Results: Ligand

Ligand ID: AZM

Drugbank ID:
Acetazolamide
(DB00819)

Indication:
Acetazolamide is a carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma.

LIST OF BINDING INTERFACES for query 'DB00819'
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
1AZM_A_AZMA262	1azm	AZM	Acetazolamide (DB00819)	Homo sapiens	CARBONIC ANHYDRASE I	Carb_anhydrase	13	PHE A 91 HIS A 94 HIS A 96 GLU A 106 HIS A 119 LEU A 131 LEU A 141 VAL A 143 SER A 197 LEU A 198 THR A 199 HIS A 200 TRP A 209	AZM A 262
1DMY_A_AZMA400	1dmy	AZM	Acetazolamide (DB00819)	Mus musculus	MURINE CARBONIC ANHYDRASE V	NA	16	PHE A 65 GLN A 92 HIS A 94 HIS A 96 GLU A 106 HIS A 119 VAL A 121 TYR A 131 SER A 135 LEU A 141 VAL A 143 SER A 197 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM A 400
1JD0_A_AZMA1400	1jd0	AZM	Acetazolamide (DB00819)	Homo sapiens	CARBONIC ANHYDRASE XII	Carb_anhydrase	12	GLN A 92 HIS A 94 HIS A 96 GLU A 106 HIS A 119 VAL A 121 VAL A 143 SER A 197 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM A1400
1RJ6_A_AZMA400	1rj6	AZM	Acetazolamide (DB00819)	Mus musculus	CARBONIC ANHYDRASE XIV	Carb_anhydrase	12	GLN A 92 HIS A 94 HIS A 96 HIS A 119 VAL A 121 LEU A 131 VAL A 143 SER A 197 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM A 400
2UY4_A_AZMA1311	2uy4	AZM	Acetazolamide (DB00819)	Saccharomyces cerevisiae	ENDOCHITINASE	NA	11	TYR A 32 PHE A 60 GLY A 109 ALA A 110 ASP A 155 GLU A 157 ALA A 187 GLN A 212 TYR A 214 ALA A 254 TRP A 285	AZM A1311
2XTK_A_AZMA1339	2xtk	AZM	Acetazolamide (DB00819)	Aspergillus fumigatus	CLASS III CHITINASE CHIA1	Glyco_hydro_18	16	TYR A 34 PHE A 60 GLY A 123 ALA A 124 ASP A 172 GLU A 174 ASN B 193 GLN B 194 ALA A 205 GLN A 230 TYR A 232 ASN A 233 ALA A 279 ALA A 280 MET A 310 TRP A 312	AZM A1339
3CZV_A_AZMA263	3czv	AZM	Acetazolamide (DB00819)	Homo sapiens	CARBONIC ANHYDRASE 13	Carb_anhydrase	15	GLN A 92 HIS A 94 HIS A 96 GLU A 106 HIS A 119 VAL A 121 SER B 130 PHE A 131 VAL B 132 VAL A 143 SER A 197 LEU A 198 THR A 199 VAL A 200 TRP A 209	AZM A 263
3HS4_A_AZMA701	3hs4	AZM	Acetazolamide (DB00819)	Homo sapiens	CARBONIC ANHYDRASE 2	Carb_anhydrase	13	GLN A 92 HIS A 94 HIS A 96 GLU A 106 HIS A 119 VAL A 121 PHE A 131 VAL A 143 SER A 197 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM A 701
3HS4_A_AZMA702	3hs4	AZM	Acetazolamide (DB00819)	Homo sapiens	CARBONIC ANHYDRASE 2	Carb_anhydrase	7	VAL A 109 LYS A 112 TYR A 114 TRP A 192 LYS A 213 GLU A 214 PRO A 215	AZM A 702
3HS4_A_AZMA703	3hs4	AZM	Acetazolamide (DB00819)	Homo sapiens	CARBONIC ANHYDRASE 2	Carb_anhydrase	10	HIS A 4 TRP A 5 HIS A 10 ASN A 11 GLY A 12 HIS A 15 TRP A 16 LYS A 18 ASP A 19 PHE A 20	AZM A 703
3IAI_A_AZMA263	3iai	AZM	Acetazolamide (DB00819)	Homo sapiens	CARBONIC ANHYDRASE 9	NA	12	GLN A 92 HIS A 94 HIS A 96 GLU A 106 HIS A 119 VAL A 121 VAL A 131 VAL A 143 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM A 263
3ML5_A_AZMA264	3ml5	AZM	Acetazolamide (DB00819)	Homo sapiens	CARBONIC ANHYDRASE 7	Carb_anhydrase	13	GLN A 92 HIS A 94 HIS A 96 GLU A 106 HIS A 119 VAL A 121 PHE A 131 VAL A 143 SER A 197 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM A 264
3UCJ_A_AZMA229	3ucj	AZM	Acetazolamide (DB00819)	Coccomyxa sp. pa	CARBONIC ANHYDRASE	Pro_CA	15	GLN B 38 CYS A 47 ASP A 49 PHE B 66 VAL A 71 GLY A 72 TYR B 88 HIS A 103 CYS A 106 GLY A 107 ALA A 108 ALA A 111 TRP A 115 THR A 123 ILE A 127	AZM A 229
4G7A_A_AZMA302	4g7a	AZM	Acetazolamide (DB00819)	Sulfurihydrogenibium sp. yo3aop1	CARBONATE DEHYDRATASE	Carb_anhydrase	12	GLN A 87 HIS A 89 HIS A 91 GLU A 95 HIS A 108 VAL A 110 VAL A 120 SER A 172 LEU A 173 THR A 174 THR A 175 TRP A 184	AZM A 302
4LU3_A_AZMA302	4lu3	AZM	Acetazolamide (DB00819)	Homo sapiens	CARBONIC ANHYDRASE 14	Carb_anhydrase	15	GLN A 92 HIS A 94 HIS A 96 GLU A 106 HIS A 119 VAL A 121 LEU A 131 ALA A 135 LEU A 141 VAL A 143 SER A 197 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM A 302
4UOV_A_AZMA299	4uov	AZM	Acetazolamide (DB00819)	Thermovibrio ammonificans	CARBONATE DEHYDRATASE	Carb_anhydrase	12	GLN A 110 HIS A 112 HIS A 114 GLU A 118 HIS A 131 VAL A 133 VAL A 143 SER A 196 LEU A 197 THR A 198 THR A 199 TRP A 208	AZM A 299
4X5S_A_AZMA302	4x5s	AZM	Acetazolamide (DB00819)	Sulfurihydrogenibium azorense	CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE)	Carb_anhydrase	12	GLN A 87 HIS A 89 HIS A 91 GLU A 95 HIS A 108 VAL A 110 VAL A 120 SER A 172 LEU A 173 THR A 174 THR A 175 TRP A 184	AZM A 302
4XIW_A_AZMA402	4xiw	AZM	Acetazolamide (DB00819)	Chlamydomonas reinhardtii	CARBONIC ANHYDRASE, ALPHA TYPE	Carb_anhydrase	14	GLN A 158 HIS A 160 HIS A 162 GLU A 166 HIS A 179 VAL A 181 LEU A 190 VAL A 192 VAL H 218 SER A 252 LEU A 253 THR A 254 THR A 255 TRP A 264	AZM A 402
4YGF_A_AZMA303	4ygf	AZM	Acetazolamide (DB00819)	Helicobacter pylori	ALPHA-CARBONIC ANHYDRASE	Carb_anhydrase	13	LYS A 88 ASN A 108 HIS A 110 HIS A 112 GLU A 116 HIS A 129 VAL A 131 VAL A 141 SER A 189 LEU A 190 THR A 191 ALA A 192 TRP A 201	AZM A 303
5JN8_A_AZMA701	5jn8	AZM	Acetazolamide (DB00819)	Homo sapiens	CARBONIC ANHYDRASE 4	NA	12	GLN A 92 HIS A 94 HIS A 96 GLU A 106 HIS A 119 VAL A 121 VAL A 143 SER A 197 LEU A 198 THR A 199 THR A 200 TRP A 209	AZM A 701
5NEK_B_AZMB302	5nek	AZM	Acetazolamide (DB00819)	Bacillus cereus	PEPTIDOGLYCAN N-ACETYLGLUCOSAMINE DEACETYLASE	Polysacc_deac_1	13	ASP B 76 ASP B 77 HIS B 126 HIS B 130 PRO B 165 PRO B 166 TYR B 167 GLY B 168 TRP B 191 TRP B 198 ARG B 199 LEU B 228 HIS B 230	AZM B 302
6IM3_A_AZMA302	6im3	AZM	Acetazolamide (DB00819)	Persephonella marina (strain dsm 14350 / ex-h1)	CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE)	Carb_anhydrase	12	GLN A 105 HIS A 107 HIS A 109 GLU A 113 HIS A 126 VAL A 128 VAL A 138 SER A 191 LEU A 192 THR A 193 THR A 194 TRP A 203	AZM A 302
6MWJ_A_AZMA201	6mwj	AZM	Acetazolamide (DB00819)	Burkholderia pseudomallei (strain 1710b)	2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE	YgbB	12	ASP A 10 HIS A 12 SER A 37 HIS A 44 ILE A 59 GLY A 60 PHE A 63 SER A 64 ASP A 65 PHE A 70 LEU A 78 LYS B 134	AZM A 201
7COJ_A_AZMA302	7coj	AZM	Acetazolamide (DB00819)	Neosartorya fumigata (strain atcc mya-4609 / af293 / cbs 101355 / fgsc a1100)	CARBONIC ANHYDRASE	Pro_CA	16	GLN B 110 CYS A 119 ASP A 121 PHE B 138 ILE A 143 ALA A 144 PHE B 160 HIS B 164 HIS A 175 CYS A 178 GLY A 179 GLY A 180 ALA A 183 LEU A 190 LEU A 193 LEU A 197	AZM A 302
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["1AZM_A_AZMA262","1azm","AZM","Acetazolamide (DB00819)","Homo sapiens","CARBONIC ANHYDRASE I","Carb_anhydrase",13,"PHE A  91;HIS A  94;HIS A  96;GLU A 106;HIS A 119;LEU A 131;LEU A 141;VAL A 143;SER A 197;LEU A 198;THR A 199;HIS A 200;TRP A 209","AZM A 262\r"],["1DMY_A_AZMA400","1dmy","AZM","Acetazolamide (DB00819)","Mus musculus","MURINE CARBONIC ANHYDRASE V","NA",16,"PHE A  65;GLN A  92;HIS A  94;HIS A  96;GLU A 106;HIS A 119;VAL A 121;TYR A 131;SER A 135;LEU A 141;VAL A 143;SER A 197;LEU A 198;THR A 199;THR A 200;TRP A 209","AZM A 400\r"],["1JD0_A_AZMA1400","1jd0","AZM","Acetazolamide (DB00819)","Homo sapiens","CARBONIC ANHYDRASE XII","Carb_anhydrase",12,"GLN A  92;HIS A  94;HIS A  96;GLU A 106;HIS A 119;VAL A 121;VAL A 143;SER A 197;LEU A 198;THR A 199;THR A 200;TRP A 209","AZM A1400\r"],["1RJ6_A_AZMA400","1rj6","AZM","Acetazolamide (DB00819)","Mus musculus","CARBONIC ANHYDRASE XIV","Carb_anhydrase",12,"GLN A  92;HIS A  94;HIS A  96;HIS A 119;VAL A 121;LEU A 131;VAL A 143;SER A 197;LEU A 198;THR A 199;THR A 200;TRP A 209","AZM A 400\r"],["2UY4_A_AZMA1311","2uy4","AZM","Acetazolamide (DB00819)","Saccharomyces cerevisiae","ENDOCHITINASE","NA",11,"TYR A  32;PHE A  60;GLY A 109;ALA A 110;ASP A 155;GLU A 157;ALA A 187;GLN A 212;TYR A 214;ALA A 254;TRP A 285","AZM A1311\r"],["2XTK_A_AZMA1339","2xtk","AZM","Acetazolamide (DB00819)","Aspergillus fumigatus","CLASS III CHITINASE