LIST OF BINDING INTERFACES for query 'POLY [ADP-RIBOSE] POLYMERASE 1' in category 'PROTEIN NAME'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details
5ds3	09L	Olaparib (DB09074)	Olaparib is a chemotherapeutic agent used to treat recurrent or advanced ovarian cancer and metastatic breast cancer in patients with specific mutations and prior history of chemotherapy.	POLY [ADP-RIBOSE] POLYMERASE 1 (Homo sapiens)	PARP	5DS3_A_09LA1102	Details
5ha9	TP0	Amitriptyline (DB00321)	Amitriptyline is a tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.	POLY [ADP-RIBOSE] POLYMERASE 1 (Homo sapiens)	PARP PARP_reg	5HA9_B_TP0B406	Details
6vkk	RPB	Rucaparib (DB12332)	Rucaparib is an anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer.	POLY [ADP-RIBOSE] POLYMERASE 1 (Homo sapiens)	PARP PARP_reg	6VKK_A_RPBA1101	Details
7kk3	2YQ	Talazoparib (DB11760)	Talazoparib is a poly-ADP ribose polymerase inhibitor used to treat HER2-, BRCA mutated locally advanced or metastatic breast cancer.	POLY [ADP-RIBOSE] POLYMERASE 1 (Homo sapiens)	PARP PARP_reg	7KK3_A_2YQA9001	Details
7kk4	09L	Olaparib (DB09074)	Olaparib is a chemotherapeutic agent used to treat recurrent or advanced ovarian cancer and metastatic breast cancer in patients with specific mutations and prior history of chemotherapy.	POLY [ADP-RIBOSE] POLYMERASE 1 (Homo sapiens)	PARP PARP_reg	7KK4_A_09LA9001	Details
7kk5	3JD	Niraparib (DB11793)	Niraparib is a poly-ADP ribose polymerase inhibitor used to treat recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer responding to platinum based chemotherapy.	POLY [ADP-RIBOSE] POLYMERASE 1 (Homo sapiens)	PARP PARP_reg	7KK5_A_3JDA9001	Details
PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details

[["5ds3","09L","Olaparib (DB09074)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP"],["5ha9","TP0","Amitriptyline (DB00321)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP;PARP_reg"],["6vkk","RPB","Rucaparib (DB12332)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP;PARP_reg"],["7kk3","2YQ","Talazoparib (DB11760)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP;PARP_reg"],["7kk4","09L","Olaparib (DB09074)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP;PARP_reg"],["7kk5","3JD","Niraparib (DB11793)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP;PARP_reg"]]