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| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
|---|---|---|---|---|---|---|---|
| 1am6 | HAE | Acetohydroxamic acid (DB00551) | Acetohydroxamic acid is a synthetic urea derivative used to treat urea splitting bacterial infections of the urinary tract. | CARBONIC ANHYDRASE (Homo sapiens) | Carb_anhydrase | ||
| 1avn | HSM | Histamine (DB05381) | Histamine is an ingredient of topical drugs for the relief of joint pain or muscle aches and pains. | CARBONIC ANHYDRASE II (Homo sapiens) | Carb_anhydrase | ||
| 1azm | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE I (Homo sapiens) | Carb_anhydrase | ||
| 1bzm | MZM | Methazolamide (DB00703) | Methazolamide is a carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma. | CARBONIC ANHYDRASE I (Homo sapiens) | Carb_anhydrase | ||
| 1cil | ETS | Dorzolamide (DB00869) | Dorzolamide is a carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma. | CARBONIC ANHYDRASE II (Homo sapiens) | Carb_anhydrase | ||
| 1dmy | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | MURINE CARBONIC ANHYDRASE V (Mus musculus) | NA | ||
| 1jd0 | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE XII (Homo sapiens) | Carb_anhydrase | ||
| 1oq5 | CEL | Celecoxib (DB00482) | Celecoxib is an NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. | CARBONIC ANHYDRASE II (Homo sapiens) | Carb_anhydrase | ||
| 1rj6 | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE XIV (Mus musculus) | Carb_anhydrase | ||
| 2aw1 | COX | Valdecoxib (DB00580) | Valdecoxib is a COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea. | CARBONIC ANHYDRASE II (Homo sapiens) | Carb_anhydrase | ||
| 2geh | NHY | Hydroxyurea (DB01005) | Hydroxyurea is an antimetabolite used to treat sickle cell anemia crisis. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 2hkk | ALE | Epinephrine (DB00668) | Epinephrine is a hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 2it4 | PPF | Foscarnet (DB00529) | Foscarnet is an antiviral used to treat CMV, HIV, and HSV infections. | CARBONIC ANHYDRASE 1 (Homo sapiens) | Carb_anhydrase | ||
| 2pou | I7A | Diclofenamide (DB01144) | Diclofenamide is a carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 3czv | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE 13 (Homo sapiens) | Carb_anhydrase | ||
| 3fw3 | ETS | Dorzolamide (DB00869) | Dorzolamide is a carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma. | CARBONIC ANHYDRASE 4 (Homo sapiens) | NA | ||
| 3hku | TOR | Topiramate (DB00273) | Topiramate is an anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 3hs4 | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 3iai | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE 9 (Homo sapiens) | NA | ||
| 3ieo | AMJ | Lacosamide (DB06218) | Lacosamide is an antiepileptic drug used to treat partial onset seizures in adults. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 3lxe | TOR | Topiramate (DB00273) | Topiramate is an anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines. | CARBONIC ANHYDRASE 1 (Homo sapiens) | Carb_anhydrase | ||
| 3ml5 | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE 7 (Homo sapiens) | Carb_anhydrase | ||
| 3ucj | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE (Coccomyxa sp. pa) | Pro_CA | ||
| 3znc | BZ1 | Brinzolamide (DB01194) | Brinzolamide is a carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. | CARBONIC ANHYDRASE IV (Mus musculus) | Carb_anhydrase | ||
| 4e3h | HQE | Hydroquinone (DB09526) | Hydroquinone is a topical brightening agent used for the treatment of skin disorders associated with hyperpigmentation including melasma, post-inflammatory hyperpigmentation, sunspots, and freckles. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 4e49 | RCO | Resorcinol (DB11085) | Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders... | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 4lu3 | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE 14 (Homo sapiens) | Carb_anhydrase | ||
| 4m2v | BZ1 | Brinzolamide (DB01194) | Brinzolamide is a carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 4n16 | CHD | Cholic acid (DB02659) | Cholic Acid is a bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 4x5s | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (Sulfurihydrogenibium azorense) | Carb_anhydrase | ||
| 4xiw | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE, ALPHA TYPE (Chlamydomonas reinhardtii) | Carb_anhydrase | ||
| 4ygf | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | ALPHA-CARBONIC ANHYDRASE (Helicobacter pylori) | Carb_anhydrase | ||
| 4yha | MZM | Methazolamide (DB00703) | Methazolamide is a carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma. | ALPHA-CARBONIC ANHYDRASE (Helicobacter pylori) | Carb_anhydrase | ||
| 5c8i | MZM | Methazolamide (DB00703) | Methazolamide is a carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 5jn8 | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE 4 (Homo sapiens) | NA | ||
| 5jna | TOR | Topiramate (DB00273) | Topiramate is an anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines. | CARBONIC ANHYDRASE 4 (Homo sapiens) | NA | ||
| 5jnc | 6LH | Mafenide (DB06795) | Mafenide is an antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds. | CARBONIC ANHYDRASE 4 (Homo sapiens) | NA | ||
| 5ku6 | MZM | Methazolamide (DB00703) | Methazolamide is a carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma. | CARBONIC ANHYDRASE 4 (Homo sapiens) | NA | ||
| 5m78 | SAL | Salicylic acid (DB00936) | Salicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 6g3q | FO9 | Famotidine (DB00927) | Famotidine is a histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 6g3v | FO9 | Famotidine (DB00927) | Famotidine is a histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome. | CARBONIC ANHYDRASE 1 (Homo sapiens) | Carb_anhydrase | ||
| 6im3 | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (Persephonella marina (strain dsm 14350 / ex-h1)) | Carb_anhydrase | ||
| 6rl9 | SAN | Sulfanilamide (DB00259) | Sulfanilamide is a sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 6sg0 | FUN | Furosemide (DB00695) | Furosemide is a loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 7bi5 | 010 | Benzyl alcohol (DB06770) | Benzyl alcohol is an antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older. | CARBONIC ANHYDRASE 2 (Homo sapiens) | Carb_anhydrase | ||
| 7coj | AZM | Acetazolamide (DB00819) | Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. | CARBONIC ANHYDRASE (Neosartorya fumigata (strain atcc mya-4609 / af293 / cbs 101355 / fgsc a1100)) | Pro_CA | ||
| PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |