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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 2j0d | ERY | Erythromycin (DB00199) | Erythromycin is a macrolide antibiotic used to treat and prevent a variety of bacterial infections. | CYTOCHROME P450 3A4 (Homo sapiens) | p450 | ||
| 3nxu | RIT | Ritonavir (DB00503) | Ritonavir is an HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. | CYTOCHROME P450 3A4 (Homo sapiens) | p450 | ||
| 3ua1 | 08Y | Bromocriptine (DB01200) | Bromocriptine is a dopamine D2 receptor agonist used for the treatment of galactorrhea due to hyperprolactinemia and other prolactin-related conditions, as well as in early Parkinsonian Syndrome. | CYTOCHROME P450 3A4 (Homo sapiens) | p450 | ||
| 5a1r | STR | Progesterone (DB00396) | Progesterone is a hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia. | CYTOCHROME P450 3A4 (Homo sapiens) | p450 | ||
| 5g5j | MF8 | Metformin (DB00331) | Metformin is a biguanide drug used in conjunction with diet and exercise for glycemic control in type 2 diabetes mellitus and used off-label for insulin resistance in polycystic ovary syndrome (PCOS). | CYTOCHROME P450 3A4 (Homo sapiens) | p450 | ||
| 5te8 | 08J | Midazolam (DB00683) | Midazolam is a short-acting injectable benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders. | CYTOCHROME P450 3A4 (Homo sapiens) | p450 | ||
| 6ma6 | MYT | Metyrapone (DB01011) | Metyrapone is a steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function. | CYTOCHROME P450 3A4 (Homo sapiens) | p450 | ||
| 6ma7 | TPF | Fluconazole (DB00196) | Fluconazole is a triazole antifungal used to treat various fungal infections including candidiasis. | CYTOCHROME P450 3A4 (Homo sapiens) | p450 | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |