Results: Ligand

Ligand ID: FUN

Drugbank ID:
Furosemide
(DB00695)

Indication:
Furosemide is a loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension.

LIST OF BINDING INTERFACES for query 'FUN'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
2XN5_A_FUNA1356	2xn5	FUN	Furosemide (DB00695)	Homo sapiens	THYROXINE-BINDING GLOBULIN	NA	16	SER A 23 SER A 24 ALA A 27 GLN A 238 LEU A 246 LEU A 248 SER A 266 LEU A 269 LYS A 270 TRP A 272 ASN A 273 LEU A 276 LEU B 376 ARG B 378 ARG B 381 ILE B 383	FUN A1356
3RF4_A_FUNA201	3rf4	FUN	Furosemide (DB00695)	Ancylostoma ceylanicum	MACROPHAGE MIGRATION INHIBITORY FACTOR	MIF	14	PRO A 1 MET A 2 LYS A 32 ASN A 35 ARG A 36 ILE A 37 ALA A 38 HIS C 49 SER A 63 ILE A 64 ILE C 95 VAL A 106 PHE A 108 VAL A 113	FUN A 201
6DE9_A_FUNA202	6de9	FUN	Furosemide (DB00695)	Homo sapiens	CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1	zf-CDGSH	6	LYS A 68 VAL A 70 CYS A 83 HIS A 87 PRO A 100 ILE A 102	FUN A 202
6SG0_A_FUNA306	6sg0	FUN	Furosemide (DB00695)	Homo sapiens	CARBONIC ANHYDRASE 2	Carb_anhydrase	21	ASN A 62 HIS A 64 ASN A 67 GLN A 92 HIS A 94 HIS A 96 GLU A 106 HIS A 119 VAL A 121 PHE A 131 VAL A 135 LEU A 141 VAL A 143 SER A 197 LEU A 198 THR A 199 THR A 200 PRO A 202 LEU A 204 VAL A 207 TRP A 209	FUN A 306
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["2XN5_A_FUNA1356","2xn5","FUN","Furosemide (DB00695)","Homo sapiens","THYROXINE-BINDING GLOBULIN","NA",16,"SER A  23;SER A  24;ALA A  27;GLN A 238;LEU A 246;LEU A 248;SER A 266;LEU A 269;LYS A 270;TRP A 272;ASN A 273;LEU A 276;LEU B 376;ARG B 378;ARG B 381;ILE B 383","FUN A1356\r"],["3RF4_A_FUNA201","3rf4","FUN","Furosemide (DB00695)","Ancylostoma ceylanicum","MACROPHAGE MIGRATION INHIBITORY FACTOR","MIF",14,"PRO A   1;MET A   2;LYS A  32;ASN A  35;ARG A  36;ILE A  37;ALA A  38;HIS C  49;SER A  63;ILE A  64;ILE C  95;VAL A 106;PHE A 108;VAL A 113","FUN A 201\r"],["6DE9_A_FUNA202","6de9","FUN","Furosemide (DB00695)","Homo sapiens","CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1","zf-CDGSH",6,"LYS A  68;VAL A  70;CYS A  83;HIS A  87;PRO A 100;ILE A 102","FUN A 202\r"],["6SG0_A_FUNA306","6sg0","FUN","Furosemide (DB00695)","Homo sapiens","CARBONIC ANHYDRASE 2","Carb_anhydrase",21,"ASN A  62;HIS A  64;ASN A  67;GLN A  92;HIS A  94;HIS A  96;GLU A 106;HIS A 119;VAL A 121;PHE A 131;VAL A 135;LEU A 141;VAL A 143;SER A 197;LEU A 198;THR A 199;THR A 200;PRO A 202;LEU A 204;VAL A 207;TRP A 209","FUN A 306\r"]]