Ligand ID: 3JD

Drugbank ID:
Niraparib
(DB11793)

Indication:
Niraparib is a poly-ADP ribose polymerase inhibitor used to treat recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer responding to platinum based chemotherapy.

LIST OF BINDING INTERFACES for query '3JD'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
7KK5_A_3JDA9001	7kk5	3JD	Niraparib (DB11793)	Homo sapiens	POLY [ADP-RIBOSE] POLYMERASE 1	PARP PARP_reg	16	GLN A 759 VAL A 762 GLU A 763 ASP A 766 TRP A 861 HIS A 862 GLY A 863 GLY A 888 TYR A 889 TYR A 896 PHE A 897 ALA A 898 LYS A 903 SER A 904 TYR A 907 GLU A 988	3JD A9001		Details
7KKP_A_3JDA1402	7kkp	3JD	Niraparib (DB11793)	Homo sapiens	POLY [ADP-RIBOSE] POLYMERASE	PARP	12	PHE A1183 HIS A1184 GLY A1185 GLY A1206 TYR A1213 PHE A1214 ALA A1215 LYS A1220 SER A1221 TYR A1224 ILE A1228 GLU A1291	3JD A1402		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["7KK5_A_3JDA9001","7kk5","3JD","Niraparib (DB11793)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP;PARP_reg",16,"GLN A 759;VAL A 762;GLU A 763;ASP A 766;TRP A 861;HIS A 862;GLY A 863;GLY A 888;TYR A 889;TYR A 896;PHE A 897;ALA A 898;LYS A 903;SER A 904;TYR A 907;GLU A 988","3JD A9001\r"],["7KKP_A_3JDA1402","7kkp","3JD","Niraparib (DB11793)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE","PARP",12,"PHE A1183;HIS A1184;GLY A1185;GLY A1206;TYR A1213;PHE A1214;ALA A1215;LYS A1220;SER A1221;TYR A1224;ILE A1228;GLU A1291","3JD A1402\r"]]