Ligand ID: AB1

Drugbank ID:
Lopinavir
(DB01601)

Indication:
Lopinavir is an HIV-1 protease inhibitor used in combination with ritonavir to treat human immunodeficiency virus (HIV) infection.

LIST OF BINDING INTERFACES for query 'DB01601'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2RKF_A_AB1A501	2rkf	AB1	Lopinavir (DB01601)	Human immunodeficiency virus 1	PROTEASE RETROPEPSIN	RVP	29	ARG A   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 ILE B  32 ILE A  32 VAL B  47 VAL A  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 PRO B  81 PRO A  81 ALA A  82 ALA B  82 ILE B  84 ILE A  84	AB1 A 501		Details
3OGQ_A_AB1A200	3ogq	AB1	Lopinavir (DB01601)	Feline immunodeficiency virus	FIV PROTEASE	RVP	30	ARG B  13 ARG A  13 LEU A  28 LEU B  28 ASP B  30 ASP A  30 GLY A  32 GLY B  32 ALA A  33 ALA B  33 ASP A  34 ASP B  34 ILE B  35 ILE A  35 VAL B  37 VAL A  37 MET B  56 MET A  56 ILE A  57 ILE B  57 GLY B  58 GLY A  58 ILE B  59 ILE A  59 SER A  98 SER B  98 VAL A  99 VAL B  99 LEU A 101 LEU B 101	AB1 A 200		Details
4L1A_A_AB1A101	4l1a	AB1	Lopinavir (DB01601)	Human immunodeficiency virus 1	MDR769 HIV-1 PROTEASE	RVP	21	ARG B   8 ARG A   8 LEU B  23 ASN A  25 ASN B  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 GLY B  48 ILE A  50 THR A  80 PRO B  81 PRO A  81 THR A  82 THR B  82 VAL A  84	AB1 A 101		Details
6DJ1_B_AB1B201	6dj1	AB1	Lopinavir (DB01601)	Human immunodeficiency virus 1	HIV-1 PROTEASE	RVP	30	ARG B   8 ARG A   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 VAL B  32 VAL A  32 ILE A  47 ILE B  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 PRO B  81 PRO A  81 VAL B  82 VAL A  82 ILE B  84 ILE A  84	AB1 B 201		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2RKF_A_AB1A501","2rkf","AB1","Lopinavir (DB01601)","Human immunodeficiency virus 1","PROTEASE RETROPEPSIN","RVP",29,"ARG A 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;ILE B 32;ILE A 32;VAL B 47;VAL A 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;PRO B 81;PRO A 81;ALA A 82;ALA B 82;ILE B 84;ILE A 84","AB1 A 501\r"],["3OGQ_A_AB1A200","3ogq","AB1","Lopinavir (DB01601)","Feline immunodeficiency virus","FIV PROTEASE","RVP",30,"ARG B 13;ARG A 13;LEU A 28;LEU B 28;ASP B 30;ASP A 30;GLY A 32;GLY B 32;ALA A 33;ALA B 33;ASP A 34;ASP B 34;ILE B 35;ILE A 35;VAL B 37;VAL A 37;MET B 56;MET A 56;ILE A 57;ILE B 57;GLY B 58;GLY A 58;ILE B 59;ILE A 59;SER A 98;SER B 98;VAL A 99;VAL B 99;LEU A 101;LEU B 101","AB1 A 200\r"],["4L1A_A_AB1A101","4l1a","AB1","Lopinavir (DB01601)","Human immunodeficiency virus 1","MDR769 HIV-1 PROTEASE","RVP",21,"ARG B 8;ARG A 8;LEU B 23;ASN A 25;ASN B 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;GLY B 48;ILE A 50;THR A 80;PRO B 81;PRO A 81;THR A 82;THR B 82;VAL A 84","AB1 A 101\r"],["6DJ1_B_AB1B201","6dj1","AB1","Lopinavir (DB01601)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP",30,"ARG B 8;ARG A 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;VAL B 32;VAL A 32;ILE A 47;ILE B 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;PRO B 81;PRO A 81;VAL B 82;VAL A 82;ILE B 84;ILE A 84","AB1 B 201\r"]]