CHIA1","Glyco_hydro_18",16,"TYR A  34;PHE A  60;GLY A 123;ALA A 124;ASP A 172;GLU A 174;ASN B 193;GLN B 194;ALA A 205;GLN A 230;TYR A 232;ASN A 233;ALA A 279;ALA A 280;MET A 310;TRP A 312","AZM A1339\r"],["3CZV_A_AZMA263","3czv","AZM","Acetazolamide (DB00819)","Homo sapiens","CARBONIC ANHYDRASE 13","Carb_anhydrase",15,"GLN A  92;HIS A  94;HIS A  96;GLU A 106;HIS A 119;VAL A 121;SER B 130;PHE A 131;VAL B 132;VAL A 143;SER A 197;LEU A 198;THR A 199;VAL A 200;TRP A 209","AZM A 263\r"],["3HS4_A_AZMA701","3hs4","AZM","Acetazolamide (DB00819)","Homo sapiens","CARBONIC ANHYDRASE 2","Carb_anhydrase",13,"GLN A  92;HIS A  94;HIS A  96;GLU A 106;HIS A 119;VAL A 121;PHE A 131;VAL A 143;SER A 197;LEU A 198;THR A 199;THR A 200;TRP A 209","AZM A 701\r"],["3HS4_A_AZMA702","3hs4","AZM","Acetazolamide (DB00819)","Homo sapiens","CARBONIC ANHYDRASE 2","Carb_anhydrase",7,"VAL A 109;LYS A 112;TYR A 114;TRP A 192;LYS A 213;GLU A 214;PRO A 215","AZM A 702\r"],["3HS4_A_AZMA703","3hs4","AZM","Acetazolamide (DB00819)","Homo sapiens","CARBONIC ANHYDRASE 2","Carb_anhydrase",10,"HIS A   4;TRP A   5;HIS A  10;ASN A  11;GLY A  12;HIS A  15;TRP A  16;LYS A  18;ASP A  19;PHE A  20","AZM A 703\r"],["3IAI_A_AZMA263","3iai","AZM","Acetazolamide (DB00819)","Homo sapiens","CARBONIC ANHYDRASE 9","NA",12,"GLN A  92;HIS A  94;HIS A  96;GLU A 106;HIS A 119;VAL A 121;VAL A 131;VAL A 143;LEU A 198;THR A 199;THR A 200;TRP A 209","AZM A 263\r"],["3ML5_A_AZMA264","3ml5","AZM","Acetazolamide (DB00819)","Homo sapiens","CARBONIC ANHYDRASE 7","Carb_anhydrase",13,"GLN A  92;HIS A  94;HIS A  96;GLU A 106;HIS A 119;VAL A 121;PHE A 131;VAL A 143;SER A 197;LEU A 198;THR A 199;THR A 200;TRP A 209","AZM A 264\r"],["3UCJ_A_AZMA229","3ucj","AZM","Acetazolamide (DB00819)","Coccomyxa sp. pa","CARBONIC ANHYDRASE","Pro_CA",15,"GLN B  38;CYS A  47;ASP A  49;PHE B  66;VAL A  71;GLY A  72;TYR B  88;HIS A 103;CYS A 106;GLY A 107;ALA A 108;ALA A 111;TRP A 115;THR A 123;ILE A 127","AZM A 229\r"],["4G7A_A_AZMA302","4g7a","AZM","Acetazolamide (DB00819)","Sulfurihydrogenibium sp. yo3aop1","CARBONATE DEHYDRATASE","Carb_anhydrase",12,"GLN A  87;HIS A  89;HIS A  91;GLU A  95;HIS A 108;VAL A 110;VAL A 120;SER A 172;LEU A 173;THR A 174;THR A 175;TRP A 184","AZM A 302\r"],["4LU3_A_AZMA302","4lu3","AZM","Acetazolamide (DB00819)","Homo sapiens","CARBONIC ANHYDRASE 14","Carb_anhydrase",15,"GLN A  92;HIS A  94;HIS A  96;GLU A 106;HIS A 119;VAL A 121;LEU A 131;ALA A 135;LEU A 141;VAL A 143;SER A 197;LEU A 198;THR A 199;THR A 200;TRP A 209","AZM A 302\r"],["4UOV_A_AZMA299","4uov","AZM","Acetazolamide (DB00819)","Thermovibrio