Ligand ID: MYT

Drugbank ID:
Metyrapone
(DB01011)

Indication:
Metyrapone is a steroid 11-beta-monooxygenase inhibitor used to test hypothalamic-pituitary ACTH function.

LIST OF BINDING INTERFACES for query 'MYT'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1PHG_A_MYTA422	1phg	MYT	Metyrapone (DB01011)	Pseudomonas putida	CYTOCHROME P450-CAM	p450	13	PHE A  87 TYR A  96 PHE A  98 THR A 185 LEU A 244 VAL A 247 GLY A 248 THR A 252 VAL A 295 ASP A 297 CYS A 357 ILE A 395 VAL A 396	MYT A 422		Details
4ZF8_A_MYTA502	4zf8	MYT	Metyrapone (DB01011)	Bacillus megaterium	BIFUNCTIONAL P-450/NADPH-P450 REDUCTASE	p450	9	VAL A  78 VAL A  87 LEU A 181 ILE A 263 ALA A 264 THR A 268 ALA A 328 LEU A 437 THR A 438	MYT A 502		Details
6MA6_A_MYTA603	6ma6	MYT	Metyrapone (DB01011)	Homo sapiens	CYTOCHROME P450 3A4	p450	9	ARG A 105 SER A 119 ARG A 212 ILE A 301 PHE A 304 ALA A 305 THR A 309 ALA A 370 ARG A 372	MYT A 603		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1PHG_A_MYTA422","1phg","MYT","Metyrapone (DB01011)","Pseudomonas putida","CYTOCHROME P450-CAM","p450",13,"PHE A 87;TYR A 96;PHE A 98;THR A 185;LEU A 244;VAL A 247;GLY A 248;THR A 252;VAL A 295;ASP A 297;CYS A 357;ILE A 395;VAL A 396","MYT A 422\r"],["4ZF8_A_MYTA502","4zf8","MYT","Metyrapone (DB01011)","Bacillus megaterium","BIFUNCTIONAL P-450\/NADPH-P450 REDUCTASE","p450",9,"VAL A 78;VAL A 87;LEU A 181;ILE A 263;ALA A 264;THR A 268;ALA A 328;LEU A 437;THR A 438","MYT A 502\r"],["6MA6_A_MYTA603","6ma6","MYT","Metyrapone (DB01011)","Homo sapiens","CYTOCHROME P450 3A4","p450",9,"ARG A 105;SER A 119;ARG A 212;ILE A 301;PHE A 304;ALA A 305;THR A 309;ALA A 370;ARG A 372","MYT A 603\r"]]