Ligand ID: 017

Drugbank ID:
Darunavir
(DB01264)

Indication:
Darunavir is a HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies.

LIST OF BINDING INTERFACES for query 'DB01264'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2HS1_A_017A201	2hs1	017	Darunavir (DB01264)	Human immunodeficiency virus 1	HIV-1 PROTEASE	RVP	30	ARG A   8 LEU A  23 ASP A  25 GLY A  27 ALA A  28 ASP A  29 ASP A  30 ILE A  32 ILE A  47 GLY A  48 GLY A  49 ILE A  50 PRO A  81 VAL A  82 ILE A  84 ARG B 108 LEU B 123 ASP B 125 GLY B 127 ALA B 128 ASP B 129 ASP B 130 ILE B 132 ILE B 147 GLY B 148 GLY B 149 ILE B 150 PRO B 181 VAL B 182 ILE B 184	017 A 201		Details
2IDW_B_017B401	2idw	017	Darunavir (DB01264)	Human immunodeficiency virus 1	PROTEASE	RVP	28	LEU A  23 ASP A  25 GLY A  27 ALA A  28 ASP A  29 ASP A  30 VAL A  32 ILE A  47 GLY A  48 GLY A  49 ILE A  50 LEU A  76 PRO A  81 ALA A  82 ILE A  84 LEU B 123 ASP B 125 GLY B 127 ALA B 128 ASP B 129 ASP B 130 VAL B 132 ILE B 147 GLY B 148 GLY B 149 ILE B 150 ALA B 182 ILE B 184	017 B 401		Details
3EBZ_B_017B201	3ebz	017	Darunavir (DB01264)	Human immunodeficiency virus type 2 (isolate rod)	PROTEASE	RVP	28	ARG A   8 LEU A  23 ASP A  25 GLY A  27 ALA A  28 ASP A  29 ASP A  30 ILE A  32 VAL A  47 GLY A  48 GLY A  49 ILE A  50 PRO A  81 ILE A  82 ILE A  84 LEU B 123 ASP B 125 GLY B 127 ALA B 128 ASP B 129 ASP B 130 ILE B 132 VAL B 147 GLY B 148 GLY B 149 ILE B 150 ILE B 182 ILE B 184	017 B 201		Details
3GGU_B_017B201	3ggu	017	Darunavir (DB01264)	Human immunodeficiency virus type 1 (bru isolate)	PROTEASE	RVP	29	ARG A   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 VAL B  32 VAL A  32 ILE A  47 ILE B  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 PRO B  81 PRO A  81 THR A  82 THR B  82 VAL B  84 VAL A  84	017 B 201		Details
3LZU_A_017A200	3lzu	017	Darunavir (DB01264)	Human immunodeficiency virus 1	HIV-1 PROTEASE	RVP	30	LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 VAL B  32 VAL A  32 ILE A  47 ILE B  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 LEU A  76 LEU B  76 PRO B  81 PRO A  81 VAL B  82 VAL A  82 ILE B  84 ILE A  84	017 A 200		Details
3MWS_B_017B201	3mws	017	Darunavir (DB01264)	Human immunodeficiency virus 1	HIV-1 PROTEASE	RVP	32	ARG A   8 LEU A  23 ASP A  25 GLY A  27 ALA A  28 ASP A  29 ASP A  30 VAL A  32 ILE A  47 GLY A  48 GLY A  49 ILE A  50 LEU A  76 PRO A  81 VAL A  82 ILE A  84 ARG B 108 LEU B 123 ASP B 125 GLY B 127 ALA B 128 ASP B 129 ASP B 130 VAL B 132 ILE B 147 GLY B 148 GLY B 149 ILE B 150 LEU B 176 PRO B 181 VAL B 182 ILE B 184	017 B 201		Details
3OGP_A_017A200	3ogp	017	Darunavir (DB01264)	Feline immunodeficiency virus	FIV PROTEASE	RVP	26	ARG B  13 LEU B  28 ASP B  30 ASP A  30 GLY A  32 GLY B  32 ALA A  33 ALA B  33 ASP A  34 ASP B  34 ILE B  35 ILE A  35 VAL B  37 VAL A  37 MET B  56 MET A  56 ILE A  57 ILE B  57 GLY B  58 GLY A  58 ILE B  59 ILE A  59 SER B  98 VAL B  99 LEU A 101 LEU B 101	017 A 200		Details
3T3C_A_017A201	3t3c	017	Darunavir (DB01264)	Human immunodeficiency virus type 1	HIV-1 PROTEASE	RVP	29	ARG A   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 VAL B  32 VAL A  32 ILE A  47 ILE B  47 ALA B  48 ALA A  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 LEU B  76 PRO B  81 ALA A  82 ALA B  82 VAL B  84 VAL A  84	017 A 201		Details
3TTP_A_017A201	3ttp	017	Darunavir (DB01264)	Human immunodeficiency virus type 1	HIV-1 PROTEASE	RVP	29	ARG A   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 ILE B  32 ILE A  32 VAL B  47 VAL A  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 PRO B  81 PRO A  81 LEU A  82 LEU B  82 ILE B  84 ILE A  84	017 A 201		Details
