Ligand ID: TPV

Drugbank ID:
Tipranavir
(DB00932)

Indication:
Tipranavir is a protease inhibitor used to treat HIV-1 resistant to more than 1 protease inhibitor.

LIST OF BINDING INTERFACES for query 'TPV'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3SPK_A_TPVA100	3spk	TPV	Tipranavir (DB00932)	Human immunodeficiency virus type 1	HIV-1 PROTEASE	RVP	25	ARG B   8 ARG A   8 LEU B  23 LEU A  23 ASN A  25 ASN B  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP A  29 ASP A  30 VAL A  32 ILE A  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 PRO A  81 THR A  82 THR B  82 VAL B  84 VAL A  84	TPV A 100		Details
4NJU_A_TPVA500	4nju	TPV	Tipranavir (DB00932)	Human immunodeficiency virus 1	PROTEASE	RVP	27	ARG B   8 ARG A   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP A  29 ASP A  30 VAL B  32 VAL A  32 ILE A  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 PRO B  81 PRO A  81 THR A  82 THR B  82 ILE B  84 ILE A  84	TPV A 500		Details
6DIF_B_TPVB201	6dif	TPV	Tipranavir (DB00932)	Human immunodeficiency virus 1	HIV-1 PROTEASE	RVP	30	ARG B   8 ARG A   8 LEU B  23 LEU A  23 ASP B  25 ASP A  25 GLY A  27 GLY B  27 ALA B  28 ALA A  28 ASP B  29 ASP A  29 ASP B  30 ASP A  30 VAL B  32 VAL A  32 ILE A  47 ILE B  47 GLY A  48 GLY B  48 GLY A  49 GLY B  49 ILE B  50 ILE A  50 PRO B  81 PRO A  81 VAL B  82 VAL A  82 ILE B  84 ILE A  84	TPV B 201		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3SPK_A_TPVA100","3spk","TPV","Tipranavir (DB00932)","Human immunodeficiency virus type 1","HIV-1 PROTEASE","RVP",25,"ARG B 8;ARG A 8;LEU B 23;LEU A 23;ASN A 25;ASN B 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP A 29;ASP A 30;VAL A 32;ILE A 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;PRO A 81;THR A 82;THR B 82;VAL B 84;VAL A 84","TPV A 100\r"],["4NJU_A_TPVA500","4nju","TPV","Tipranavir (DB00932)","Human immunodeficiency virus 1","PROTEASE","RVP",27,"ARG B 8;ARG A 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP A 29;ASP A 30;VAL B 32;VAL A 32;ILE A 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;PRO B 81;PRO A 81;THR A 82;THR B 82;ILE B 84;ILE A 84","TPV A 500\r"],["6DIF_B_TPVB201","6dif","TPV","Tipranavir (DB00932)","Human immunodeficiency virus 1","HIV-1 PROTEASE","RVP",30,"ARG B 8;ARG A 8;LEU B 23;LEU A 23;ASP B 25;ASP A 25;GLY A 27;GLY B 27;ALA B 28;ALA A 28;ASP B 29;ASP A 29;ASP B 30;ASP A 30;VAL B 32;VAL A 32;ILE A 47;ILE B 47;GLY A 48;GLY B 48;GLY A 49;GLY B 49;ILE B 50;ILE A 50;PRO B 81;PRO A 81;VAL B 82;VAL A 82;ILE B 84;ILE A 84","TPV B 201\r"]]