Ligand ID: TP0

Drugbank ID:
Amitriptyline
(DB00321)

Indication:
Amitriptyline is a tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.

LIST OF BINDING INTERFACES for query 'TP0'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3APV_A_TP0A190	3apv	TP0	Amitriptyline (DB00321)	Homo sapiens	ALPHA-1-ACID GLYCOPROTEIN 2	Lipocalin	19	PHE A  32 TYR A  37 VAL A  41 PHE A  49 PHE A  51 LEU A  62 GLU A  64 LEU A  79 VAL A  88 SER A  89 ARG A  90 GLU A  92 HIS A  97 VAL A  98 ALA A  99 PHE A 112 SER A 114 SER A 125 TYR A 127	TP0 A 190		Details
5HA9_B_TP0B406	5ha9	TP0	Amitriptyline (DB00321)	Homo sapiens	POLY [ADP-RIBOSE] POLYMERASE 1	PARP PARP_reg	13	GLU B 102 ASP B 109 HIS B 201 GLY B 202 SER B 203 ASN B 207 ILE B 211 LEU B 216 ARG B 217 TYR B 235 PHE B 236 SER B 243 TYR B 246	TP0 B 406		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3APV_A_TP0A190","3apv","TP0","Amitriptyline (DB00321)","Homo sapiens","ALPHA-1-ACID GLYCOPROTEIN 2","Lipocalin",19,"PHE A 32;TYR A 37;VAL A 41;PHE A 49;PHE A 51;LEU A 62;GLU A 64;LEU A 79;VAL A 88;SER A 89;ARG A 90;GLU A 92;HIS A 97;VAL A 98;ALA A 99;PHE A 112;SER A 114;SER A 125;TYR A 127","TP0 A 190\r"],["5HA9_B_TP0B406","5ha9","TP0","Amitriptyline (DB00321)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP;PARP_reg",13,"GLU B 102;ASP B 109;HIS B 201;GLY B 202;SER B 203;ASN B 207;ILE B 211;LEU B 216;ARG B 217;TYR B 235;PHE B 236;SER B 243;TYR B 246","TP0 B 406\r"]]