3U7S_A_017A201	3u7s	017	Darunavir (DB01264)	Human immunodeficiency virus 1	POL POLYPROTEIN	RVP	25	ARG B   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 ILE B  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 PRO B  81 LEU A  82 LEU B  82 VAL B  84 VAL A  84	017 A 201		Details
3U7S_A_017A202	3u7s	017	Darunavir (DB01264)	Human immunodeficiency virus 1	POL POLYPROTEIN	RVP	26	ARG A   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 ILE A  47 ILE B  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 PRO A  81 LEU A  82 LEU B  82 VAL B  84 VAL A  84	017 A 202		Details
3UCB_A_017A201	3ucb	017	Darunavir (DB01264)	Human immunodeficiency virus 1	PROTEASE	RVP	31	ARG B   8 ARG A   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASN B  30 ASN A  30 ILE B  32 ILE A  32 VAL B  47 VAL A  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 LEU B  76 PRO B  81 PRO A  81 VAL B  82 VAL A  82 VAL B  84 VAL A  84	017 A 201		Details
4NJT_B_017B101	4njt	017	Darunavir (DB01264)	Human immunodeficiency virus 1	PROTEASE	RVP	29	ARG B   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 VAL B  32 VAL A  32 ILE A  47 ILE B  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 LEU A  76 PRO A  81 THR A  82 THR B  82 ILE B  84 ILE A  84	017 B 101		Details
4NPT_A_017A401	4npt	017	Darunavir (DB01264)	Human immunodeficiency virus 1	PROTEASE	RVP	15	LEU A  23 ASN A  25 GLY A  27 ALA A  28 ILE A  32 ILE A  47 GLY A  48 GLY A  49 ILE A  50 GLY A  52 PHE A  53 MET A  54 THR A  80 ILE A  82 VAL A  84	017 A 401		Details
4Q1Y_A_017A106	4q1y	017	Darunavir (DB01264)	Human immunodeficiency virus 1	ASPARTYL PROTEASE	RVP	30	ARG B   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 ILE B  32 ILE A  32 ILE A  47 ILE B  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 LEU B  76 PRO B  81 PRO A  81 VAL B  82 VAL A  82 ILE B  84 ILE A  84	017 A 106		Details
4YOA_A_017A100	4yoa	017	Darunavir (DB01264)	Human immunodeficiency virus 1	HIV-1 PROTEASE	RVP	9	LEU A  23 ASN A  25 GLY A  27 ALA A  28 ASP A  29 THR A  80 PRO A  81 THR A  82 VAL A  84	017 A 100		Details
5T2Z_B_017B201	5t2z	017	Darunavir (DB01264)	Human immunodeficiency virus 1	PROTEASE	NA	30	LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 VAL B  32 VAL A  32 ILE A  47 ILE B  47 VAL B  48 VAL A  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 THR A  80 THR B  80 PRO B  81 PRO A  81 SER B  82 SER A  82 ILE B  84 ILE A  84	017 B 201		Details
6OPV_B_017B101	6opv	017	Darunavir (DB01264)	Human immunodeficiency virus 1	PROTEASE NL4-3	RVP	32	ARG B   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 THR B  31 ILE B  32 ILE A  32 ILE A  47 ILE B  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 LEU A  76 LEU B  76 PRO B  81 PRO A  81 PHE B  82 PHE A  82 VAL B  84 VAL A  84	017 B 101		Details
6P9A_A_017A101	6p9a	017	Darunavir (DB01264)	Human immunodeficiency virus type 1 group m subtype b (isolate bru/lai)	HIV-1 PROTEASE	RVP	28	LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 VAL B  32 VAL A  32 ILE A  47 ILE B  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 LEU B  76 PRO B  81 VAL B  82 VAL A  82 VAL B  84 VAL A  84	017 A 101		Details
