Ligand ID: MK1

Drugbank ID:
Indinavir
(DB00224)

Indication:
Indinavir is a protease inhibitor used to treat HIV infection.

LIST OF BINDING INTERFACES for query 'MK1'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1C6Y_B_MK1B524	1c6y	MK1	Indinavir (DB00224)	Human immunodeficiency virus 1	PROTEIN (PROTEASE)	RVP	30	ARG A   8 LEU A  23 ASP A  25 GLY A  27 ALA A  28 ASP A  29 ASP A  30 VAL A  32 ILE A  47 GLY A  48 GLY A  49 ILE A  50 PRO A  81 THR A  82 ILE A  84 ASP B 225 GLY B 227 ALA B 228 ASP B 229 ASP B 230 VAL B 232 ILE B 247 GLY B 248 GLY B 249 ILE B 250 PRO B 279 THR B 280 PRO B 281 THR B 282 ILE B 284	MK1 B 524		Details
1HSH_A_MK1A401	1hsh	MK1	Indinavir (DB00224)	Human immunodeficiency virus 2	HIV-II PROTEASE	RVP	30	ARG B   8 ARG A   8 LEU B  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP A  29 ASP B  30 ASP A  30 SER A  31 ILE B  32 ILE A  32 VAL B  47 VAL A  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 MET A  76 PRO B  81 PRO A  81 ILE A  82 ILE B  82 ILE B  84 ILE A  84	MK1 A 401		Details
1SDV_B_MK1B902	1sdv	MK1	Indinavir (DB00224)	Human immunodeficiency virus 1	PROTEASE RETROPEPSIN	RVP	31	ARG A   8 LEU A  23 ASP A  25 GLY A  27 ALA A  28 ASP A  29 ASP A  30 VAL A  32 ILE A  47 GLY A  48 GLY A  49 ILE A  50 PHE A  53 PRO A  81 ALA A  82 ILE A  84 ARG B 108 LEU B 123 ASP B 125 GLY B 127 ALA B 128 ASP B 129 ASP B 130 VAL B 132 ILE B 147 GLY B 148 GLY B 149 ILE B 150 PRO B 181 ALA B 182 ILE B 184	MK1 B 902		Details
1SGU_B_MK1B2632	1sgu	MK1	Indinavir (DB00224)	Human immunodeficiency virus 1	POL POLYPROTEIN	RVP	29	ARG B   8 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 THR B  31 ILE B  32 ILE A  32 ILE A  47 ILE B  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 PRO B  81 PRO A  81 ALA A  82 ALA B  82 VAL B  84 VAL A  84	MK1 B2632		Details
2AVO_B_MK1B902	2avo	MK1	Indinavir (DB00224)	Human immunodeficiency virus 1	POL POLYPROTEIN	RVP	30	ARG B   8 ARG A   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 VAL B  32 VAL A  32 ILE A  47 ILE B  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 PRO B  81 PRO A  81 VAL B  82 VAL A  82 ILE B  84 ILE A  84	MK1 B 902		Details
2B7Z_B_MK1B200	2b7z	MK1	Indinavir (DB00224)	Human immunodeficiency virus 1	HIV-1 PROTEASE	RVP	29	ARG B   8 ARG A   8 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 ILE B  32 ILE A  32 ILE A  47 ILE B  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 PRO B  81 PRO A  81 ALA A  82 ALA B  82 VAL B  84 VAL A  84	MK1 B 200		Details
2R5P_B_MK1B902	2r5p	MK1	Indinavir (DB00224)	Human immunodeficiency virus 1	PROTEASE	RVP	31	ARG B   8 ARG A   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 VAL B  32 VAL A  32 ILE A  47 ILE B  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 PHE A  53 PRO B  81 PRO A  81 VAL B  82 VAL A  82 ILE B  84 ILE A  84	MK1 B 902		Details
