Ligand ID: BZ1

Drugbank ID:
Brinzolamide
(DB01194)

Indication:
Brinzolamide is a carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.

LIST OF BINDING INTERFACES for query 'BZ1'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3ZNC_A_BZ1A500	3znc	BZ1	Brinzolamide (DB01194)	Mus musculus	CARBONIC ANHYDRASE IV	Carb_anhydrase	18	TRP A   5 ASN A  62 THR A  65 GLN A  92 HIS A  94 HIS A  96 GLU A 106 HIS A 119 VAL A 121 LYS A 123 PHE A 141 VAL A 143 SER A 197 LEU A 198 THR A 199 THR A 200 PRO A 201 TRP A 209	BZ1 A 500		Details
4M2V_A_BZ1A302	4m2v	BZ1	Brinzolamide (DB01194)	Homo sapiens	CARBONIC ANHYDRASE 2	Carb_anhydrase	23	TRP A   5 ASN A  62 HIS A  64 LEU A  91 GLN A  92 HIS A  94 HIS A  96 GLU A 106 HIS A 119 VAL A 121 VAL A 131 GLY A 132 VAL A 135 LEU A 141 VAL A 143 SER A 197 LEU A 198 THR A 199 THR A 200 PRO A 201 PRO A 202 VAL A 207 TRP A 209	BZ1 A 302		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3ZNC_A_BZ1A500","3znc","BZ1","Brinzolamide (DB01194)","Mus musculus","CARBONIC ANHYDRASE IV","Carb_anhydrase",18,"TRP A 5;ASN A 62;THR A 65;GLN A 92;HIS A 94;HIS A 96;GLU A 106;HIS A 119;VAL A 121;LYS A 123;PHE A 141;VAL A 143;SER A 197;LEU A 198;THR A 199;THR A 200;PRO A 201;TRP A 209","BZ1 A 500\r"],["4M2V_A_BZ1A302","4m2v","BZ1","Brinzolamide (DB01194)","Homo sapiens","CARBONIC ANHYDRASE 2","Carb_anhydrase",23,"TRP A 5;ASN A 62;HIS A 64;LEU A 91;GLN A 92;HIS A 94;HIS A 96;GLU A 106;HIS A 119;VAL A 121;VAL A 131;GLY A 132;VAL A 135;LEU A 141;VAL A 143;SER A 197;LEU A 198;THR A 199;THR A 200;PRO A 201;PRO A 202;VAL A 207;TRP A 209","BZ1 A 302\r"]]