LIST OF BINDING INTERFACES for query 'MITOGEN-ACTIVATED PROTEIN KINASE 1' in category 'PROTEIN NAME'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details
3gcs	BAX	Sorafenib (DB00398)	Sorafenib is a kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma.	MITOGEN-ACTIVATED PROTEIN KINASE 14 (Homo sapiens)	Pkinase	3GCS_A_BAXA401	Details
3gp0	NIL	Nilotinib (DB04868)	Nilotinib is a kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib.	MITOGEN-ACTIVATED PROTEIN KINASE 11 (Homo sapiens)	Pkinase	3GP0_A_NILA1	Details
3hec	STI	Imatinib (DB00619)	Imatinib is a tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.	MITOGEN-ACTIVATED PROTEIN KINASE 14 (Homo sapiens)	Pkinase	3HEC_A_STIA1	Details
3lfa	1N1	Dasatinib (DB01254)	Dasatinib is a tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy.	MITOGEN-ACTIVATED PROTEIN KINASE 14 (Homo sapiens)	Pkinase	3LFA_A_1N1A361	Details
4xp3	DX4	Tioguanine (DB00352)	Tioguanine is a purine analogue antineoplastic agent used for the induction of remission, and for remission consolidation in patients with acute nonlymphocytic anemias.	MITOGEN-ACTIVATED PROTEIN KINASE 1 (Rattus norvegicus)	Pkinase	4XP3_A_DX4A401	Details
5r9p	SFY	Sulfapyridine (DB00891)	Sulfapyridine is a sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum.	MITOGEN-ACTIVATED PROTEIN KINASE 14 (Mus musculus)	Pkinase	5R9P_A_SFYA401	Details
6y82	308	Amantadine (DB00915)	Amantadine is a medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications.	MITOGEN-ACTIVATED PROTEIN KINASE 14 (Mus musculus)	Pkinase	6Y82_A_308A406	Details
PDB	Ligand	Drug	Indication	Macromolecule/ Organism	Pfam	Binding_Interfaces (View)	Details

[["3gcs","BAX","Sorafenib (DB00398)","Homo sapiens","MITOGEN-ACTIVATED PROTEIN KINASE 14","Pkinase"],["3gp0","NIL","Nilotinib (DB04868)","Homo sapiens","MITOGEN-ACTIVATED PROTEIN KINASE 11","Pkinase"],["3hec","STI","Imatinib (DB00619)","Homo sapiens","MITOGEN-ACTIVATED PROTEIN KINASE 14","Pkinase"],["3lfa","1N1","Dasatinib (DB01254)","Homo sapiens","MITOGEN-ACTIVATED PROTEIN KINASE 14","Pkinase"],["4xp3","DX4","Tioguanine (DB00352)","Rattus norvegicus","MITOGEN-ACTIVATED PROTEIN KINASE 1","Pkinase"],["5r9p","SFY","Sulfapyridine (DB00891)","Mus musculus","MITOGEN-ACTIVATED PROTEIN KINASE 14","Pkinase"],["6y82","308","Amantadine (DB00915)","Mus musculus","MITOGEN-ACTIVATED PROTEIN KINASE 14","Pkinase"]]