Ligand ID: IU5

Drugbank ID:
Ursodeoxycholic acid
(DB01586)

Indication:
Ursodeoxycholic acid is a bile acid used for the treatment of primary biliary cirrhosis (PBC), dissolution of radiolucent gallstones in patients with a functioning gallbladder, and treatment of hepatobiliary disorders associated with cystic fibrosis in pediatric patients.


LIST OF BINDING INTERFACES for query 'IU5'

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DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details
1IHI_A_IU5A3261ihi IU5Ursodeoxycholic acid
(DB01586) 		Homo sapiens 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE Aldo_ket_red 10TYR A  24
VAL A  54
TYR A  55
TRP A  86
HIS A 117
VAL A 128
ILE A 129
GLU A 224
TRP A 227
LEU A 308
IU5 A 326
1OT7_B_IU5B10021ot7 IU5Ursodeoxycholic acid
(DB01586) 		Rattus norvegicus;
synthetic construct 		BILE ACID RECEPTOR Hormone_recep 18MET B 262
LEU B 284
MET B 287
ALA B 288
HIS B 291
MET B 325
PHE B 326
ARG B 328
SER B 329
ILE B 332
PHE B 333
LEU B 345
ILE B 349
TYR B 358
TYR B 366
HIS B 444
TRP B 451
TRP B 466
IU5 B1002
DrReposER ID PDB Ligand Drug Organism Macromolecule Pfam Res. Interface HETATM View Details