Ligand ID: RPB

Drugbank ID:
Rucaparib
(DB12332)

Indication:
Rucaparib is an anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer.

LIST OF BINDING INTERFACES for query 'RPB'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
4BJC_A_RPBA2162	4bjc	RPB	Rucaparib (DB12332)	Homo sapiens	TANKYRASE-2	PARP	12	PHE A1030 HIS A1031 GLY A1032 ALA A1057 TYR A1060 PHE A1061 ALA A1062 LYS A1067 SER A1068 TYR A1071 ILE A1075 GLU A1138	RPB A2162		Details
6VKK_A_RPBA1101	6vkk	RPB	Rucaparib (DB12332)	Homo sapiens	POLY [ADP-RIBOSE] POLYMERASE 1	PARP PARP_reg	17	GLN A 759 GLU A 763 ASP A 766 TRP A 861 HIS A 862 GLY A 863 THR A 887 GLY A 888 TYR A 889 TYR A 896 PHE A 897 ALA A 898 LYS A 903 SER A 904 TYR A 907 ASN A 987 GLU A 988	RPB A1101		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["4BJC_A_RPBA2162","4bjc","RPB","Rucaparib (DB12332)","Homo sapiens","TANKYRASE-2","PARP",12,"PHE A1030;HIS A1031;GLY A1032;ALA A1057;TYR A1060;PHE A1061;ALA A1062;LYS A1067;SER A1068;TYR A1071;ILE A1075;GLU A1138","RPB A2162\r"],["6VKK_A_RPBA1101","6vkk","RPB","Rucaparib (DB12332)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP;PARP_reg",17,"GLN A 759;GLU A 763;ASP A 766;TRP A 861;HIS A 862;GLY A 863;THR A 887;GLY A 888;TYR A 889;TYR A 896;PHE A 897;ALA A 898;LYS A 903;SER A 904;TYR A 907;ASN A 987;GLU A 988","RPB A1101\r"]]