3WSJ_A_MK1A201	3wsj	MK1	Indinavir (DB00224)	Human t-lymphotropic virus 1	PROTEASE	RVP	27	ARG A  10 ARG B  10 LEU B  30 LEU A  30 ASP A  32 ASP B  32 GLY B  34 GLY A  34 ALA A  35 ALA B  35 ASP A  36 ASP B  36 MET A  37 MET B  37 VAL B  39 VAL A  39 VAL B  56 LEU A  57 LEU B  57 ALA A  59 LEU B  91 LEU A  91 TRP A  98 TRP B  98 ALA A  99 ILE A 100 ILE B 100	MK1 A 201		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1C6Y_B_MK1B524","1c6y","MK1","Indinavir (DB00224)","Human immunodeficiency virus 1","PROTEIN (PROTEASE)","RVP",30,"ARG A 8;LEU A 23;ASP A 25;GLY A 27;ALA A 28;ASP A 29;ASP A 30;VAL A 32;ILE A 47;GLY A 48;GLY A 49;ILE A 50;PRO A 81;THR A 82;ILE A 84;ASP B 225;GLY B 227;ALA B 228;ASP B 229;ASP B 230;VAL B 232;ILE B 247;GLY B 248;GLY B 249;ILE B 250;PRO B 279;THR B 280;PRO B 281;THR B 282;ILE B 284","MK1 B 524\r"],["1HSH_A_MK1A401","1hsh","MK1","Indinavir (DB00224)","Human immunodeficiency virus 2","HIV-II PROTEASE","RVP",30,"ARG B 8;ARG A 8;LEU B 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP A 29;ASP B 30;ASP A 30;SER A 31;ILE B 32;ILE A 32;VAL B 47;VAL A 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;MET A 76;PRO B 81;PRO A 81;ILE A 82;ILE B 82;ILE B 84;ILE A 84","MK1 A 401\r"],["1SDV_B_MK1B902","1sdv","MK1","Indinavir (DB00224)","Human immunodeficiency virus 1","PROTEASE RETROPEPSIN","RVP",31,"ARG A 8;LEU A 23;ASP A 25;GLY A 27;ALA A 28;ASP A 29;ASP A 30;VAL A 32;ILE A 47;GLY A 48;GLY A 49;ILE A 50;PHE A 53;PRO A 81;ALA A 82;ILE A 84;ARG B 108;LEU B 123;ASP B 125;GLY B 127;ALA B 128;ASP B 129;ASP B 130;VAL B 132;ILE B 147;GLY B 148;GLY B 149;ILE B 150;PRO B 181;ALA B 182;ILE B 184","MK1 B 902\r"],["1SGU_B_MK1B2632","1sgu","MK1","Indinavir (DB00224)","Human immunodeficiency virus 1","POL POLYPROTEIN","RVP",29,"ARG B 8;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;THR B 31;ILE B 32;ILE A 32;ILE A 47;ILE B 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;PRO B 81;PRO A 81;ALA A 82;ALA B 82;VAL B 84;VAL A 84","MK1 B2632\r"],["2AVO_B_MK1B902","2avo","MK1","Indinavir (DB00224)","Human immunodeficiency virus 1","POL POLYPROTEIN","RVP",30,"ARG B 8;ARG A 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;VAL B 32;VAL A 32;ILE A 47;ILE B 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;PRO B 81;PRO A 81;VAL B 82;VAL A 82;ILE B 84;ILE A 84","MK1 B 902\r"],["2B7Z_B_MK1B200","2b7z","MK1","Indinavir (DB00224)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP",29,"ARG B 8;ARG A 8;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;ILE B 32;ILE A 32;ILE A 47;ILE B 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;PRO B 81;PRO A 81;ALA A 82;ALA B 82;VAL B 84;VAL A 84","MK1 B 200\r"],["2R5P_B_MK1B902","2r5p","MK1","Indinavir (DB00224)","Human immunodeficiency virus 1","PROTEASE","RVP",31,"ARG B 8;ARG A 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;VAL B 32;VAL A 32;ILE A 47;ILE B 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;PHE A 53;PRO B 81;PRO A 81;VAL B 82;VAL A 82;ILE B 84;ILE A 84","MK1 B 902\r"],["3WSJ_A_MK1A201","3wsj","MK1","Indinavir (DB00224)","Human t-lymphotropic virus 1","PROTEASE","RVP",27,"ARG A 10;ARG B 10;LEU B 30;LEU A 30;ASP A 32;ASP B 32;GLY B 34;GLY A 34;ALA A 35;ALA B 35;ASP A 36;ASP B 36;MET A 37;MET B 37;VAL B 39;VAL A 39;VAL B 56;LEU A 57;LEU B 57;ALA A 59;LEU B 91;LEU A 91;TRP A 98;TRP B 98;ALA A 99;ILE A 100;ILE B 100","MK1 A 201\r"]]