6W6Q_B_017B201	6w6q	017	Darunavir (DB01264)	Human t-cell leukemia virus type i	HTLV-1 PROTEASE	RVP	30	ARG A  10 ARG B  10 LEU B  30 LEU A  30 ASP A  32 ASP B  32 GLY B  34 GLY A  34 ALA A  35 ALA B  35 ASP A  36 ASP B  36 MET A  37 MET B  37 VAL B  39 VAL A  39 VAL A  56 VAL B  56 LEU A  57 LEU B  57 GLY B  58 GLY A  58 ALA B  59 ALA A  59 LEU B  91 LEU A  91 TRP A  98 TRP B  98 ILE A 100 ILE B 100	017 B 201		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2HS1_A_017A201","2hs1","017","Darunavir (DB01264)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP",30,"ARG A 8;LEU A 23;ASP A 25;GLY A 27;ALA A 28;ASP A 29;ASP A 30;ILE A 32;ILE A 47;GLY A 48;GLY A 49;ILE A 50;PRO A 81;VAL A 82;ILE A 84;ARG B 108;LEU B 123;ASP B 125;GLY B 127;ALA B 128;ASP B 129;ASP B 130;ILE B 132;ILE B 147;GLY B 148;GLY B 149;ILE B 150;PRO B 181;VAL B 182;ILE B 184","017 A 201\r"],["2IDW_B_017B401","2idw","017","Darunavir (DB01264)","Human immunodeficiency virus 1","PROTEASE","RVP",28,"LEU A 23;ASP A 25;GLY A 27;ALA A 28;ASP A 29;ASP A 30;VAL A 32;ILE A 47;GLY A 48;GLY A 49;ILE A 50;LEU A 76;PRO A 81;ALA A 82;ILE A 84;LEU B 123;ASP B 125;GLY B 127;ALA B 128;ASP B 129;ASP B 130;VAL B 132;ILE B 147;GLY B 148;GLY B 149;ILE B 150;ALA B 182;ILE B 184","017 B 401\r"],["3EBZ_B_017B201","3ebz","017","Darunavir (DB01264)","Human immunodeficiency virus type 2 (isolate rod)","PROTEASE","RVP",28,"ARG A 8;LEU A 23;ASP A 25;GLY A 27;ALA A 28;ASP A 29;ASP A 30;ILE A 32;VAL A 47;GLY A 48;GLY A 49;ILE A 50;PRO A 81;ILE A 82;ILE A 84;LEU B 123;ASP B 125;GLY B 127;ALA B 128;ASP B 129;ASP B 130;ILE B 132;VAL B 147;GLY B 148;GLY B 149;ILE B 150;ILE B 182;ILE B 184","017 B 201\r"],["3GGU_B_017B201","3ggu","017","Darunavir (DB01264)","Human immunodeficiency virus type 1 (bru isolate)","PROTEASE","RVP",29,"ARG A 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;VAL B 32;VAL A 32;ILE A 47;ILE B 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;PRO B 81;PRO A 81;THR A 82;THR B 82;VAL B 84;VAL A 84","017 B 201\r"],["3LZU_A_017A200","3lzu","017","Darunavir (DB01264)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP",30,"LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;VAL B 32;VAL A 32;ILE A 47;ILE B 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;LEU A 76;LEU B 76;PRO B 81;PRO A 81;VAL B 82;VAL A 82;ILE B 84;ILE A 84","017 A 200\r"],["3MWS_B_017B201","3mws","017","Darunavir (DB01264)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP",32,"ARG A 8;LEU A 23;ASP A 25;GLY A 27;ALA A 28;ASP A 29;ASP A 30;VAL A 32;ILE A 47;GLY A 48;GLY A 49;ILE A 50;LEU A 76;PRO A 81;VAL A 82;ILE A 84;ARG B 108;LEU B 123;ASP B 125;GLY B 127;ALA B 128;ASP B 129;ASP B 130;VAL B 132;ILE B 147;GLY B 148;GLY B 149;ILE B 150;LEU B 176;PRO B 181;VAL B 182;ILE B 184","017 B 201\r"],["3OGP_A_017A200","3ogp","017","Darunavir (DB01264)","Feline immunodeficiency virus","FIV PROTEASE","RVP",26,"ARG B 13;LEU B 28;ASP B 30;ASP A 30;GLY A 32;GLY B 32;ALA A 33;ALA B 33;ASP A 34;ASP B 34;ILE B 35;ILE A 35;VAL B 37;VAL A 37;MET B 56;MET A 56;ILE A 57;ILE B 57;GLY B 58;GLY A 58;ILE B 59;ILE A 59;SER B 98;VAL B 99;LEU A 101;LEU B 101","017 A 200\r"],["3T3C_A_017A201","3t3c","017","Darunavir (DB01264)","Human immunodeficiency virus type 1","HIV-1 PROTEASE","RVP",29,"ARG A 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;VAL B 32;VAL A 32;ILE A 47;ILE B 47;ALA B 48;ALA A 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;LEU B 76;PRO B 81;ALA A 82;ALA B 82;VAL B 84;VAL A 84","017 A 201\r"],["3TTP_A_017A201","3ttp","017","Darunavir (DB01264)","Human immunodeficiency virus type 1","HIV-1 PROTEASE","RVP",29,"ARG A 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;ILE B 32;ILE A 32;VAL B 47;VAL A 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;PRO B 81;PRO A 81;LEU A 82;LEU B 82;ILE B 84;ILE A 84","017 A 201\r"],["3U7S_A_017A201","3u7s","017","Darunavir (DB01264)","Human immunodeficiency virus 1","POL POLYPROTEIN","RVP",25,"ARG B 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;ILE B 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;PRO B 81;LEU A 82;LEU B 82;VAL B 84;VAL A 84","017 A 201\r"],["3U7S_A_017A202","3u7s","017","Darunavir (DB01264)","Human immunodeficiency virus 1","POL POLYPROTEIN","RVP",26,"ARG A 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;ILE A 47;ILE B 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;PRO A 81;LEU A 82;LEU B 82;VAL B 84;VAL A 84","017 A 202\r"],["3UCB_A_017A201","3ucb","017","Darunavir (DB01264)","Human immunodeficiency virus 1","PROTEASE","RVP",31,"ARG B 8;ARG A 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASN B 30;ASN A 30;ILE B 32;ILE A 32;VAL B 47;VAL A 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;LEU B 76;PRO B 81;PRO A 81;VAL B 82;VAL A 82;VAL B 84;VAL A 84","017 A 201\r"],["4NJT_B_017B101","4njt","017","Darunavir (DB01264)","Human immunodeficiency virus 1","PROTEASE","RVP",29,"ARG B 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;VAL B 32;VAL A 32;ILE A 47;ILE B 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;LEU A 76;PRO A 81;THR A 82;THR B 82;ILE B 84;ILE A 84","017 B 101\r"],["4NPT_A_017A401","4npt","017","Darunavir (DB01264)","Human immunodeficiency virus 1","PROTEASE","RVP",15,"LEU A 23;ASN A 25;GLY A 27;ALA A 28;ILE A 32;ILE A 47;GLY A 48;GLY A 49;ILE A 50;GLY A 52;PHE A 53;MET A 54;THR A 80;ILE A 82;VAL A 84","017 A 401\r"],["4Q1Y_A_017A106","4q1y","017","Darunavir (DB01264)","Human immunodeficiency virus 1","ASPARTYL PROTEASE","RVP",30,"ARG B 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;ILE B 32;ILE A 32;ILE A 47;ILE B 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;LEU B 76;PRO B 81;PRO A 81;VAL B 82;VAL A 82;ILE B 84;ILE A 84","017 A 106\r"],["4YOA_A_017A100","4yoa","017","Darunavir (DB01264)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP",9,"LEU A 23;ASN A 25;GLY A 27;ALA A 28;ASP A 29;THR A 80;PRO A 81;THR A 82;VAL A 84","017 A 100\r"],["5T2Z_B_017B201","5t2z","017","Darunavir (DB01264)","Human immunodeficiency virus 1","PROTEASE","NA",30,"LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;VAL B 32;VAL A 32;ILE A 47;ILE B 47;VAL B 48;VAL A 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;THR A 80;THR B 80;PRO B 81;PRO A 81;SER B 82;SER A 82;ILE B 84;ILE A 84","017 B 201\r"],["6OPV_B_017B101","6opv","017","Darunavir (DB01264)","Human immunodeficiency virus 1","PROTEASE NL4-3","RVP",32,"ARG B 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;THR B 31;ILE B 32;ILE A 32;ILE A 47;ILE B 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;LEU A 76;LEU B 76;PRO B 81;PRO A 81;PHE B 82;PHE A 82;VAL B 84;VAL A 84","017 B 101\r"],["6P9A_A_017A101","6p9a","017","Darunavir (DB01264)","Human immunodeficiency virus type 1 group m subtype b (isolate bru\/lai)","HIV-1 PROTEASE","RVP",28,"LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;VAL B 32;VAL A 32;ILE A 47;ILE B 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;LEU B 76;PRO B 81;VAL B 82;VAL A 82;VAL B 84;VAL A 84","017 A 101\r"],["6W6Q_B_017B201","6w6q","017","Darunavir (DB01264)","Human t-cell leukemia virus type i","HTLV-1 PROTEASE","RVP",30,"ARG A 10;ARG B 10;LEU B 30;LEU A 30;ASP A 32;ASP B 32;GLY B 34;GLY A 34;ALA A 35;ALA B 35;ASP A 36;ASP B 36;MET A 37;MET B 37;VAL B 39;VAL A 39;VAL A 56;VAL B 56;LEU A 57;LEU B 57;GLY B 58;GLY A 58;ALA B 59;ALA A 59;LEU B 91;LEU A 91;TRP A 98;TRP B 98;ILE A 100;ILE B 100","017 B 201\r"]]