ammonificans","CARBONATE DEHYDRATASE","Carb_anhydrase",12,"GLN A 110;HIS A 112;HIS A 114;GLU A 118;HIS A 131;VAL A 133;VAL A 143;SER A 196;LEU A 197;THR A 198;THR A 199;TRP A 208","AZM A 299\r"],["4X5S_A_AZMA302","4x5s","AZM","Acetazolamide (DB00819)","Sulfurihydrogenibium azorense","CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE)","Carb_anhydrase",12,"GLN A  87;HIS A  89;HIS A  91;GLU A  95;HIS A 108;VAL A 110;VAL A 120;SER A 172;LEU A 173;THR A 174;THR A 175;TRP A 184","AZM A 302\r"],["4XIW_A_AZMA402","4xiw","AZM","Acetazolamide (DB00819)","Chlamydomonas reinhardtii","CARBONIC ANHYDRASE, ALPHA TYPE","Carb_anhydrase",14,"GLN A 158;HIS A 160;HIS A 162;GLU A 166;HIS A 179;VAL A 181;LEU A 190;VAL A 192;VAL H 218;SER A 252;LEU A 253;THR A 254;THR A 255;TRP A 264","AZM A 402\r"],["4YGF_A_AZMA303","4ygf","AZM","Acetazolamide (DB00819)","Helicobacter pylori","ALPHA-CARBONIC ANHYDRASE","Carb_anhydrase",13,"LYS A  88;ASN A 108;HIS A 110;HIS A 112;GLU A 116;HIS A 129;VAL A 131;VAL A 141;SER A 189;LEU A 190;THR A 191;ALA A 192;TRP A 201","AZM A 303\r"],["5JN8_A_AZMA701","5jn8","AZM","Acetazolamide (DB00819)","Homo sapiens","CARBONIC ANHYDRASE 4","NA",12,"GLN A  92;HIS A  94;HIS A  96;GLU A 106;HIS A 119;VAL A 121;VAL A 143;SER A 197;LEU A 198;THR A 199;THR A 200;TRP A 209","AZM A 701\r"],["5NEK_B_AZMB302","5nek","AZM","Acetazolamide (DB00819)","Bacillus cereus","PEPTIDOGLYCAN N-ACETYLGLUCOSAMINE DEACETYLASE","Polysacc_deac_1",13,"ASP B  76;ASP B  77;HIS B 126;HIS B 130;PRO B 165;PRO B 166;TYR B 167;GLY B 168;TRP B 191;TRP B 198;ARG B 199;LEU B 228;HIS B 230","AZM B 302\r"],["6IM3_A_AZMA302","6im3","AZM","Acetazolamide (DB00819)","Persephonella marina (strain dsm 14350 \/ ex-h1)","CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE)","Carb_anhydrase",12,"GLN A 105;HIS A 107;HIS A 109;GLU A 113;HIS A 126;VAL A 128;VAL A 138;SER A 191;LEU A 192;THR A 193;THR A 194;TRP A 203","AZM A 302\r"],["6MWJ_A_AZMA201","6mwj","AZM","Acetazolamide (DB00819)","Burkholderia pseudomallei (strain 1710b)","2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE","YgbB",12,"ASP A  10;HIS A  12;SER A  37;HIS A  44;ILE A  59;GLY A  60;PHE A  63;SER A  64;ASP A  65;PHE A  70;LEU A  78;LYS B 134","AZM A 201\r"],["7COJ_A_AZMA302","7coj","AZM","Acetazolamide (DB00819)","Neosartorya fumigata (strain atcc mya-4609 \/ af293 \/ cbs 101355 \/ fgsc a1100)","CARBONIC ANHYDRASE","Pro_CA",16,"GLN B 110;CYS A 119;ASP A 121;PHE B 138;ILE A 143;ALA A 144;PHE B 160;HIS B 164;HIS A 175;CYS A 178;GLY A 179;GLY A 180;ALA A 183;LEU A 190;LEU A 193;LEU A 197","AZM A 302\r"]]