
(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
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PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |
---|---|---|---|---|---|---|---|
1osv | CHC | Obeticholic acid (DB05990) | Obeticholic acid is a bile acid analog and farnesoid X receptor agonist used to treat primary biliary cholangitis in adult patients with inadequate clinical response or intolerance to UDCA. | BILE ACID RECEPTOR (Rattus norvegicus;synthetic construct) | Hormone_recep | ||
1ot7 | IU5 | Ursodeoxycholic acid (DB01586) | Ursodeoxycholic acid is a bile acid used for the treatment of primary biliary cirrhosis (PBC), dissolution of radiolucent gallstones in patients with a functioning gallbladder, and treatment of hepatobiliary disorders associated with cystic fibrosis in pediatric patients. | BILE ACID RECEPTOR (Rattus norvegicus;synthetic construct) | Hormone_recep | ||
4wvd | IVM | Ivermectin (DB00602) | Ivermectin is an anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis. | BILE ACID RECEPTOR (Homo sapiens;synthetic construct) | NA | ||
6hl1 | JN3 | Chenodeoxycholic acid (DB06777) | Chenodeoxycholic acid is a bile acid used for the treatment of primary biliary cirrhosis. | BILE ACID RECEPTOR (Homo sapiens;synthetic construct) | Hormone_recep | ||
PDB | Ligand | Drug | Indication | Macromolecule/ Organism |
Pfam | Binding_Interfaces (View) | Details |