Ligand ID: IVM

Drugbank ID:
Ivermectin
(DB00602)

Indication:
Ivermectin is an anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis.

LIST OF BINDING INTERFACES for query 'IVM'

(Click on the 'Details' column to view details on interfaces and similar patterns of amino acids)
(Click on the 'View' column to view patterns on the structural viewer)

DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details
3RHW_A_IVMA348	3rhw	IVM	Ivermectin (DB00602)	Caenorhabditis elegans; mus musculus	AVERMECTIN-SENSITIVE GLUTAMATE-GATED CHLORIDE CHANNEL GLUCL ALPHA	NA	19	LEU A 217 LEU A 218 GLN A 219 ILE A 222 PRO A 223 CYS A 225 MET A 226 ILE A 229 THR E 257 SER E 260 ASN E 264 ILE E 273 ASP E 277 ILE E 280 GLY E 281 ALA E 282 MET E 284 THR E 285 PHE E 288	IVM A 348		Details
4WVD_A_IVMA505	4wvd	IVM	Ivermectin (DB00602)	Homo sapiens; synthetic construct	BILE ACID RECEPTOR	NA	23	ARG A 264 LYS A 272 ILE A 273 GLU A 276 SER A 279 ASN A 283 LEU A 287 MET A 290 ALA A 291 ASN A 293 HIS A 294 VAL A 297 MET A 328 PHE A 329 ARG A 331 SER A 332 ILE A 335 ASP A 346 LEU A 348 ILE A 357 TYR A 361 ILE A 362 MET A 365	IVM A 505		Details
5VDH_A_IVMA403	5vdh	IVM	Ivermectin (DB00602)	Homo sapiens	GLYCINE RECEPTOR SUBUNIT ALPHA-3	Neur_chan_LBD	19	GLY B 221 LEU B 224 ILE B 225 GLN B 226 ILE B 229 PRO B 230 LEU B 232 LEU B 233 ILE B 236 THR A 264 SER A 267 SER A 268 SER A 278 VAL A 280 ASP A 284 ALA A 288 LEU A 291 LEU A 292 PHE A 295	IVM A 403		Details
6VM3_A_IVMA604	6vm3	IVM	Ivermectin (DB00602)	Danio rerio	GLYCINE RECEPTOR SUBUNIT ALPHAZ1	Neur_chan_LBD Neur_chan_memb	19	LEU B 248 ILE B 249 GLN B 250 ILE B 253 PRO B 254 LEU B 256 LEU B 257 ILE B 260 THR A 288 SER A 291 SER A 292 ARG A 295 SER A 302 VAL A 304 ASP A 308 ILE A 309 ALA A 312 LEU A 315 LEU A 316	IVM A 604		Details
DrReposER ID	PDB	Ligand	Drug	Organism	Macromolecule	Pfam	Res.	Interface	HETATM	View	Details

[["3RHW_A_IVMA348","3rhw","IVM","Ivermectin (DB00602)","Caenorhabditis elegans;mus musculus","AVERMECTIN-SENSITIVE GLUTAMATE-GATED CHLORIDE CHANNEL GLUCL ALPHA","NA",19,"LEU A 217;LEU A 218;GLN A 219;ILE A 222;PRO A 223;CYS A 225;MET A 226;ILE A 229;THR E 257;SER E 260;ASN E 264;ILE E 273;ASP E 277;ILE E 280;GLY E 281;ALA E 282;MET E 284;THR E 285;PHE E 288","IVM A 348\r"],["4WVD_A_IVMA505","4wvd","IVM","Ivermectin (DB00602)","Homo sapiens;synthetic construct","BILE ACID RECEPTOR","NA",23,"ARG A 264;LYS A 272;ILE A 273;GLU A 276;SER A 279;ASN A 283;LEU A 287;MET A 290;ALA A 291;ASN A 293;HIS A 294;VAL A 297;MET A 328;PHE A 329;ARG A 331;SER A 332;ILE A 335;ASP A 346;LEU A 348;ILE A 357;TYR A 361;ILE A 362;MET A 365","IVM A 505\r"],["5VDH_A_IVMA403","5vdh","IVM","Ivermectin (DB00602)","Homo sapiens","GLYCINE RECEPTOR SUBUNIT ALPHA-3","Neur_chan_LBD",19,"GLY B 221;LEU B 224;ILE B 225;GLN B 226;ILE B 229;PRO B 230;LEU B 232;LEU B 233;ILE B 236;THR A 264;SER A 267;SER A 268;SER A 278;VAL A 280;ASP A 284;ALA A 288;LEU A 291;LEU A 292;PHE A 295","IVM A 403\r"],["6VM3_A_IVMA604","6vm3","IVM","Ivermectin (DB00602)","Danio rerio","GLYCINE RECEPTOR SUBUNIT ALPHAZ1","Neur_chan_LBD;Neur_chan_memb",19,"LEU B 248;ILE B 249;GLN B 250;ILE B 253;PRO B 254;LEU B 256;LEU B 257;ILE B 260;THR A 288;SER A 291;SER A 292;ARG A 295;SER A 302;VAL A 304;ASP A 308;ILE A 309;ALA A 312;LEU A 315;LEU A 316","IVM A 604\r"]]