASE)","RVP"],["1c6z","ROC","Saquinavir (DB01232)","Human immunodeficiency virus 1","PROTEIN (PROTEASE)","RVP"],["1klm","SPP","Delavirdine (DB00705)","Human immunodeficiency virus 1","HIV-1 REVERSE TRANSCRIPTASE","RNase_H;RVT_1;RVT_connect;RVT_thumb"],["1rl8","RIT","Ritonavir (DB00503)","Human immunodeficiency virus 1","PROTEASE RETROPEPSIN","RVP"],["1sdv","MK1","Indinavir (DB00224)","Human immunodeficiency virus 1","PROTEASE RETROPEPSIN","RVP"],["1sgu","MK1","Indinavir (DB00224)","Human immunodeficiency virus 1","POL POLYPROTEIN","RVP"],["2aof","FRD","Amphetamine (DB00182)","Human immunodeficiency virus 1;synthetic construct","PEPTIDE INHIBITOR;POL POLYPROTEIN","RVP"],["2avo","MK1","Indinavir (DB00224)","Human immunodeficiency virus 1","POL POLYPROTEIN","RVP"],["2b60","RIT","Ritonavir (DB00503)","Human immunodeficiency virus 1","GAG-POL POLYPROTEIN","RVP"],["2b7z","MK1","Indinavir (DB00224)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP"],["2fxd","DR7","Atazanavir (DB01072)","Human immunodeficiency virus 1","POL PROTEIN","RVP"],["2hs1","017","Darunavir (DB01264)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP"],["2idw","017","Darunavir (DB01264)","Human immunodeficiency virus 1","PROTEASE","RVP"],["2nmz","ROC","Saquinavir (DB01232)","Human immunodeficiency virus 1","PROTEASE","RVP"],["2r5p","MK1","Indinavir (DB00224)","Human immunodeficiency virus 1","PROTEASE","RVP"],["2r5q","1UN","Nelfinavir (DB00220)","Human immunodeficiency virus 1","PROTEASE","RVP"],["2rkf","AB1","Lopinavir (DB01601)","Human immunodeficiency virus 1","PROTEASE RETROPEPSIN","RVP"],["3lzu","017","Darunavir (DB01264)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP"],["3mws","017","Darunavir (DB01264)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP"],["3ndx","RIT","Ritonavir (DB00503)","Human immunodeficiency virus 1","PROTEASE","RVP"],["3nu3","478","Amprenavir (DB00701)","Human immunodeficiency virus 1","PROTEASE","RVP"],["3u7s","017","Darunavir (DB01264)","Human immunodeficiency virus 1","POL POLYPROTEIN","RVP"],["3ucb","017","Darunavir (DB01264)","Human immunodeficiency virus 1","PROTEASE","RVP"],["4eyr","RIT","Ritonavir (DB00503)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP"],["4j5j","478","Amprenavir (DB00701)","Human immunodeficiency virus 1","PROTEASE","RVP"],["4l1a","AB1","Lopinavir (DB01601)","Human immunodeficiency virus 1","MDR769 HIV-1 PROTEASE","RVP"],["4laj","ACA","Aminocaproic acid (DB00513)","Human immunodeficiency virus 1;lama glama;synthetic construct","HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN","NA"],["4ncg","2KW","Doravirine (DB12301)","Human immunodeficiency virus 1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","RNase_H;RVT_1;RVT_connect;RVT_thumb"],["4njt","017","Darunavir (DB01264)","Human immunodeficiency virus 1","PROTEASE","RVP"],["4nju","TPV","Tipranavir (DB00932)","Human immunodeficiency virus 1","PROTEASE","RVP"],["4njv","RIT","Ritonavir (DB00503)","Human immunodeficiency virus 1","PROTEASE","RVP"],["4npt","017","Darunavir (DB01264)","Human immunodeficiency virus 1","PROTEASE","RVP"],["4q1y","017","Darunavir (DB01264)","Human immunodeficiency virus 1","ASPARTYL PROTEASE","RVP"],["4rvj","478","Amprenavir (DB00701)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP"],["4yoa","017","Darunavir (DB01264)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP"],["5t2z","017","Darunavir (DB01264)","Human immunodeficiency virus 1","PROTEASE","NA"],["6bsg","EFZ","Efavirenz (DB00625)","Human immunodeficiency virus 1;synthetic construct","REVERSE TRANSCRIPTASE P66 SUBUNIT","RNase_H;RVT_1;RVT_connect;RVT_thumb"],["6dif","TPV","Tipranavir (DB00932)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP"],["6dj1","AB1","Lopinavir (DB01601)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP"],["6g9i","CXX","Clomipramine (DB01242)","Ebola virus - mayinga;zaire;1976;human immunodeficiency virus 1","ENVELOPE GLYCOPROTEIN","NA"],["6opv","017","Darunavir (DB01264)","Human immunodeficiency virus 1","PROTEASE NL4-3","RVP"],["6puw","KLQ","Bictegravir (DB11799)","Saccharolobus solfataricus (strain atcc 35092 \/ dsm 1617 \/ jcm 11322 \/ p2);human immunodeficiency virus 1;synthetic construct","CHIMERIC SSO7D AND HIV-1 INTEGRASE","7kD_DNA_binding;IN_DBD_C;Integrase_Zn;rve"],["6vdk","DLU","Dolutegravir (DB08930)","Human immunodeficiency virus 1;synthetic construct","INTEGRASE","IN_DBD_C;Integrase_Zn;rve"]]