LIST OF BINDING INTERFACES for query 'POLY [ADP-RIBOSE] POLYMERASE' in category 'PROTEIN NAME'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details
4pjv	2YQ	Talazoparib (DB11760)	Talazoparib is a poly-ADP ribose polymerase inhibitor used to treat HER2-, BRCA mutated locally advanced or metastatic breast cancer.	POLY [ADP-RIBOSE] POLYMERASE 2 (Homo sapiens)	PARP	4PJV_A_2YQA601	Details
4tvj	09L	Olaparib (DB09074)	Olaparib is a chemotherapeutic agent used to treat recurrent or advanced ovarian cancer and metastatic breast cancer in patients with specific mutations and prior history of chemotherapy.	POLY [ADP-RIBOSE] POLYMERASE 2 (Homo sapiens)	PARP	4TVJ_A_09LA601	Details
5ds3	09L	Olaparib (DB09074)	Olaparib is a chemotherapeutic agent used to treat recurrent or advanced ovarian cancer and metastatic breast cancer in patients with specific mutations and prior history of chemotherapy.	POLY [ADP-RIBOSE] POLYMERASE 1 (Homo sapiens)	PARP	5DS3_A_09LA1102	Details
5ha9	TP0	Amitriptyline (DB00321)	Amitriptyline is a tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety.	POLY [ADP-RIBOSE] POLYMERASE 1 (Homo sapiens)	PARP PARP_reg	5HA9_B_TP0B406	Details
6vkk	RPB	Rucaparib (DB12332)	Rucaparib is an anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer.	POLY [ADP-RIBOSE] POLYMERASE 1 (Homo sapiens)	PARP PARP_reg	6VKK_A_RPBA1101	Details
7kk3	2YQ	Talazoparib (DB11760)	Talazoparib is a poly-ADP ribose polymerase inhibitor used to treat HER2-, BRCA mutated locally advanced or metastatic breast cancer.	POLY [ADP-RIBOSE] POLYMERASE 1 (Homo sapiens)	PARP PARP_reg	7KK3_A_2YQA9001	Details
7kk4	09L	Olaparib (DB09074)	Olaparib is a chemotherapeutic agent used to treat recurrent or advanced ovarian cancer and metastatic breast cancer in patients with specific mutations and prior history of chemotherapy.	POLY [ADP-RIBOSE] POLYMERASE 1 (Homo sapiens)	PARP PARP_reg	7KK4_A_09LA9001	Details
7kk5	3JD	Niraparib (DB11793)	Niraparib is a poly-ADP ribose polymerase inhibitor used to treat recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer responding to platinum based chemotherapy.	POLY [ADP-RIBOSE] POLYMERASE 1 (Homo sapiens)	PARP PARP_reg	7KK5_A_3JDA9001	Details
7kkn	2YQ	Talazoparib (DB11760)	Talazoparib is a poly-ADP ribose polymerase inhibitor used to treat HER2-, BRCA mutated locally advanced or metastatic breast cancer.	POLY [ADP-RIBOSE] POLYMERASE (Homo sapiens)	PARP	7KKN_A_2YQA9002	Details
7kko	09L	Olaparib (DB09074)	Olaparib is a chemotherapeutic agent used to treat recurrent or advanced ovarian cancer and metastatic breast cancer in patients with specific mutations and prior history of chemotherapy.	POLY [ADP-RIBOSE] POLYMERASE (Homo sapiens)	PARP	7KKO_A_09LA1402	Details
7kkp	3JD	Niraparib (DB11793)	Niraparib is a poly-ADP ribose polymerase inhibitor used to treat recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer responding to platinum based chemotherapy.	POLY [ADP-RIBOSE] POLYMERASE (Homo sapiens)	PARP	7KKP_A_3JDA1402	Details
PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details

[["4pjv","2YQ","Talazoparib (DB11760)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 2","PARP"],["4tvj","09L","Olaparib (DB09074)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 2","PARP"],["5ds3","09L","Olaparib (DB09074)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP"],["5ha9","TP0","Amitriptyline (DB00321)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP;PARP_reg"],["6vkk","RPB","Rucaparib (DB12332)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP;PARP_reg"],["7kk3","2YQ","Talazoparib (DB11760)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP;PARP_reg"],["7kk4","09L","Olaparib (DB09074)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP;PARP_reg"],["7kk5","3JD","Niraparib (DB11793)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE 1","PARP;PARP_reg"],["7kkn","2YQ","Talazoparib (DB11760)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE","PARP"],["7kko","09L","Olaparib (DB09074)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE","PARP"],["7kkp","3JD","Niraparib (DB11793)","Homo sapiens","POLY [ADP-RIBOSE] POLYMERASE","PARP"]]